CanPrev B9 Folate 200mcg + B12 20mcg - Liquid Drops | 15ml
Visit the CanPrev Store Read all reviews on Amazon →| Brand | CanPrev |
| Serving | 5 drops (adults 19+) |
| Licensed Natural Health Product | NPN 80113359 |
| Quality Standards | Made in Canada |
| Country | Made in Canada  |
About this item
- ENHANCED ENERGY & METABOLISM: Promotes vitality with a potent combination of vitamin B12 and folate, supporting normal metabolism for sustained energy throughout the day.
- ADVANCED METHYLATED FORMULA: Includes L-5-methyltetrahydrofolate (methylfolate), a liquid supplement designed for optimal absorption, suitable for those who need methylated B9 and B12 vitamins.
- COMPREHENSIVE B12 COMPLEX: Contains vitamin B12 (methylcobalamin) 20mcg per drop, supporting overall well-being for both men and women.
- LIQUID FOLATE CONVENIENCE: Provides the ease and accuracy of liquid drops with 200mcg of folate per drop, ideal for those who prefer an easily absorbed folate supplement.
- IMMUNE SYSTEM SUPPORT: Alongside energy benefits, this B-vitamin combination helps support normal immune function and overall health.
Product Description
B9 Folate 200mcg with Vitamin B12 20mcg - Liquid Drops for Easy Absorption
200mcg of bioactive L-5-methyltetrahydrofolate (5-MTHF) paired with 20mcg of vitamin B12 (methylcobalamin) in every natural blueberry-flavoured drop - a liquid format designed for easy, adjustable dosing across the whole family. Licensed Natural Health Product. NPN 80113359. Licensed Natural Health Product NPN 80113359.
200 mcg de L-5-méthyltétrahydrofolate (5-MTHF) bioactif, associé à 20 mcg de vitamine B12 (méthylcobalamine), dans chaque goutte à saveur naturelle de bleuet - un format liquide conçu pour un dosage facile et ajustable pour toute la famille. Produit de santé naturel homologué. NPN 80113359.
One Drop, Two Active B Vitamins
200mcg L-5-Methyltetrahydrofolate plus 20mcg Methylcobalamin B12 - Vegan, Non-GMO, Gluten-Free
Bioactive Folate, Ready to Use
L-5-methyltetrahydrofolate is the already-active form of folate - the body can use it directly, without the extra conversion step that synthetic folic acid requires.
Liquid Drops for Adjustable Dosing
An age-based drop schedule (1 to 5 drops daily) makes it easy to dose accurately across children, adolescents and adults from a single 15ml bottle.
Advanced Ingredients, Superior Results
Two active B vitamins, each playing a distinct role - here is what's inside every drop of CanPrev B9 Folate with Vitamin B12.
B9 Folate (L-5-methyltetrahydrofolate)
The bioactive, already-methylated form of folate that the body can use directly, supporting red blood cell formation and healthy metabolism.
200 mcg per drop
Vitamin B12 (methylcobalamin)
An active coenzyme form of vitamin B12 that works alongside folate in the body's methylation cycle, supporting energy metabolism and immune function.
20 mcg per dropCanPrev B9 Folate + B12: Supplement Facts
Supplement Facts
- Folate B9 (L-5-methyltetrahydrofolate) per drop200 mcg
- Vitamin B12 (methylcobalamin) per drop20 mcg
Non-Medicinal Ingredients: Non-medicinal ingredients: Purified water, natural blueberry flavour, natural flavour, glycerin, potassium phosphate, potassium sorbate, sodium hydroxide, disodium EDTA, stevia.
Recommended Use or Purpose: Helps to prevent folate (vitamin B9) deficiency and to form red blood cells. Helps to maintain a healthy metabolism and normal function of the immune system. Helps to reduce the risk of neural tube defects when taken daily at least three months prior to becoming pregnant and during early pregnancy.
Recommended Dose: Children 1-3 years: 1 drop daily. Children 4-8 years: 2 drops daily. Adolescents 9-13 years: 3 drops daily. Adolescents 14-18 years: 4 drops daily. Adults 19 years and older: 5 drops daily, or as directed by a qualified health care practitioner. Shake well before use.
Cautions and Warnings: Consult a health care practitioner prior to use. Keep out of reach of children. Do not use if the safety seal is broken. Women who are or may become pregnant should ensure adequate folate intake through diet and/or supplementation, as directed by a health care practitioner.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Fiche produit
- Folate B9 (L-5-méthyltétrahydrofolate) par goutte200 mcg
- Vitamine B12 (méthylcobalamine) par goutte20 mcg
Ingrédients non médicinaux : Ingrédients non médicinaux : Eau purifiée, arôme naturel de bleuet, arôme naturel, glycérine, phosphate de potassium, sorbate de potassium, hydroxyde de sodium, EDTA de sodium, stevia.
Usage ou fins recommandés : Aide à prévenir une carence en folate (vitamine B9) et à la formation des globules rouges. Aide à maintenir un métabolisme en santé et le fonctionnement normal du système immunitaire. Aide à réduire les risques de malformations du tube neural lorsqu'il est pris quotidiennement au moins trois mois avant le début de la grossesse et pendant le début de la grossesse.
Posologie recommandée : Enfants de 1 à 3 ans : 1 goutte par jour. Enfants de 4 à 8 ans : 2 gouttes par jour. Adolescents de 9 à 13 ans : 3 gouttes par jour. Adolescents de 14 à 18 ans : 4 gouttes par jour. Adultes de 19 ans et plus : 5 gouttes par jour, ou selon les directives d'un professionnel de la santé qualifié. Bien agiter avant usage.
Mises en garde : Consulter un professionnel de la santé avant l'usage. Garder hors de la portée des enfants. Ne pas utiliser si le sceau de sécurité est brisé. Les femmes enceintes ou qui pourraient le devenir devraient s'assurer d'un apport adéquat en folate par l'alimentation et/ou la supplémentation, selon les directives d'un professionnel de la santé.
NPN 80113359
Support healthy metabolism, red blood cell formation & immune function
Get CanPrev B9 Folate with Vitamin B12 drops on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev B9 Folate with Vitamin B12
200mcg L-5-MTHF folate plus 20mcg methylcobalamin B12 in easy liquid drops - premium CanPrev quality.
Bioactive 5-MTHF folate
200mcg of L-5-methyltetrahydrofolate per drop - the already-active form of folate, ready for the body to use.
Paired with methylcobalamin B12
20mcg of vitamin B12 (methylcobalamin) per drop, working alongside folate in the body's methylation and red-blood-cell pathways.
Liquid drops, not capsules
Blueberry-flavoured liquid drops with an adjustable, age-based dose from a single 15ml bottle - no capsules to swallow.
Vegan, made in Canada
Vegan, non-GMO, gluten-free formula - a licensed Natural Health Product made in Canada. NPN 80113359.
Inside every drop
200mcg of L-5-methyltetrahydrofolate (bioactive folate) plus 20mcg of vitamin B12 (methylcobalamin) in a natural blueberry-flavoured liquid drop.
How to use it
Shake well, then dispense with the dropper
Shake the bottle well before use. Fill the dropper and dispense drops directly into the mouth, or add to food or a beverage.
Follow the age-based daily dose
Children 1-3 years: 1 drop daily. Children 4-8 years: 2 drops daily. Adolescents 9-13 years: 3 drops daily. Adolescents 14-18 years: 4 drops daily. Adults 19 years and older: 5 drops daily, or as directed by a health care practitioner.
Take consistently, at the same time each day
For steady daily folate and B12 intake, take your dose at a consistent time - directly under the tongue or mixed into food or a drink.
Consult a health care practitioner before use
Talk to a health care practitioner before use, especially if pregnant, breastfeeding, or planning pregnancy, to confirm the right daily folate intake for your needs.
What the research says about folate and vitamin B12
Educational summaries of published research on folate (B9) and vitamin B12; not product-specific claims. CanPrev B9 Folate with Vitamin B12's claim is the authorized use under NPN 80113359.
Comparable bioavailability to folic acid, plus practical advantages
A review of clinical pharmacokinetics found L-5-methyl-THF has bioavailability and physiological activity comparable to folic acid at equimolar doses, with two practical advantages: reduced potential for masking vitamin B12 deficiency symptoms, and less interaction with drugs that inhibit dihydrofolate reductase.
ReviewHigher plasma folate peaks than folic acid in a crossover trial
In a randomized, double-blind, crossover study, a single oral dose of (6S)-5-methyl-THF produced significantly higher plasma folate area-under-curve and peak concentration than an equimolar dose of folic acid, with only folic acid causing a transient rise in unmetabolized folic acid in the blood.
Human RCT16-week study finds L-5-methyl-THF a more reliable reference folate
A 16-week placebo-controlled intervention in 163 healthy adults measuring plasma and erythrocyte folate response concluded that (6S)-5-methyltetrahydrofolic acid, rather than folic acid, should be used as the reference standard for assessing folate bioavailability in longer-term studies.
Human RCTMTHFR genetics and B12 status shape how folate affects pregnancy
A 2026 review describes how methylenetetrahydrofolate reductase (MTHFR) gene variants and vitamin B12 levels are critical modifiers of folate metabolism, influencing how folic acid supplementation relates to pregnancy outcomes beyond neural tube defect prevention.
ReviewActive folate recommended for women with MTHFR mutations
A clinical review of preconception and prenatal nutrition notes that active folates such as 5-MTHF are particularly relevant for women with MTHFR mutations, who may have difficulty converting standard folic acid into its active form.
Review5-methyltetrahydrofolate's role in the body's methylation cycle
A laboratory-medicine review explains that 5-methyltetrahydrofolate, the main folate form found in blood, is required for the vitamin B12-dependent enzyme methionine synthase to convert homocysteine back to methionine - linking folate and B12 status directly to homocysteine levels.
ReviewPericonceptional folic acid linked to an 80% drop in neural tube defects
A review of folic acid supplementation policy across four European countries reports that randomized trials have shown periconceptional folic acid supplementation reduces the incidence of neural tube defects by nearly 80%, supporting the recommendation that women of reproductive age take 400 mcg of folic acid daily.
ReviewUmbrella review: a 57% reduction in neural tube defects
An umbrella review pooling 10 systematic reviews and meta-analyses (296,816 participants) found prenatal folic acid and/or multivitamin supplementation was associated with a 57% overall reduction in neural tube defects, with a larger effect specifically from folic acid.
Umbrella reviewCochrane review: iron plus folic acid supports maternal and infant outcomes
A Cochrane systematic review of 57 trials in nearly 49,000 women found daily oral iron plus folic acid supplementation during pregnancy probably reduces maternal anemia at term and is linked to higher infant birthweight compared with placebo.
Meta-analysisA case study shows how quickly B12 status can decline without supplementation
A closely monitored case study of a long-term vegan found that after stopping methylcobalamin supplementation, his B12 and holotranscobalamin levels gradually declined, with supplementation needing to be reintroduced after 16 weeks as homocysteine rose.
Case studyHigher-dose methylcobalamin improved maternal B12 status and infant development
In the MATCOBIND randomized trial of 531 vegetarian mothers, daily supplementation with 250 mcg of methylcobalamin during pregnancy and post-partum produced a significantly larger rise in maternal vitamin B12 and holotranscobalamin levels, and higher infant mental development scores, than a 50 mcg dose.
Human RCTB9 and B12's distinct roles in brain nutrition, reviewed
A review of nutrients and brain function describes vitamin B9 (folate) as protective for brain development and memory during aging, while vitamin B12 supplementation is described as supporting cerebral and cognitive function in older adults, particularly frontal-lobe-related tasks.
ReviewA case linking B12 deficiency to disrupted red blood cell production
A case report describes a patient with pernicious anemia (an autoimmune cause of vitamin B12 deficiency) presenting with macrocytosis and hypersegmented neutrophils - hallmark signs of the ineffective red blood cell formation that characterizes B12 deficiency.
Case reportB12's necessity for a normal red-blood-cell response, shown in animal research
In vitamin B12-deficient rats exposed to low oxygen to stimulate red blood cell production, the expected rise in erythrocyte count failed to occur - evidence that adequate B12 is necessary for the body's normal erythropoietic response.
Animal studyFolic acid's effect on red blood cell folate measured in a crossover trial
A randomized crossover trial in children measured red blood cell folate concentrations before and after a period of daily folic acid supplementation versus placebo, using RBC folate as the primary marker of the body's folate status over time.
Human RCTB-vitamin intake linked to cardiovascular risk in a large review
An updated systematic review and meta-analysis found that higher intakes of folic acid, vitamin B6 and vitamin B12 were generally associated with a lower risk of cardiovascular disease in the general population, with folic acid supplementation also shown to reduce carotid intima-media thickness.
Meta-analysisAn umbrella review supports folic acid for lowering homocysteine-related stroke risk
A large umbrella review of 135 observational meta-analyses and 26 interventional meta-analyses concluded that homocysteine is a causal risk factor for stroke, and that homocysteine-lowering with folic acid was validated by interventional meta-analyses as reducing stroke risk.
Umbrella reviewMeta-analysis: vitamin B supplementation and recurrent stroke
A meta-analysis of 7 randomized trials in nearly 9,850 stroke patients found vitamin B supplementation (including folate and B12) was associated with a significantly lower rate of recurrent stroke and a meaningful reduction in plasma homocysteine levels.
Meta-analysisHigher folate and B12 correlated with better attention and memory
In a study of 639 people across different age groups, higher folate and vitamin B12 levels were significantly correlated with lower homocysteine and with better performance on attention-span and delayed memory-recall tests.
Observational studyOne-carbon metabolism examined in recurrent depression
A study comparing 137 people with recurrent major depression to 73 healthy controls measured homocysteine, folate and vitamins B6/B12 alongside markers of fatty-acid metabolism, exploring the overlap between one-carbon metabolism and the cardiovascular risk often seen alongside depression.
Case-control studyB-vitamin gene variants linked to mood and cognitive decline research
A review of B-vitamin-related gene variants (including MTHFR) found associations between these polymorphisms and increased incidence of neurodevelopmental, psychiatric and cognitive-decline conditions, underscoring folate and B12's roles in nervous-system function.
ReviewWhy this formula pairs folate with B12: a safety consideration
A clinical review notes that in the past, high-dose folic acid (over 5 mg/day) was used to reverse the anemia of vitamin B12 deficiency, but this can mask the underlying B12 deficiency - the authors recommend increased vigilance for B12 deficiency in anyone taking supplemental folic acid.
ReviewMTHFR variant, elevated homocysteine and stroke risk in young adults
A systematic review of 11 studies in young adults found the MTHFR C677T gene variant is closely associated with elevated homocysteine, a contributor to under-diagnosed ischemic stroke, and noted this risk can be mitigated with simple vitamin B12 and folate supplementation.
Systematic reviewMethylcobalamin among current options studied for diabetic nerve health
A 2026 review of diabetic neuropathy mechanisms and treatments lists methylcobalamin, alongside agents like alpha-lipoic acid and gabapentin, among the pharmacological options currently used to help address the nerve dysfunction and pain of this condition.
ReviewFrequently asked questions
What is CanPrev B9 Folate with Vitamin B12 drops and what does it do?
It's a liquid supplement providing 200mcg of B9 folate (as L-5-methyltetrahydrofolate) and 20mcg of vitamin B12 (as methylcobalamin) per drop. It helps to prevent folate deficiency, helps form red blood cells, helps maintain a healthy metabolism, supports immune function, and helps reduce the risk of neural tube defects when taken daily at least three months before becoming pregnant and during early pregnancy.
How many drops do I take?
Dose is based on age: children 1-3 years take 1 drop daily, children 4-8 years take 2 drops daily, adolescents 9-13 years take 3 drops daily, adolescents 14-18 years take 4 drops daily, and adults 19 years and older take 5 drops daily, or as directed by a health care practitioner.
Why L-5-methyltetrahydrofolate instead of folic acid?
L-5-methyltetrahydrofolate (5-MTHF) is the active, already-methylated form of folate that the body normally circulates and uses directly, without needing the extra conversion step that synthetic folic acid requires.
Why does it include vitamin B12?
Folate and vitamin B12 work together in the body's methylation cycle. B12 (as methylcobalamin) is included alongside 200mcg of folate to support red blood cell formation and healthy metabolism.
Is it suitable for children?
Yes - the label provides age-specific dosing from age 1 upward. Children 1-3 years take 1 drop daily; consult a health care practitioner to confirm the right dose for your child.
Is it vegan and allergen-friendly?
Yes - the formula is vegan and free from gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours, preservatives and animal products.
How long does one bottle last?
Each 15ml bottle provides 450 drops. At the adult dose of 5 drops daily, that's a 90-day supply.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Support healthy metabolism, red blood cell formation & immune function
Get CanPrev B9 Folate with Vitamin B12 drops on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80113359. B9 Folate with Vitamin B12 drops help to prevent folate deficiency, help form red blood cells, help maintain a healthy metabolism, and support immune function - and help reduce the risk of neural tube defects when taken daily at least three months prior to becoming pregnant and during early pregnancy. The research summaries below concern folate and vitamin B12 generally and are educational - they are not claims about this finished product. Consult a health care practitioner prior to use. Read and follow the label. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a health care practitioner prior to use. Keep out of reach of children. Do not use if the safety seal is broken. Women who are or may become pregnant should ensure adequate folate intake through diet and/or supplementation, as directed by a health care practitioner.
Indications
Recommended Use or Purpose: Helps to prevent folate (vitamin B9) deficiency and to form red blood cells. Helps to maintain a healthy metabolism and normal function of the immune system. Helps to reduce the risk of neural tube defects when taken daily at least three months prior to becoming pregnant and during early pregnancy.
Ingredients
Medicinal Ingredients (per drop): Folate B9 (L-5-methyltetrahydrofolate) 200 mcg, Vitamin B12 (methylcobalamin) 20 mcg. Non-medicinal ingredients: Purified water, natural blueberry flavour, natural flavour, glycerin, potassium phosphate, potassium sorbate, sodium hydroxide, disodium EDTA, stevia. Vegan. GMO-free. No gluten, dairy, soy, wheat, yeast, sugar, artificial colours, flavours, preservatives or animal products. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.
Directions
Recommended Dose: Children 1-3 years: 1 drop daily. Children 4-8 years: 2 drops daily. Adolescents 9-13 years: 3 drops daily. Adolescents 14-18 years: 4 drops daily. Adults 19 years and older: 5 drops daily, or as directed by a qualified health care practitioner. Shake well before use.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.