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Health Canada NPN 80109100 200mg Elemental Calcium · Dual Chelate Vegan · Non-GMO · Gluten-Free Made in Canada · 120-Day Supply
Calcium Malate Bis-GlycinateCalcium Malate Bis-Glycinate - benefits and key ingredients Calcium Malate Bis-Glycinate - lifestyleCalcium Malate Bis-Glycinate - ingredientsCalcium Malate Bis-Glycinate - supplement facts panel

CanPrev Calcium Malate Bis-Glycinate - Dual Chelate | 120 Caps

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$19.23 CAD ($0.16 / capsule)
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BrandCanPrev
Serving1 capsule (200 mg elemental calcium)
Licensed Natural Health ProductNPN 80109100
Quality StandardsMade in Canada
CountryMade in Canada Made in Canada

About this item

  • THERAPEUTIC 200MG ELEMENTAL CALCIUM: Each vegetable capsule delivers a full 200 mg of elemental calcium - a therapeutic dose in a single easy-to-swallow capsule.
  • DUAL ALBION CHELATES: Calcium is supplied as DimaCal Di-Calcium Malate and TRAACS Calcium Bisglycinate Chelate - two well-studied chelated forms combined in one formula, uniquely chelated and designed to be easy to absorb.
  • GENTLE ON DIGESTION: Formulated to be gentle on the digestive system - a common concern with higher-dose calcium carbonate supplements.
  • HELPS DEVELOP & MAINTAIN BONES AND TEETH: Calcium helps in the development and maintenance of bones and teeth.
  • SIMPLE FLEXIBLE DOSING: Take 1 to 4 capsules per day with food, or as directed by a qualified health care practitioner.
  • CLEAN VEGAN FORMULA: Vegan vegetable capsules, free from gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours, preservatives and animal products.
  • PREMIUM CANADIAN QUALITY: Formulated and made in Canada by CanPrev, licensed under Health Canada NPN 80109100.

Product Description

Calcium Malate Bis-Glycinate 200 - Gentle, Chelated Calcium for Bones & Teeth

CanPrev Calcium Malate Bis-Glycinate

A uniquely chelated, superior form of calcium that is easy to absorb and gentle on the digestive system - 200 mg of elemental calcium in every vegetable capsule, delivered as a dual blend of DimaCal Di-Calcium Malate and TRAACS Calcium Bisglycinate Chelate. Simple, single-ingredient formula with no binders or flavours. Licensed Natural Health Product NPN 80109100.

Une forme de calcium uniquement chélatée, supérieure, facile à absorber et douce pour le système digestif - 200 mg de calcium élémentaire dans chaque capsule végétale, sous forme d'un mélange de malate dicalcique DimaCal et de chélate de bisglycinate de calcium TRAACS. Formule simple, à un seul ingrédient, sans liants ni aromatisants. Produit de santé naturel homologué. NPN 80109100.

Calcium Malate Bis-Glycinate lifestyle
CanPrev Calcium Malate Bis-Glycinate
200mg Elemental Calcium · Dual Chelate · Vegan

One Capsule, Two Gentle Calcium Chelates

200mg Elemental Calcium as Di-Calcium Malate + Calcium Bisglycinate Chelate - Vegan, Non-GMO, Gluten-Free

Dual-Chelate Elemental Calcium

DimaCal Di-Calcium Malate and TRAACS Calcium Bisglycinate Chelate are combined to deliver 200 mg of elemental calcium per capsule - two Albion-chelated forms in one formula.

Formulated to Be Gentle on Digestion

Chelated calcium forms are designed to be easier on the stomach than plain calcium carbonate, without sacrificing the elemental calcium dose per capsule.

What Calcium Malate Bis-Glycinate 200 Supports

Calcium is essential for skeletal, muscular and cellular health - here is what CanPrev Calcium Malate Bis-Glycinate 200 is formulated to support.

Bone & Teeth Development

Helps in the development and maintenance of bones and teeth.

Chelated Absorption

Supplied as two chelated calcium forms (malate and bisglycinate chelate) studied for gentle, efficient uptake compared with plain calcium salts.

Muscle Function

Calcium is a mineral involved in normal muscle contraction and everyday physical function.

Daily Mobility

A simple, single-ingredient way to help maintain the calcium intake that supports an active daily life.

CanPrev Calcium Malate Bis-Glycinate: Supplement Facts

CanPrev™Calcium Malate Bis-Glycinate
English

Supplement Facts

  • Calcium (DimaCal Di-Calcium Malate, TRAACS Calcium Bisglycinate Chelate) per capsule200 mg

Non-Medicinal Ingredients: Non-medicinal ingredients: Vegetable-grade magnesium stearate, microcrystalline cellulose, maltodextrin, silica, vegetable capsule.

Recommended Use or Purpose: Helps in the development and maintenance of bones and teeth.

Recommended Dose (Adults): Take one (1) to four (4) capsules per day, or as directed by a qualified health care practitioner. Take a few hours before or after taking other medications.

Cautions and Warnings: As with any natural health product, you should consult a health care practitioner on the use of this product. Do not use if the safety seal is broken. Take a few hours before or after taking other medications, as calcium can reduce the absorption of some other medications and natural health products. Keep out of reach of children.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

Français

Fiche produit

  • Calcium (malate dicalcique DimaCal, chélate de bisglycinate de calcium TRAACS) par capsule200 mg

Ingrédients non médicinaux : Ingrédients non médicinaux : Stéarate de magnésium de grade végétal, cellulose microcristalline, maltodextrine, silice, capsule végétale.

Usage ou fins recommandés : Aide au développement et au maintien des os et des dents.

Posologie recommandée (adultes) : Prendre une (1) à quatre (4) capsules par jour, ou selon l'avis d'un praticien de soins de santé qualifié. Prendre quelques heures avant ou après la prise d'autres médicaments.

Mises en garde : Comme pour tout produit de santé naturel, vous devriez consulter un praticien de soins de santé concernant l'utilisation de ce produit. Ne pas utiliser si le sceau de sécurité est brisé. Prendre quelques heures avant ou après la prise d'autres médicaments, car le calcium peut réduire l'absorption de certains autres médicaments et produits de santé naturels. Garder hors de la portée des enfants.

NPN 80109100

200mg Elemental Calcium · Dual-ChelateMalate + Bisglycinate · Vegan120 Capsules · 120-Day SupplyMade in Canada

Support strong bones, teeth and daily mobility

Get CanPrev Calcium Malate Bis-Glycinate 200 on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why CanPrev Calcium Malate Bis-Glycinate 200

A therapeutic 200mg dose of dual-chelated elemental calcium, formulated to be gentle and well absorbed - premium CanPrev quality.

Therapeutic 200mg elemental calcium

A clinically relevant 200 mg dose of elemental calcium in every vegetable capsule.

Dual chelated forms

DimaCal Di-Calcium Malate and TRAACS Calcium Bisglycinate Chelate combined in one gentle, absorbable formula.

Helps develop & maintain bones and teeth

Calcium helps in the development and maintenance of bones and teeth.

Premium Canadian brand

CanPrev - Pro Essentials line, formulated and made in Canada. NPN 80109100.

How to use it

Take 1 to 4 capsules daily

Adults take one (1) to four (4) capsules per day, or as directed by a qualified health care practitioner.

With food

Take with a meal for comfort, or as directed by a health care practitioner.

Space out other medications

Take a few hours before or after taking other medications or natural health products, since calcium can interfere with the absorption of some of them.

Consult a practitioner if unsure

As with any natural health product, consult a health care practitioner on the use of this product.

What the research says about calcium

Educational summaries of published research on calcium and its chelated (malate, bisglycinate) forms; not product-specific claims. CanPrev Calcium Malate Bis-Glycinate 200's claim is the authorized use under NPN 80109100.

Bone Mineral Density & Postmenopausal Bone Health

Combined calcium/vitamin D plus exercise improved bone density

A meta-analysis of 13 RCTs in postmenopausal women found that exercise combined with calcium and vitamin D supplementation significantly increased lumbar spine and femoral neck bone mineral density compared with calcium and vitamin D alone.

Meta-analysis
Bai et al., Nutrients (2025)
Bone Mineral Density & Postmenopausal Bone Health

Modest pelvic bone density gains, no significant fracture reduction

A meta-analysis of 11 RCTs (43,869 participants) found combined calcium and vitamin D supplementation modestly improved pelvic bone mineral density and corrected vitamin D deficiency in postmenopausal women with osteoporosis, but did not significantly reduce overall fracture risk.

Meta-analysis
Cong & Zhang, BMC Musculoskeletal Disorders (2025)
Bone Mineral Density & Postmenopausal Bone Health

Calcium supplementation raised a bone-formation marker

A network meta-analysis of 43 RCTs in postmenopausal women found calcium supplementation produced the largest increase in alkaline phosphatase, a marker associated with bone formation, among the dietary supplements compared.

Network meta-analysis
Wei et al., PeerJ (2025)
Calcium Absorption & Chelated Forms

Carbonate and citrate forms absorb similarly when taken with food

A controlled human study found that when taken with a meal, calcium absorption from the carbonate salt was essentially equal to absorption from the citrate salt, with only a very small difference between sources.

Human RCT
Heaney et al., Osteoporosis International (1999)
Calcium Absorption & Chelated Forms

An amino-acid-chelated calcium form showed higher relative bioavailability

In a randomized trial comparing calcium lysinate, calcium carbonate and calcium citrate malate in osteopenia patients, calcium lysinate showed a relative oral bioavailability of 223% and the most significant improvement in bone mineral density T-scores over 8 weeks.

Human RCT
Shankar et al., Journal of Orthopaedic Case Reports (2018)
Calcium Absorption & Chelated Forms

Peptide chelation may enhance calcium transport into bone cells

A laboratory study found a glycated peptide-calcium chelate bound calcium via carboxyl and amino groups, resisted digestive breakdown, and promoted calcium transport through TRPV6 and CAV1.3 channels into osteoblast cells, supporting mineralization in that cell model.

Preclinical study
Wang et al., Food Chemistry (2025)
Muscle Function & Cramps

Calcium handling is central to how muscle cramps end

A 2026 narrative review proposes that muscle cramps persist when calcium handling, motor unit activity and the energy-dependent relaxation process are disrupted, framing cramps as a problem of impaired contraction termination rather than simple overactivation.

Review
Takahashi, Physiological Reports (2026)
Muscle Function & Cramps

Oral calcium showed mixed results for pregnancy-related leg cramps

A Cochrane review of interventions for leg cramps in pregnancy found the evidence on oral calcium versus no treatment was very uncertain, with one small trial suggesting a possible reduction in cramp frequency, but data too limited to draw firm conclusions.

Cochrane Review
Luo et al., Cochrane Database of Systematic Reviews (2020)
Muscle Function & Cramps

Magnesium (compared with calcium and other agents) reviewed for cramp prevention

A Cochrane review of magnesium for skeletal muscle cramps - which included trials comparing magnesium against calcium carbonate, vitamin B and vitamin E - found magnesium unlikely to meaningfully reduce cramp frequency in older adults with idiopathic cramps.

Cochrane Review
Garrison et al., Cochrane Database of Systematic Reviews (2020)
Calcium, Vitamin D & Fracture Prevention

Combined calcium and vitamin D reduced hip fractures in a landmark trial

A cost-effectiveness analysis based on the 3-year Decalyos trial in 3,270 institutionalized elderly women found that 1,200 mg/day calcium plus 800 IU/day vitamin D3 reduced hip fractures (138 vs 184 cases) compared with placebo, and was cost-saving overall.

Human RCT
Lilliu et al., Maturitas (2003)
Calcium, Vitamin D & Fracture Prevention

Vitamin D alone, without calcium, did not reduce fracture risk

A meta-analysis of 7 RCTs (71,899 healthy older adults) found vitamin D supplementation alone did not reduce total fracture incidence, and was associated with increased hip fracture risk in women - a finding the authors suggest may apply mainly when calcium intake is inadequate.

Meta-analysis
de Souza et al., Journal of General Internal Medicine (2024)
Calcium, Vitamin D & Fracture Prevention

Multivitamin/mineral supplementation alone did not lower fracture risk

In the large COSMOS trial ancillary study of 21,442 older adults, a daily multivitamin/multimineral supplement was not associated with a lower risk of total clinical fracture, hip fracture, or nonvertebral fracture compared with placebo.

Human RCT
Crandall et al., Journal of Bone and Mineral Research (2025)
Cardiovascular Safety Research

No significant cardiovascular hazard across 12 randomized trials

A meta-analysis of 12 RCTs found calcium supplementation was not associated with myocardial infarction, total stroke, heart failure admission, or all-cause/cardiovascular mortality.

Meta-analysis
Sim et al., Heart, Lung & Circulation (2023)
Cardiovascular Safety Research

Calcium alone or with vitamin D showed no excess cardiovascular risk

A meta-analysis of RCTs covering over 55,000 participants found calcium supplements, taken alone or with vitamin D, were not associated with any significant excess risk of heart attack, coronary heart disease death, stroke, or all-cause mortality.

Meta-analysis
Huo et al., Current Developments in Nutrition (2023)
Cardiovascular Safety Research

Calcium and magnesium supplementation modestly lowered blood pressure

A systematic review and meta-analysis of 24 studies found calcium and magnesium supplementation each produced a small but significant reduction in diastolic blood pressure in hypertensive patients, without a significant effect on systolic pressure.

Meta-analysis
Amer et al., BMC Complementary Medicine and Therapies (2025)
Calcium Requirements Across the Lifespan

Calcium intake has grade-A evidence for peak bone mass

A National Osteoporosis Foundation systematic review identified calcium intake and physical activity as having the strongest (grade A) evidence for promoting peak bone mass development, particularly during the peripubertal years.

Systematic Review
Weaver et al., Osteoporosis International (2016)
Calcium Requirements Across the Lifespan

Calcium remains a primary nutritional focus for osteoporosis prevention

A review of osteoporosis prevention and nutrition notes that while calcium and vitamin D supplementation trial results have been inconsistent, calcium intake remains a primary focus, alongside other nutrients such as magnesium, vitamin K and protein.

Review
Tucker, Current Osteoporosis Reports (2009)
Calcium Requirements Across the Lifespan

Adequate calcium intake supports the bone benefits of dietary protein

An expert consensus review found that higher dietary protein intake was associated with higher bone mineral density and reduced hip fracture risk in older adults, provided that calcium intakes were also adequate.

Consensus Review
Rizzoli et al., Osteoporosis International (2018)
Calcium in Cellular Signaling: Nerve, Heart & Clotting

Phosphate and calcium dynamics are tightly linked at the cellular level

A 2026 review describes how intracellular and extracellular phosphate influence calcium signaling, buffering and transport - including the pumps that move calcium in and out of cells - with hormones like vitamin D and parathyroid hormone coordinating the two minerals.

Review
Shahzad & Razzaque, Cells (2026)
Calcium in Cellular Signaling: Nerve, Heart & Clotting

Calcium cycling links energy supply to nerve and muscle excitability

A 2026 review proposes that capillary blood flow and mitochondria work together to supply the ATP needed for calcium cycling that underlies electrical activity in both heart muscle and neurons.

Review
Santana & Earley, The Journal of Physiology (2026)
Calcium in Cellular Signaling: Nerve, Heart & Clotting

Blood calcium levels linked to outcomes after a vascular emergency

A study of 267 patients with spontaneous subarachnoid hemorrhage found that lower ionized calcium levels on admission - calcium acting as a cofactor in cardiac contractility, vascular tone and the coagulation cascade - were associated with higher mortality and poorer neurological outcomes.

Cohort Study
Kucukceylan et al., World Neurosurgery (2024)
Bone Nutrition: Cohort & Mechanistic Evidence

Framingham cohort data highlights calcium among key bone nutrients

A review of the Framingham Osteoporosis Study's research on more than 5,000 adults reports that, alongside calcium and vitamin D, several other nutrients and dietary patterns are associated with bone mineral density and fracture outcomes.

Cohort Review
Sahni et al., Current Osteoporosis Reports (2015)
Bone Nutrition: Cohort & Mechanistic Evidence

Standard calcium and vitamin D therapy remains the background of osteoporosis trials

In a randomized trial testing whether adding vitamin K to standard bisphosphonate treatment improved bone outcomes, all participants continued their existing oral calcium and/or vitamin D therapy throughout - underscoring calcium's role as a nutritional foundation for osteoporosis management.

Human RCT
Moore et al., Archives of Osteoporosis (2023)
Bone Nutrition: Cohort & Mechanistic Evidence

A calcium-binding peptide increased bone mass in an animal model

A novel calcium-chelating peptide isolated from fermented soy yogurt was shown to bind calcium ions via its carboxyl and amino groups and, in a zebrafish osteoporosis model, substantially increased bone mass.

Animal study
Gan et al., Journal of the Science of Food and Agriculture (2022)

Frequently asked questions

What is CanPrev Calcium Malate Bis-Glycinate 200 and what does it do?

It's a 200 mg dose of elemental calcium per vegetable capsule, supplied as DimaCal Di-Calcium Malate and TRAACS Calcium Bisglycinate Chelate. Calcium helps in the development and maintenance of bones and teeth.

How do I take it?

Adults take 1 to 4 capsules per day, with food, or as directed by a qualified health care practitioner.

Does it contain magnesium or other minerals?

No - the medicinal ingredient is calcium only, supplied as two chelated forms (Di-Calcium Malate and Calcium Bisglycinate Chelate) totalling 200 mg elemental calcium per capsule. It does not contain added magnesium or other medicinal minerals.

Why chelated calcium instead of calcium carbonate?

Chelated forms such as calcium malate and calcium bisglycinate are formulated to be gentle on the digestive system and easy to absorb, which is why CanPrev uses this dual-chelate blend instead of plain calcium carbonate.

How long does one bottle last?

Each bottle contains 120 vegetable capsules - at 1 capsule daily that is a 120-day supply; taken more frequently as directed, the bottle will last a shorter time.

Is it vegan?

Yes - the vegetable capsule and all ingredients are vegan, with a clean formula free of GMOs, gluten, dairy, soy, wheat and yeast.

Who should use caution, or not use it?

As with any natural health product, consult a health care practitioner on the use of this product. Do not use if the safety seal is broken. Take a few hours before or after other medications or natural health products, since calcium can reduce their absorption.

Where do I buy it?

Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.

200mg Elemental Calcium · Dual-ChelateMalate + Bisglycinate · Vegan120 Capsules · 120-Day SupplyMade in Canada

Support strong bones, teeth and daily mobility

Get CanPrev Calcium Malate Bis-Glycinate 200 on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80109100. Calcium helps in the development and maintenance of bones and teeth. The research summaries below concern calcium generally and are educational - they are not claims about this finished product. Read and follow the label. As with any natural health product, consult a health care practitioner on the use of this product. Do not use if the safety seal is broken. Results may vary.

Important information

Safety Information

Cautions and Warnings: As with any natural health product, you should consult a health care practitioner on the use of this product. Do not use if the safety seal is broken. Take a few hours before or after taking other medications, as calcium can reduce the absorption of some other medications and natural health products. Keep out of reach of children.

Indications

Recommended Use or Purpose: Helps in the development and maintenance of bones and teeth.

Ingredients

Medicinal ingredients (per capsule): Calcium (DimaCal Di-Calcium Malate, TRAACS Calcium Bisglycinate Chelate) 200 mg. Non-medicinal ingredients: Vegetable-grade magnesium stearate, microcrystalline cellulose, maltodextrin, silica, vegetable capsule. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.

Directions

Recommended Dose (Adults): Take one (1) to four (4) capsules per day, or as directed by a qualified health care practitioner. Take a few hours before or after taking other medications.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.