AOR Berberine 500mg - Cholesterol & Lipid Support | 60-120ct
Visit the AOR Store| Brand | AOR |
| Serving | 500 mg (1 capsule) |
| Licensed Natural Health Product | NPN 80123625 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- HEALTHY LDL CHOLESTEROL & LIPID LEVELS: 500 mg of berberine per capsule to help support healthy lipid levels and LDL cholesterol as part of a heart-conscious routine.
- CARDIOVASCULAR HEALTH & TRIGLYCERIDES: Supports cardiovascular health and helps maintain healthy triglyceride levels alongside a balanced diet and active lifestyle.
- HOLISTIC CARDIOVASCULAR SUPPORT: A single-ingredient formula built for holistic, whole-body cardiovascular support - not a one-note lipid product.
- EASY, CONVENIENT DAILY DOSING: An easy-to-swallow vegan capsule fits into a simple twice-daily routine - no powders to mix, no awkward serving sizes.
- SCIENCE-BACKED, CUSTOMER-TRUSTED FORMULA: Formulated on a foundation of peer-reviewed berberine research, with strong customer satisfaction for lipid and cardiovascular support.
- TWO SIZES FOR YOUR ROUTINE: Available as a 60-capsule (30-day) or 120-capsule (60-day) supply, both the same 500 mg berberine formula, so you can stock up and save trips.
- PREMIUM CANADIAN QUALITY: Made in Canada in a GMP-compliant facility by Advanced Orthomolecular Research (AOR), licensed under Health Canada NPN 80123625.
Berberine, Backed by Research
AOR Berberine 500mg
500 mg of pure berberine per capsule to help support healthy lipid levels, LDL cholesterol and cardiovascular health. Licensed Natural Health Product NPN 80123625.
AOR Berberine 500mg
A single well-studied compound, dosed at 500 mg per capsule, for holistic cardiovascular and lipid support.
Healthy Lipid Levels
Helps support healthy LDL cholesterol and lipid levels as part of a heart-conscious routine.
Cardiovascular Health
Supports cardiovascular health and healthy triglyceride levels for holistic heart support.
Easy Daily Dosing
An easy-to-swallow vegan capsule - simple to fit into a twice-daily routine.
Why AOR Berberine
Berberine is one of the most extensively studied plant compounds in modern metabolic health research - explored for its effects on lipid levels, cardiovascular risk markers and glucose metabolism.
Healthy LDL Cholesterol
Helps support healthy lipid levels and LDL cholesterol.
Triglyceride Support
Helps maintain healthy triglyceride levels for a balanced lipid profile.
Holistic Cardiovascular Support
Supports overall cardiovascular health, not just a single lipid marker.
Easy, Convenient Dosing
An easy-to-swallow vegan capsule fits into a simple daily routine.
Science-Backed Formula
Formulated on a foundation of peer-reviewed berberine research.
Premium Canadian Quality
Made in Canada in a GMP-compliant facility, Health Canada NPN licensed.
AOR Berberine: Supplement Facts
Each capsule contains:
- Berberine500 mg
Non-Medicinal Ingredients: Carrot Root Powder, Hypromellose, Maltodextrin, Microcrystalline Cellulose, Silicon Dioxide, Sodium Stearyl Fumarate.
Recommended Use or Purpose: Helps support healthy lipid levels (i.e. total cholesterol, LDL cholesterol and triglycerides). Helps to maintain and support cardiovascular health.
Recommended Dose (Adults 18 years and older): Take 1 capsule 2 times a day with food, or as directed by a health care practitioner. Do not exceed the recommended dose unless instructed by a health care practitioner. Consult a health care practitioner for use beyond 3 months. Do not open capsules, as this may compromise the stability of the medicinal ingredients.
Cautions and Warnings: Consult a health care practitioner prior to use if you have a kidney disorder, have diabetes, cardiovascular disease, liver or kidney disease, gall stones, a blood disorder or leucopenia, hypoglycemia, hypotension, or if you are taking prescription medication as this may alter the effectiveness of these medications. If you experience sweating, paleness, chills, headache, dizziness and/or confusion, discontinue use and consult a health care practitioner. Do not use if you are pregnant, breastfeeding, or plan to become pregnant. May cause additional gastrointestinal upsets such as constipation, vomiting and abdominal pain/cramps, in which case discontinue use and consult a health care practitioner. Some people may experience skin irritation, facial flushing and slowed heart rate.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Chaque capsule contient :
- Berbérine500 mg
Ingrédients non médicinaux : Poudre de racine de carotte, Hypromellose, Maltodextrine, Cellulose microcristalline, Dioxyde de silicium, Stéarylfumarate de sodium.
Usage ou fins recommandés : Aide à soutenir des niveaux de lipides sains (c.-à-d. le cholestérol total, le cholestérol LDL et les triglycérides). Aide à maintenir et à soutenir la santé cardiovasculaire.
Dose recommandée (adultes de 18 ans et plus) : Prendre 1 capsule 2 fois par jour avec de la nourriture, ou selon les directives d'un praticien de soins de santé. Ne pas dépasser la dose recommandée sauf sur indication d'un praticien de soins de santé. Consultez un praticien de soins de santé pour une utilisation au-delà de 3 mois. Ne pas ouvrir les capsules, car cela pourrait compromettre la stabilité des ingrédients médicinaux.
Mises en garde et précautions : Consultez un praticien de soins de santé avant l'utilisation si vous avez un trouble rénal, si vous avez le diabète, une maladie cardiovasculaire, une maladie du foie ou des reins, des calculs biliaires, un trouble sanguin ou une leucopénie, une hypoglycémie, une hypotension, ou si vous prenez des médicaments d'ordonnance, car cela pourrait modifier l'efficacité de ces médicaments. Si vous ressentez de la transpiration, une pâleur, des frissons, des maux de tête, des étourdissements et/ou de la confusion, cessez l'utilisation et consultez un praticien de soins de santé. Ne pas utiliser si vous êtes enceinte, si vous allaitez, ou prévoyez le devenir. Peut causer des troubles gastro-intestinaux additionnels tels que constipation, vomissements et douleurs/crampes abdominales, auquel cas cessez l'utilisation et consultez un praticien de soins de santé. Certaines personnes peuvent ressentir une irritation cutanée, des rougeurs faciales et un ralentissement du rythme cardiaque.
NPN 80123625
Support healthy cholesterol & cardiovascular health the easy way
Get AOR Berberine on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy AOR Berberine
One well-studied compound - four ways it supports metabolic and cardiovascular health.
LDL & Lipid Balance
Supports healthy LDL cholesterol and overall lipid levels as part of a heart-conscious routine.
Triglyceride Support
Helps maintain healthy triglyceride levels alongside diet and lifestyle.
Cardiovascular Wellness
Supports holistic cardiovascular health, not just a single lipid marker.
Backed by Modern Research
Berberine is one of the most-studied plant compounds in metabolic health research, with a large and growing body of clinical literature.
How to use
Take with food
Take 1 capsule (500 mg) with food.
Twice daily
Take a second capsule with another meal - 2 times per day total, or as directed by a health care practitioner.
Stay consistent
Take daily for consistent support. Consult a health care practitioner before using for more than 3 months.
Choose your supply
Pick the 60-capsule (30-day) or 120-capsule (60-day) bottle to match your routine.
What the research says about berberine
Peer-reviewed studies and reviews on the compound berberine - shared for education, not as claims about this finished product and not a suggestion that berberine substitutes for any prescription medication. AOR Berberine's claims are the statements authorized under its Natural Health Product licence, NPN 80123625.
A cholesterol pathway distinct from statins
A landmark study identified berberine as a cholesterol-lowering compound that upregulates liver LDL-receptor activity through a mechanism researchers describe as distinct from how statin drugs work.
Mechanistic + human studyMeta-analysis of dyslipidemia trials
A systematic review and meta-analysis of randomized controlled trials evaluated berberine's efficacy and safety in patients with dyslipidemia (unhealthy blood lipid levels).
Systematic review & meta-analysisComparing nutraceuticals for LDL
A network meta-analysis compared the LDL-cholesterol-lowering effects of several nutraceuticals, including berberine, across the published trial evidence.
Network meta-analysisMetabolic profile in type 2 diabetes
A systematic review and meta-analysis examined berberine's effect on metabolic profile markers, including triglycerides and other lipids, in adults with type 2 diabetes.
Systematic review & meta-analysisLipid profile alongside fasting glucose
A clinical study measured berberine's effect on lipid profile, liver enzymes, and fasting blood glucose in patients with nonalcoholic fatty liver disease.
Human RCTFunctional foods for cholesterol management
A 2025 review surveyed functional foods and nutraceutical ingredients - including berberine - studied for cholesterol-lowering mechanisms and efficacy.
ReviewGlycemic effects in type 2 diabetes
An early clinical trial found berberine improved fasting blood glucose and haemoglobin A1c over a 3-month period in adults with type 2 diabetes.
Human RCTA well-studied carbohydrate-metabolism compound
A review describes berberine's impact on carbohydrate metabolism, including support for pancreatic beta-cell function and peripheral insulin sensitivity via GLUT-1 and GLUT-4 activity.
ReviewInsulin sensitizer in metabolic studies
A clinical trial evaluated a berberine phospholipid formulation as an insulin sensitizer, reporting improvements in metabolic and hormonal markers.
Human studyMechanistic trial on CVD risk factors
A randomized controlled trial examined berberine's effect on cardiovascular disease risk factors, exploring the mechanisms behind the changes observed.
Human RCTSystematic review of CVD risk markers
A systematic review pooled results from randomized trials on berberine supplementation and cardiovascular disease risk factors in adults.
Systematic reviewFrom preclinical evidence to the clinic
A review traced berberine's metabolic and cardiovascular research from early preclinical evidence through clinical study findings.
ReviewThe PREMOTE gut-microbiome trial
A large randomized, double-blind, placebo-controlled trial across 20 centres in China studied gut-microbiome-related effects of berberine, with and without probiotics, in adults with type 2 diabetes.
Human RCTA hidden therapeutic link
A review describes how berberine's interaction with the gut microbiota may underlie several of its studied metabolic effects.
ReviewEffects on the gastrointestinal microbiota
A review summarizes research on how berberine, which is poorly absorbed and remains largely in the gut, interacts with gastrointestinal microbiota.
ReviewThe AMPK-SREBP-1c-SCD1 pathway
Preclinical research traced berberine's effect on liver lipid metabolism to activation of the AMPK-SREBP-1c-SCD1 signaling pathway.
Preclinical (mouse)AMPK activation and cellular stress
A laboratory study found berberine enhanced AMPK activation and autophagy, reducing markers of high-glucose-induced cell stress.
Lab studyMapping berberine's molecular targets
A 2025 review mapped the multiple molecular targets and signaling pathways - including AMPK/mTOR - through which berberine's effects are studied.
ReviewTolerability of lipid-lowering nutraceuticals
A review of commonly used dietary supplements and nutraceuticals with lipid-lowering effects, including berberine, discussed their tolerability and safety profile.
ReviewA 30-day human safety study
A randomized crossover human study assessed the safety and tolerability of a berberine formulation over 30 days of daily use.
Human RCTDose-ranging safety in prediabetes
A randomized controlled trial evaluated the efficacy and safety of berberine on glycemic control in adults with prediabetes.
Human RCTBerberine across metabolic syndrome
A review examined berberine's studied relationship to the risk factors, course, and consequences of metabolic syndrome.
ReviewMeta-analysis across MetS components
A systematic review and meta-analysis comprehensively evaluated berberine's efficacy and safety across the individual components of metabolic syndrome.
Systematic review & meta-analysisBrown adipose tissue research
Translational research identified brown adipose tissue activation as one pathway through which berberine's metabolic effects have been studied.
ReviewFrequently asked questions
What is berberine and what does it do?
Berberine is a plant compound. AOR Berberine is a Natural Health Product that helps support healthy lipid levels (total cholesterol, LDL and triglycerides) and cardiovascular health.
How do I take it?
Adults (18 years and older) take 1 capsule (500 mg) 2 times a day with food, or as directed by a qualified health care practitioner. Consult a health care practitioner before using for more than 3 months.
What's the difference between the 60-capsule and 120-capsule bottles?
Both are the same 500 mg berberine formula at the standard 2-capsules-per-day dose. The 60-capsule bottle is a 30-day supply and the 120-capsule bottle is a 60-day supply, so you can choose based on how long you'd like your supply to last.
What's in it besides berberine?
Each capsule contains 500 mg of berberine with a small number of non-medicinal ingredients used in the capsule and manufacturing process - see the label for the full list. The capsule shell itself is vegan (hypromellose), with no gelatin.
Is it made in Canada?
Yes. It is manufactured in Canada by Advanced Orthomolecular Research (AOR) and licensed by Health Canada under NPN 80123625.
Who should not use it?
Consult a health care practitioner before use if you have a kidney disorder, diabetes, cardiovascular disease, liver or kidney disease, gall stones, a blood disorder or leucopenia, hypoglycemia, or hypotension, or if you are taking prescription medication, pregnant, breastfeeding, or planning to become pregnant.
Can I take it alongside my cholesterol or diabetes medication?
Consult your health care practitioner before use if you are taking prescription medication, as berberine may alter the effectiveness of these medications. This product is not intended to replace any prescription medication.
Where do I buy it?
Use the orange button on this page - it takes you to the AOR listing on Amazon.ca for secure checkout and fast delivery.
Support healthy cholesterol & cardiovascular health the easy way
Get AOR Berberine on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80123625. Berberine helps support healthy lipid levels and cardiovascular health. The research summaries below concern the compound berberine and are educational - they are not claims about this finished product, and are not intended to suggest berberine as a substitute for any prescription medication. Read and follow the label. Consult a health care practitioner prior to use if you have a kidney disorder, diabetes, cardiovascular disease, liver or kidney disease, gall stones, a blood disorder, hypoglycemia, hypotension, or are taking prescription medication, or if you are pregnant, breastfeeding, or plan to become pregnant. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a health care practitioner prior to use if you have a kidney disorder, have diabetes, cardiovascular disease, liver or kidney disease, gall stones, a blood disorder or leucopenia, hypoglycemia, hypotension, or if you are taking prescription medication as this may alter the effectiveness of these medications. If you experience sweating, paleness, chills, headache, dizziness and/or confusion, discontinue use and consult a health care practitioner. Do not use if you are pregnant, breastfeeding, or plan to become pregnant. May cause additional gastrointestinal upsets such as constipation, vomiting and abdominal pain/cramps, in which case discontinue use and consult a health care practitioner. Some people may experience skin irritation, facial flushing and slowed heart rate.
Indications
Recommended Use or Purpose: Helps support healthy lipid levels (i.e. total cholesterol, LDL cholesterol and triglycerides). Helps to maintain and support cardiovascular health.
Ingredients
Medicinal Ingredient (per capsule): Berberine 500 mg (as 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium). Non-medicinal ingredients: Carrot Root Powder, Hypromellose, Maltodextrin, Microcrystalline Cellulose, Silicon Dioxide, Sodium Stearyl Fumarate. NMIs are subject to change - always read and follow the label.
Directions
Recommended Dose (Adults 18 years and older): Take 1 capsule 2 times a day with food, or as directed by a health care practitioner. Do not exceed the recommended dose unless instructed by a health care practitioner. Consult a health care practitioner for use beyond 3 months. Do not open capsules, as this may compromise the stability of the medicinal ingredients.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.