AOR Benfotiamine Vitamin B1 80mg - Energy Support | 120 Caps
Visit the AOR Store| Brand | AOR |
| Serving | 1 capsule (80 mg benfotiamine) |
| Licensed Natural Health Product | NPN 80007920 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- HIGH-BIOAVAILABILITY VITAMIN B1: Benfotiamine is a fat-soluble form of vitamin B1 with a superior ability to penetrate cell membranes compared with conventional thiamin - 80 mg in one easy-to-swallow capsule.
- SUPPORTS NERVE HEALTH & COMFORT: Helps maintain the normal function of the nervous system and healthy nerve function, supporting everyday nerve comfort as part of a wellness routine.
- SUPPORTS ENERGY PRODUCTION & CIRCULATION: Helps in energy production and supports healthy circulation; some people use it for occasional support with lower-leg swelling.
- SUPPORTS MENTAL CLARITY & CONCENTRATION: As part of the vitamin B complex, benfotiamine supports the nervous-system function tied to everyday mental clarity and concentration.
- PART OF A HEALTHY BLOOD SUGAR ROUTINE: Helps maintain the body's ability to metabolize nutrients, including carbohydrates, as part of a broader routine for healthy blood sugar regulation.
- SMALL, EASY-TO-SWALLOW CAPSULES: 120 vegan capsules per bottle - up to a 120-day supply of small, easy-to-swallow capsules.
- VEGAN, NON-GMO, GLUTEN-FREE: Free from wheat, gluten, corn, nuts, dairy, soy and animal by-products - vegan and non-GMO.
- TRUSTED CANADIAN MANUFACTURING: Made in Canada by Advanced Orthomolecular Research (AOR), GMP-compliant and licensed under Health Canada NPN 80007920.
Product Description
Benfotiamine - A High-Bioavailability Form of Vitamin B1
A highly bioavailable, fat-soluble form of vitamin B1. Benfotiamine's superior ability to penetrate cell membranes increases its bioavailability over conventional thiamin supplements, supporting energy production, healthy nerve function and the body's ability to metabolize nutrients - in one small, easy-to-swallow capsule. Licensed Natural Health Product NPN 80007920.
Une forme de vitamine B1 hautement biodisponible et liposoluble. La capacité supérieure du benfotiamine à pénétrer les membranes cellulaires augmente sa biodisponibilité par rapport aux suppléments de thiamine conventionnels, soutenant la production d'énergie, une fonction nerveuse saine et la capacité du corps à métaboliser les nutriments - en une seule petite capsule facile à avaler. Produit de santé naturel homologué. NPN 80007920.
AOR Benfotiamine 80 mg
High-bioavailability vitamin B1 - Vegan, Non-GMO, Gluten-Free
Backed by science
Benfotiamine has been studied for its higher bioavailability versus conventional thiamin and its role in energy metabolism, nerve function and glucose-metabolism research.
The AOR difference
80 mg of benfotiamine per capsule - vegan, non-GMO, gluten-free and made in Canada with no animal by-products.
What AOR Benfotiamine Supports
A high-bioavailability form of vitamin B1 - four ways it supports everyday health.
Energy Production
Helps in energy production and supports the body's overall energy metabolism.
Healthy Nerve Function
Helps maintain the normal function of the nervous system and healthy nerve function.
Nutrient Metabolism
Helps maintain the body's ability to metabolize nutrients, including carbohydrates.
Cellular Protection
Contributes to the maintenance of healthy cells as part of overall wellness.
AOR Benfotiamine: Supplement Facts
Per Capsule:
- B1 Thiamin (Benfotiamine)80 mg
Non-Medicinal Ingredients: Microcrystalline cellulose, sodium stearyl fumarate. Capsule: hypromellose. Vegan, non-GMO and gluten-free. NMIs are subject to change - always read and follow the label.
Recommended Use or Purpose: Helps in energy production. Helps maintain the normal function of the nervous system and healthy nerve function. Helps maintain the body's ability to metabolize nutrients. Source of thiamine (vitamin B1) provided as benfotiamine, a highly bioavailable form of thiamin with a superior ability to penetrate cell membranes compared with conventional thiamin supplements.
Recommended Dose (Adults 18 years and older): Take 1 capsule daily with food, or as directed by a qualified health care practitioner. Do not crush, blend or mix the capsules; swallow whole. Do not exceed the recommended dose unless directed by a health care practitioner.
Cautions and Warnings: Do not use if you are pregnant or breastfeeding. Persons with thiamin hypersensitivity should not take this product. Consult a health care practitioner if symptoms persist or worsen. Do not use if the safety seal under the cap is broken or missing. Keep out of reach of children. Store in a cool, dry place, tightly sealed. For adults 18 years and older.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Par capsule :
- Thiamine B1 (Benfotiamine)80 mg
Ingrédients non médicinaux : Cellulose microcristalline, stéarylfumarate de sodium. Capsule : hypromellose. Végétalien, sans OGM et sans gluten. Les ingrédients non médicinaux peuvent changer - toujours lire et suivre l'étiquette.
Usage ou fins recommandés : Aide à la production d'énergie. Aide à maintenir la fonction normale du système nerveux et une fonction nerveuse saine. Aide à maintenir la capacité du corps à métaboliser les nutriments. Source de thiamine (vitamine B1) fournie sous forme de benfotiamine, une forme de thiamine hautement biodisponible ayant une capacité supérieure à pénétrer les membranes cellulaires comparativement aux suppléments de thiamine conventionnels.
Dose recommandée (adultes de 18 ans et plus) : Prendre 1 capsule par jour avec de la nourriture, ou selon les directives d'un praticien de soins de santé qualifié. Ne pas écraser, broyer ou mélanger les capsules; avaler les capsules entières. Ne pas dépasser la dose recommandée sauf indication contraire d'un praticien de soins de santé.
Mises en garde et précautions : Ne pas utiliser si vous êtes enceinte ou si vous allaitez. Les personnes ayant une hypersensibilité à la thiamine ne devraient pas prendre ce produit. Consulter un praticien de soins de santé si les symptômes persistent ou s'aggravent. Ne pas utiliser si le sceau de sécurité sous le bouchon est brisé ou manquant. Garder hors de la portée des enfants. Conserver dans un endroit frais et sec, bien fermé. Pour les adultes de 18 ans et plus.
NPN 80007920
Support energy production, metabolism & healthy nerve function daily
Get AOR Benfotiamine on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy AOR Benfotiamine
A high-bioavailability form of vitamin B1 - trusted Canadian quality.
Higher bioavailability
Benfotiamine's superior ability to penetrate cell membranes increases its bioavailability over conventional thiamin.
Energy & nerve support
Helps in energy production and helps maintain healthy nerve function.
Small, easy-to-swallow capsules
120 vegan capsules per bottle - up to a 120-day supply.
Premium Canadian brand
AOR - Advanced Orthomolecular Research, since 1991. NPN 80007920.
How to use
Take daily
Take 1 capsule daily with food, or as directed by a qualified health care practitioner.
Swallow whole
Do not crush, blend or mix the capsules - swallow whole with water.
Stay consistent
Use daily for consistent support; do not exceed the recommended dose unless instructed by a health care practitioner.
Long-lasting supply
120 capsules per bottle - up to a 120-day (4-month) supply at one capsule per day.
What the research says about benfotiamine (vitamin B1)
Educational summaries of published research on thiamine and its higher-bioavailability form, benfotiamine - shared for education, not as claims about this finished product. AOR Benfotiamine's claims are the statements authorized under its Natural Health Product licence, NPN 80007920.
Improved neuropathy symptom score (BENDIP trial)
In a phase III placebo-controlled trial in 165 patients with diabetic polyneuropathy, 6 weeks of benfotiamine (300 or 600 mg/day) significantly improved the Neuropathy Symptom Score in the per-protocol population, with the largest improvement for pain and at the higher dose; treatment was well tolerated in all groups.
Human RCTA rigorous 12-month trial found no change in nerve-fibre measures
A randomized, placebo-controlled trial (the BOND study) followed 57 people with type 2 diabetes and symptomatic polyneuropathy for 12 months; benfotiamine reliably raised blood thiamine levels and was well tolerated, but produced no significant change versus placebo in corneal nerve-fibre length or other morphometric, neurophysiological and clinical measures - only the Neuropathy Symptom Score showed a non-significant improving trend.
Human RCTReduced nerve collagen changes in an animal model
In hyperglycemic rats, daily oral benfotiamine reduced collagen IV content in the sciatic nerve compared with untreated hyperglycemic controls, part of preclinical work on structural changes in peripheral nerves under high-glucose conditions.
Animal studyA role in converting carbohydrates to energy
Thiamine plays a crucial role in energy metabolism, helping convert carbohydrates into usable energy and supporting the nervous system, heart and muscles; reviews describe benfotiamine as a higher-bioavailability precursor developed to help compensate for thiamine deficiency.
ReviewA decades-long link between thiamine and diabetes
The first reports connecting thiamine and diabetes date to the 1940s; a role for thiamine deficiency in diabetic neuropathy became evident soon after, and benfotiamine has been studied for diabetic complications since the late 1990s, building on earlier findings on thiamine's effects on microvascular cells.
ReviewA candidate natural metabolic-receptor ligand
Molecular docking and cell studies found that thiamine forms a stable interaction with PPAR-gamma, a nutrient-sensing receptor central to glucose and fat metabolism, and induced adipocyte responses in lab models - part of ongoing research into nutrient-based approaches to metabolic health.
MechanismA systematic review of glycemic outcomes
A systematic review and meta-analysis of 6 randomized trials (364 participants) found that thiamine or benfotiamine (100-900 mg/day, up to 3 months) did not significantly improve HbA1c or blood-glucose measures in type 2 diabetes, though benfotiamine reduced triglycerides at a lower dose and thiamine supplementation raised HDL cholesterol.
Systematic reviewVitamins and derivatives in metabolic syndrome
A review of vitamins and their derivatives in metabolic syndrome and type 2 diabetes highlights benfotiamine, a thiamine derivative, as having anti-AGE (advanced glycation end-product) properties relevant to diabetes-associated complications.
ReviewNo significant change in glycation or inflammation markers over 12 weeks
In a randomized trial in people with type 2 diabetes and early kidney changes, 12 weeks of benfotiamine did not produce statistically significant reductions in plasma or urinary advanced glycation end-products, endothelial-dysfunction markers or inflammation markers compared with placebo.
Human RCTBuilt for higher bioavailability
Reviews describe benfotiamine as a synthetic thiamine precursor with higher bioavailability and tissue penetration than thiamine itself, developed because ordinary water-soluble thiamine is absorbed and used inefficiently at higher intakes.
ReviewRaised tissue thiamine levels in an animal model
In endurance-trained mice, oral benfotiamine raised thiamine levels in blood and muscle and altered some energy-metabolism markers in trained muscle, though it did not change thiamine-dependent enzyme gene expression or improve endurance performance in this model.
Animal studyDose and pharmacokinetics in healthy adults
Phase I trials in healthy volunteers assessed single and multiple ascending oral doses of benfotiamine (150-1200 mg), characterizing how it is absorbed and cleared - the kind of pharmacokinetic data that underpins its use as a higher-bioavailability thiamine source.
Human trialCountering smoking-related vessel changes
In a randomized crossover study, cigarette smoking sharply reduced flow-mediated dilation (a measure of blood-vessel function) and raised a marker of vascular inflammation in healthy volunteers; a short course of benfotiamine significantly blunted both effects.
Human RCTProtecting cells in the retinal microcirculation
Laboratory co-culture models of retinal pericytes and endothelial cells - the two main cell types of the smallest retinal blood vessels - found that thiamine and benfotiamine reversed high-glucose-induced cell damage and restored normal cell interactions.
Lab studyReduced tissue damage in a dialysis model
In a rat model of peritoneal dialysis, benfotiamine treatment decreased peritoneal fibrosis, inflammation markers and abnormal blood-vessel growth, improving the characteristics of peritoneal transport.
Animal studyA modern, safety-monitored trial design
A randomized, placebo-controlled, 72-week trial protocol in 406 participants with early Alzheimer's disease was designed as a two-phase study - the first phase determines the highest safe, well-tolerated benfotiamine dose before it is carried into the larger efficacy phase, with real-time safety monitoring built in.
Trial protocolFavoured for its safety and efficacy profile
Reviews of thiamine's lipid-soluble derivatives describe benfotiamine as the leading choice among synthetic lipophilic thiamine compounds, citing its established safety and clinical-efficacy data compared with plain thiamine, which is limited by slower absorption and lower bioavailability.
ReviewA 12-month tolerability evaluation
A double-blind, randomized, placebo-controlled pilot study followed patients with diabetic sensorimotor polyneuropathy on benfotiamine over 12 months as part of the continued long-term clinical evaluation of its tolerability.
Human RCTA placebo-controlled trial in mild cognitive impairment
A 12-month, randomized, placebo-controlled phase IIa trial gave benfotiamine to individuals with amnestic mild cognitive impairment or mild dementia due to Alzheimer's disease; benfotiamine was safe and was associated with significantly less worsening on the clinical dementia rating scale versus placebo, an effect that was stronger in APOE-e4 non-carriers.
Human RCTPharmacological thiamine levels as a research strategy
A review discusses using higher, pharmacological levels of thiamine - above ordinary nutritional intake - as a therapeutic strategy being explored for Alzheimer's disease, building on preclinical evidence linking thiamine-dependent enzyme activity to the condition.
ReviewBlood vitamin B1 and cognitive scores
A retrospective study of 77 patients with Alzheimer's disease found that lower blood vitamin B1 levels were significantly associated with lower Mini-Mental State Examination scores, with a dose-dependent pattern linking more severe B1 deficiency to lower cognitive scores.
Observational studyChickens, polished rice and a paralysis clue
In the 1880s-1890s Dutch East Indies, Christiaan Eijkman observed that chickens fed polished white rice developed a leg paralysis resembling beriberi, while those fed unpolished brown rice did not; Gerrit Grijns, who succeeded him, correctly concluded that food contained an unknown substance needed for the peripheral nervous system - work that eventually led to thiamin's isolation.
HistoricalFrom beriberi to a Nobel Prize
Eijkman's work in Batavia searching for the cause of beriberi - originally suspected to be an infection - instead uncovered the animal model and dietary clues that led, through later researchers' fractionation work, to the identification of thiamine as the active nutrient; his findings were recognized with a Nobel Prize.
HistoricalOne hundred years of vitamin science
A historical review traces how the discovery of vitamins as essential dietary factors - including thiamine (vitamin B1) - explained centuries-old diseases like beriberi, scurvy, rickets and pellagra, and made possible the industrial manufacturing processes behind modern vitamin supplementation.
HistoricalFrequently asked questions
What is benfotiamine and how is it different from regular thiamin?
Benfotiamine is a fat-soluble form of vitamin B1 (thiamin). Its superior ability to penetrate cell membranes increases its bioavailability over conventional water-soluble thiamin supplements.
How do I take it?
Adults (18 years and older) take 1 capsule daily with food, or as directed by a qualified health care practitioner. Do not exceed the recommended dose unless instructed.
What does benfotiamine do?
Benfotiamine helps in energy production, helps maintain the normal function of the nervous system and healthy nerve function, and helps maintain the body's ability to metabolize nutrients.
How long does one bottle last?
120 capsules per bottle - up to a 120-day (4-month) supply at one capsule per day.
Is it vegan and allergen-friendly?
Yes - vegan, non-GMO and gluten-free, with no wheat, dairy, soy, nuts or animal by-products.
Is it made in Canada?
Yes. It is manufactured in Canada in a GMP-compliant facility by AOR and licensed by Health Canada under NPN 80007920.
Who should not use it?
Do not use if you are pregnant or breastfeeding. Persons with thiamin hypersensitivity should not take this product. Consult a health care practitioner if symptoms persist or worsen.
Where do I buy it?
Use the orange button on this page - it takes you to the AOR listing on Amazon.ca for secure checkout and fast delivery.
Support energy production, metabolism & healthy nerve function daily
Get AOR Benfotiamine on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80007920. Benfotiamine (vitamin B1) helps in energy production and helps maintain healthy nerve function and the body's ability to metabolize nutrients. The research summaries below concern thiamine and benfotiamine generally and are educational - they are not claims about this finished product. Read and follow the label. Consult a health-care practitioner before use if you are pregnant, breastfeeding, or taking other medications or supplements. Results may vary.
Important information
Safety Information
Cautions and Warnings: Do not use if you are pregnant or breastfeeding. Persons with thiamin hypersensitivity should not take this product. Consult a health care practitioner if symptoms persist or worsen. Do not use if the safety seal under the cap is broken or missing. Keep out of reach of children. Store in a cool, dry place, tightly sealed. For adults 18 years and older.
Indications
Recommended Use or Purpose: Helps in energy production. Helps maintain the normal function of the nervous system and healthy nerve function. Helps maintain the body's ability to metabolize nutrients. Source of thiamine (vitamin B1) provided as benfotiamine, a highly bioavailable form of thiamin with a superior ability to penetrate cell membranes compared with conventional thiamin supplements.
Ingredients
Medicinal Ingredient (per 1 capsule): B1 Thiamin (Benfotiamine) 80 mg. Non-medicinal ingredients: Microcrystalline cellulose, sodium stearyl fumarate. Capsule: hypromellose. Produced through pharmaceutical synthesis. NMIs are subject to change - always read and follow the label.
Directions
Recommended Dose (Adults 18 years and older): Take 1 capsule daily with food, or as directed by a qualified health care practitioner. Do not crush, blend or mix the capsules; swallow whole. Do not exceed the recommended dose unless directed by a health care practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.