CanPrev Alpha Lipoic Acid 600mg - Antioxidant Support | 60 Vegan Caps
Visit the CanPrev Store Read all reviews on Amazon →| Brand | CanPrev |
| Serving | 1 capsule (600 mg ALA) |
| Licensed Natural Health Product | NPN 80029600 |
| Quality Standards | Made in Canada |
| Country | Made in Canada  |
About this item
- 600MG ALPHA LIPOIC ACID PER CAPSULE: A therapeutic 600 mg dose of alpha lipoic acid (ALA) in a highly stable DL-ALA form - one of the few antioxidants that is both fat- and water-soluble.
- WITH VITAMIN B1 & BIOTIN: Formulated with 20 mg thiamine (vitamin B1) and 200 mcg biotin, nutrients that can be depleted or compete with ALA for cellular uptake at higher doses.
- HELPS PROMOTE HEALTHY GLUCOSE METABOLISM: Alpha lipoic acid helps to promote healthy glucose metabolism, supporting the body's ability to use energy efficiently.
- PROVIDES ANTIOXIDANTS FOR GOOD HEALTH: A source of antioxidants for the maintenance of good health, helping protect cells from oxidative stress.
- SIMPLE ONCE-DAILY CAPSULE: Just one vegan capsule per day - a 60-capsule bottle provides a full 60-day supply.
- CLEAN VEGAN FORMULA: Vegan capsules free from GMOs, gluten, soy and dairy, with no artificial colours or fillers.
- PREMIUM CANADIAN QUALITY: Formulated and manufactured in Canada by CanPrev, licensed under Health Canada NPN 80029600.
Product Description
Alpha Lipoic Acid 600 - Antioxidant & Glucose Metabolism Support
A therapeutic 600 mg dose of alpha lipoic acid (ALA) in a highly stable DL-ALA form - one of the few antioxidants that is both fat- and water-soluble, helping it reach every part of the cell. Formulated with vitamin B1 and biotin to help offset the nutrient competition that can occur at higher ALA doses. Licensed Natural Health Product NPN 80029600.
Une dose thérapeutique de 600 mg d'acide alpha-lipoïque (AAL), sous une forme DL-AAL stable et sécuritaire - l'un des seuls antioxydants à la fois soluble dans l'eau et dans les graisses, ce qui lui permet de pénétrer dans toutes les parties de la cellule. Formulé avec de la vitamine B1 et de la biotine. Produit de santé naturel homologué. NPN 80029600.
One Capsule, Full-Spectrum Antioxidant Support
600mg DL-Alpha Lipoic Acid plus Vitamin B1 & Biotin - Vegan, Non-GMO, Gluten-Free
Fat- & Water-Soluble Antioxidant
Alpha lipoic acid is one of the few antioxidants that dissolves in both fat and water, letting it cross cell membranes that many other antioxidants cannot reach.
Formulated to Offset Nutrient Competition
20 mg of vitamin B1 (thiamine) and 200 mcg of biotin are included because high-dose ALA can compete with these nutrients for absorption into cells.
What Alpha Lipoic Acid 600 Supports
Alpha lipoic acid is studied for a range of roles in cellular antioxidant defense and metabolism - here is what CanPrev Alpha Lipoic Acid 600 is formulated to support.
Antioxidant Function
Helps protect cells from oxidative stress as a source of antioxidants for the maintenance of good health.
Healthy Glucose Metabolism
Helps to promote healthy glucose metabolism.
Cellular Energy Support
Acts as a cofactor supporting the body's mitochondrial energy-producing pathways.
Nerve & Circulatory Comfort
Widely studied for its role in supporting nerve function and healthy blood flow.
CanPrev Alpha Lipoic Acid: Supplement Facts
Supplement Facts
- DL-Alpha Lipoic Acid per capsule600 mg
- Vitamin B1 (Thiamine) per capsule20 mg
- Biotin per capsule200 mcg
Non-Medicinal Ingredients: Non-medicinal ingredients: Microcrystalline cellulose, hypromellose (capsule), magnesium stearate.
Recommended Use or Purpose: Helps to promote healthy glucose metabolism. Source of antioxidants for the maintenance of good health.
Recommended Dose (Adults 19 years and older): Take 1 capsule daily, or as directed by a qualified health care practitioner.
Cautions and Warnings: Consult a health care practitioner prior to use if you are pregnant, breastfeeding, or diabetic. Stop use and consult a health care practitioner if you experience sweating, paleness, chills, headache, dizziness or confusion - these may be symptoms of hypoglycemia (low blood sugar). Do not use if the safety seal is broken. Keep out of reach of children.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Fiche produit
- Acide DL-alpha-lipoïque par capsule600 mg
- Vitamine B1 (thiamine) par capsule20 mg
- Biotine par capsule200 mcg
Ingrédients non médicinaux : Ingrédients non médicinaux : Cellulose microcristalline, hypromellose (capsule), stéarate de magnésium.
Usage ou fins recommandés : Aide à favoriser un métabolisme sain du glucose. Source d'antioxydants pour le maintien d'une bonne santé.
Posologie recommandée (adultes de 19 ans et plus) : Prendre 1 capsule par jour, ou selon les directives d'un professionnel de la santé qualifié.
Mises en garde : Consulter un professionnel de la santé avant l'usage si vous êtes enceinte, si vous allaitez ou si vous êtes diabétique. Cesser l'utilisation et consulter un professionnel de la santé si vous éprouvez de la transpiration, de la pâleur, des frissons, des maux de tête, des étourdissements ou de la confusion - ces symptômes pourraient indiquer une hypoglycémie. Ne pas utiliser si le sceau de sécurité est brisé. Garder hors de la portée des enfants.
NPN 80029600
Support healthy glucose metabolism & antioxidant balance
Get CanPrev Alpha Lipoic Acid 600 on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy CanPrev Alpha Lipoic Acid 600
A therapeutic 600mg dose of stable DL-ALA, formulated with B1 and biotin - premium CanPrev quality.
Therapeutic 600mg dose
A clinically relevant 600 mg dose of alpha lipoic acid in a highly stable DL-ALA form.
Antioxidant & glucose metabolism
Helps promote healthy glucose metabolism and provides antioxidants for the maintenance of good health.
Formulated with B1 & biotin
Includes vitamin B1 and biotin to help offset nutrient competition at higher ALA doses.
Premium Canadian brand
CanPrev - Pro Essentials line, formulated and made in Canada. NPN 80029600.
How to use it
Take 1 capsule daily
Adults (19 years and older) take one capsule daily, or as directed by a qualified health care practitioner.
With food
Take with a meal for comfort, or as directed by a health care practitioner.
Watch for low blood sugar signs
Discontinue use and consult a health care practitioner if you notice sweating, paleness, chills, headache, dizziness or confusion.
Ask a professional if pregnant, breastfeeding or diabetic
Consult a health care practitioner before use if you are pregnant, breastfeeding, or living with diabetes.
What the research says about alpha lipoic acid
Educational summaries of published research on alpha-lipoic acid (ALA); not product-specific claims. CanPrev Alpha Lipoic Acid 600's claim is the authorized use under NPN 80029600.
Recycles other antioxidants back to work
In skin tissue, the reduced form of alpha-lipoic acid (dihydrolipoate) regenerated a vitamin E-type antioxidant faster and more effectively than glutathione, once vitamin C was also present.
MechanismA dual-solubility antioxidant that corrects blood-flow deficits
A review of antioxidant treatments in experimental diabetes describes alpha-lipoic acid, alongside agents like vitamin E, as correcting nerve blood-flow deficits caused by reactive oxygen species.
ReviewLower oxidative stress markers in a human trial
Two weeks of intravenous alpha-lipoic acid lowered oxidative stress markers (malondialdehyde, 8-iso-prostaglandin) and inflammatory markers (TNF-alpha, IL-6) in obese adults with impaired glucose tolerance.
Human RCTAntioxidant and mitochondrial protection, reviewed
A 2026 review attributes alpha-lipoic acid's effects in diabetic neuropathy to antioxidant activity, mitochondrial protection and improved microvascular function.
ReviewAn essential mitochondrial cofactor
Lipoic acid is described as an essential cofactor for several mitochondrial enzyme complexes (including pyruvate dehydrogenase) that are central to how cells convert fuel into energy.
ReviewSynergy with other protective pathways
In diabetic rats, combining a PKC-beta inhibitor with antioxidants including alpha-lipoic acid (or with gamma-linolenic acid) fully corrected nerve conduction and blood-flow deficits, showing synergy between these mechanisms.
Animal studyAn antioxidant-fatty-acid conjugate outperformed omega-3s
At matched low doses in diabetic rats, a gamma-linolenic acid-lipoic acid conjugate more fully prevented nerve conduction and blood-flow decline than DHA-enriched phospholipids.
Animal studyAttenuated nerve decline in an obesity/diabetes model
In Zucker diabetic fatty rats, alpha-lipoic acid treatment attenuated the decline in motor and sensory nerve conduction velocity seen with progressive diabetes.
Animal studyThe SYDNEY trial: fewer neuropathic symptoms
In a randomized, placebo-controlled trial, five days a week of intravenous alpha-lipoic acid (600 mg) significantly improved pain, numbness and prickling symptom scores in diabetic polyneuropathy versus placebo.
Human RCTA well-tolerated ancillary option, reviewed
A review of randomized trials and meta-analyses concludes alpha-lipoic acid is efficacious and safe for diabetic neuropathy, with a more rapid onset than some licensed analgesics.
ReviewLower symptom scores across pooled trials
A network meta-analysis of 11 studies found alpha-lipoic acid 600 mg/day produced a significantly lower Total Symptom Score than placebo in adults with diabetic peripheral neuropathy.
Meta-analysisImproved nerve conduction in an animal model
In diabetic rats, DL-alpha-lipoic acid improved sensory nerve conduction velocity, corrected nutritive nerve blood flow and increased the mitochondrial oxidative state.
Animal studyImproved glucose disposal after 10 days
In a pilot study, ten days of intravenous thioctic (alpha-lipoic) acid increased insulin-stimulated glucose disposal by about 30% in patients with type 2 diabetes.
Human pilot studyOral dosing also improved insulin sensitivity
A placebo-controlled pilot trial found 4 weeks of oral alpha-lipoic acid (600-1,800 mg/day) improved insulin-stimulated glucose disposal by 27% versus placebo in type 2 diabetes, with no added benefit at higher doses.
Human RCTA neutral result on weight in a 6-week trial
In people with type 2 diabetes and neuropathy, 6 weeks of 600 mg/day oral alpha-lipoic acid produced a slight, non-significant weight reduction and no significant change in adiponectin or other metabolic markers.
Human RCTImproved blood flow and lipid risk factors in diabetic rats
In diabetic rats, alpha-lipoic acid corrected nerve blood-flow and conduction deficits and significantly lowered triglycerides and clotting-risk markers (fibrinogen, factor VII, von Willebrand factor).
Animal studyExplored in a heart-injury model
In a mouse myocardial infarction model, alpha-lipoic acid reduced oxidative stress and a senescence-associated inflammatory signature in heart macrophages, easing injury after simulated heart attack.
Preclinical studyNo measurable cognition change in a small pilot
In a 12-week open-label pilot in adults over 80 without dementia, daily alpha-lipoic acid was well tolerated but showed no statistically significant effect on cognitive function, executive function or mood.
Human pilot studyStudied alongside standard neuropathy medications
In diabetic neuropathy patients already taking gabapentin or pregabalin, adding alpha-lipoic acid was evaluated for its effect on platelet aggregation in a randomized, placebo-controlled study.
Human RCTPart of a combination approach studied in PCOS
In obese women with polycystic ovary syndrome, a combination of metformin, myo-inositol and alpha-lipoic acid improved hyperandrogenism, BMI and insulin-resistance index measures compared with metformin alone.
Human RCTA recognized, though rare, hypoglycemia risk
A case series of six patients linked recurrent hypoglycemia to insulin autoimmune syndrome (Hirata syndrome), most cases traced to alpha-lipoic acid in multivitamin supplements.
Case seriesTwo more documented cases
Two patients taking a multivitamin containing alpha-lipoic acid developed recurrent hypoglycemia from insulin autoimmune syndrome, resolving after stopping the supplement and adjusting diet.
Case reportsSymptoms resolved after stopping the supplement
A 36-year-old man taking alpha-lipoic acid as part of a multivitamin developed recurrent low blood sugar from insulin autoimmune syndrome, which was managed successfully once the supplement was identified and stopped.
Case reportA genetic susceptibility marker identified
Two new cases of alpha-lipoic-acid-triggered insulin autoimmune syndrome were both linked to a specific HLA gene variant (HLA-DRB1*04:03), helping explain why this rare reaction affects only some people.
Case reportsFrequently asked questions
What is CanPrev Alpha Lipoic Acid 600 and what does it do?
It's a 600 mg dose of DL-alpha lipoic acid (ALA) per vegan capsule, formulated with vitamin B1 and biotin. ALA helps to promote healthy glucose metabolism and is a source of antioxidants for the maintenance of good health.
How do I take it?
Adults 19 years and older take 1 capsule daily, or as directed by a qualified health care practitioner.
Why does it include vitamin B1 and biotin?
High doses of alpha lipoic acid can compete with thiamine (vitamin B1) and biotin for absorption into cells, or deplete these nutrients over time - this formula includes both to help offset that.
How long does one bottle last?
Each bottle contains 60 vegan capsules - at the recommended dose of 1 capsule daily, that's a full 60-day supply.
Is it vegan?
Yes - both the DL-alpha lipoic acid and the vegetable capsule are vegan, with a clean formula free of GMOs, gluten, soy and dairy.
Who should use caution, or not use it?
Consult a health care practitioner before use if you are pregnant, breastfeeding, or diabetic. Discontinue use and consult a practitioner if you experience sweating, paleness, chills, headache, dizziness or confusion - possible signs of low blood sugar.
Where do I buy it?
Use the orange button on this page - it takes you to the CanPrev listing on Amazon.ca for secure checkout and fast delivery.
Support healthy glucose metabolism & antioxidant balance
Get CanPrev Alpha Lipoic Acid 600 on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80029600. Alpha Lipoic Acid helps to promote healthy glucose metabolism and is a source of antioxidants for the maintenance of good health. The research summaries below concern alpha-lipoic acid generally and are educational - they are not claims about this finished product. Read and follow the label. Consult a health care practitioner before use if you are pregnant, breastfeeding or diabetic; discontinue use and consult a practitioner if symptoms of low blood sugar occur. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a health care practitioner prior to use if you are pregnant, breastfeeding, or diabetic. Stop use and consult a health care practitioner if you experience sweating, paleness, chills, headache, dizziness or confusion - these may be symptoms of hypoglycemia (low blood sugar). Do not use if the safety seal is broken. Keep out of reach of children.
Indications
Recommended Use or Purpose: Helps to promote healthy glucose metabolism. Source of antioxidants for the maintenance of good health.
Ingredients
Medicinal ingredients (per capsule): DL-Alpha lipoic acid 600 mg, Vitamin B1 (thiamine) 20 mg, Biotin 200 mcg. Non-medicinal ingredients: Microcrystalline cellulose, hypromellose (capsule), magnesium stearate. NMIs are subject to change - always read and follow the label for accurate ingredients, cautions and allergen information.
Directions
Recommended Dose (Adults 19 years and older): Take 1 capsule daily, or as directed by a qualified health care practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.