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Health Canada NPN 80040811 33% andrographolides, standardized extract Vegan · Non-GMO · Gluten-free Made in Canada · GMP facility
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AOR Andrographis 300mg - Cold & Immune Support | 120 Caps

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$33.07 CAD
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BrandAOR
Serving1 capsule (300 mg extract)
Licensed Natural Health ProductNPN 80040811
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • STANDARDIZED HERBAL EXTRACT: Each capsule delivers 300 mg of Andrographis paniculata extract standardized to 33% andrographolides, the compound this traditional herb is measured by.
  • SEASONAL WELLNESS SUPPORT: Designed to support your body's natural defenses during seasonal transitions, helping adults maintain balance through the cold-and-flu season.
  • THROAT COMFORT: Andrographis is a traditional herb recognized for throat support, offering relief and ease when seasonal discomfort strikes.
  • TRADITIONAL COLD RELIEF: Used traditionally as an herbal remedy, and licensed by Health Canada, to help reduce the symptoms of the common cold and upper respiratory tract infections.
  • EASY-TO-SWALLOW CAPSULES: Available in convenient vegan capsules that fit easily into a daily routine for anyone who prefers herbal supplements over tinctures or teas.
  • CLEAN, DEPENDABLE FORMULA: AOR is dedicated to pure, dependable supplements - Andrographis is free of unnecessary fillers, non-GMO and gluten-free.
  • UP TO A 2-MONTH SUPPLY: 120 vegan capsules per bottle - 1 capsule twice daily lasts up to two months of consistent seasonal support.
  • PREMIUM CANADIAN QUALITY: Made in Canada in a GMP-compliant facility by Advanced Orthomolecular Research (AOR), licensed under Health Canada NPN 80040811.

Product description

Andrographis - Traditional Herbal Support for Immune Defense & Throat Comfort

AOR Andrographis

A standardized, high-potency Andrographis paniculata extract (33% andrographolides) in convenient vegan capsules. Andrographis is a traditional herbal remedy recognized for supporting immune defenses and seasonal wellness, with a long history of use for throat comfort and cold relief. Licensed Natural Health Product NPN 80040811.

Un extrait d'Andrographis paniculata standardisé et de haute puissance (33 % d'andrographolides) en capsules végétaliennes pratiques. L'andrographis est un remède à base de plantes traditionnel reconnu pour soutenir les défenses immunitaires et le bien-être saisonnier, avec un long historique d'utilisation pour le confort de la gorge et le soulagement du rhume. Produit de santé naturel homologué. NPN 80040811.

Andrographis lifestyle
AOR Andrographis
Premium - AOR

Standardized Andrographis Extract

300 mg per capsule, standardized to 33% andrographolides - Vegan, Non-GMO, Gluten-Free

Backed by tradition and science

Andrographis paniculata has a long history as a traditional herbal remedy for seasonal wellness, now studied for its andrographolide content and immune-supportive properties.

The AOR difference

300 mg of standardized 33% andrographolide extract per capsule - vegan, made in Canada, free of harmful additives.

What AOR Andrographis Supports

Andrographis paniculata is a traditional herbal remedy standardized for its andrographolide content - here is what it is used for.

Immune Defense

Helps support the body's natural immune defenses, especially through seasonal transitions.

Throat Comfort

A traditional herbal remedy recognized for easing throat discomfort when seasonal symptoms strike.

Cold Symptom Relief

Traditionally used, and licensed by Health Canada, to help reduce the symptoms of the common cold and upper respiratory tract infections.

Standardized Potency

Every capsule is standardized to 33% andrographolides for consistent, dependable potency from bottle to bottle.

AOR Andrographis: Supplement Facts

AOR™Andrographis
English

One Capsule contains:

  • Andrographis paniculata extract (33% andrographolides)300 mg

Non-Medicinal Ingredients: Microcrystalline cellulose and sodium benzoate. Capsule: hypromellose.

Recommended Use or Purpose: Helps reduce the symptoms of common cold and upper respiratory tract infections. Andrographis paniculata is a traditional herbal remedy recognized for supporting immune defenses and throat comfort during seasonal transitions.

Recommended Dose (Adults 18 years and older): Take 1 capsule 2 times per day, with or without food, or as directed by a qualified health-care practitioner. Do not crush, mix or blend capsules; swallow whole. Do not exceed the recommended dose unless directed by a health-care practitioner.

Cautions and Warnings: Do not use if you are pregnant or breastfeeding, or if you are allergic to plants of the Acanthaceae family. Consult a health-care practitioner prior to use if you are taking immunosuppressants, anticoagulants, antiplatelets or hypotensive medications (or supplements). Consult a health-care practitioner if symptoms persist or worsen. Some people may experience gastric discomfort, vomiting and/or loss of appetite. Animal research suggests andrographis may affect fertility; consult a health-care practitioner before use if you are trying to conceive. Keep out of reach of children. Store in a cool, dry place.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

Français

Une capsule contient :

  • Extrait d'Andrographis paniculata (33 % d'andrographolides)300 mg

Ingrédients non médicinaux : Cellulose microcristalline et benzoate de sodium. Capsule : hypromellose.

Usage ou fins recommandés : Aide à réduire les symptômes du rhume et des infections des voies respiratoires supérieures. L'andrographis paniculata est un remède à base de plantes traditionnel reconnu pour soutenir les défenses immunitaires et le confort de la gorge pendant les changements de saison.

Dose recommandée (adultes de 18 ans et plus) : Prendre 1 capsule 2 fois par jour, avec ou sans nourriture, ou selon les recommandations d'un professionnel de la santé qualifié. Ne pas écraser, mélanger ou broyer les capsules; avaler entières. Ne pas dépasser la dose recommandée sauf indication contraire d'un professionnel de la santé.

Mises en garde et précautions : Ne pas utiliser si vous êtes enceinte ou si vous allaitez, ou si vous êtes allergique aux plantes de la famille des Acanthacées. Consultez un professionnel de la santé avant l'utilisation si vous prenez des immunosuppresseurs, des anticoagulants, des antiplaquettaires ou des médicaments hypotenseurs (ou suppléments). Consultez un professionnel de la santé si les symptômes persistent ou s'aggravent. Certaines personnes peuvent ressentir des malaises gastriques, des vomissements et/ou une perte d'appétit. Des recherches chez l'animal suggèrent que l'andrographis pourrait affecter la fertilité; consultez un professionnel de la santé avant l'utilisation si vous essayez de concevoir. Garder hors de la portée des enfants. Conserver dans un endroit frais et sec.

NPN 80040811

33% andrographolides, standardized300 mg per capsule · 120 capsulesVegan · Non-GMO · Gluten-freeMade in Canada

Support your seasonal wellness routine

Get AOR Andrographis on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why AOR Andrographis

A standardized, single-herb extract - traditional support with modern quality control.

Standardized Potency

300 mg per capsule standardized to 33% andrographolides, so every dose delivers consistent, dependable potency.

Immune & Seasonal Support

Helps support the body's natural immune defenses through seasonal transitions.

Throat & Cold Relief

A traditional herbal remedy for throat comfort and reducing common cold symptoms.

Premium Canadian brand

AOR - Advanced Orthomolecular Research, since 1991. NPN 80040811.

Andrographis vs. the alternatives

Why a standardized, single-herb extract matters for seasonal wellness.

 AOR AndrographisGeneric andrographisMulti-herb cold blends
Andrographolide contentStandardized 33%Often unstandardizedDiluted or unclear
Dose per capsule300 mg extractVariesOften under-dosed
FormulaSingle herb, no fillersVariesMultiple actives, harder to dose
SourcingMade in Canada Made in CanadaVariesUnclear
Quality standardGMP · NPN-licensedVariesOften uncertified

How to use

Take 1 capsule

Adults (18 years and older) take one capsule of standardized Andrographis extract.

Twice daily

Take 1 capsule two times per day, with or without food.

Swallow whole

Do not crush, mix or blend capsules - swallow whole with water.

Stay consistent

Use daily through the season; one 120-capsule bottle lasts up to two months.

What the research says about Andrographis

Peer-reviewed studies and reviews on Andrographis paniculata and andrographolide - shared for education, not as claims about this finished product. AOR Andrographis's claim is the statement authorized under its Natural Health Product licence, NPN 80040811.

Common Cold & Upper Respiratory

Kan Jang eased uncomplicated URI symptoms

Randomized, placebo-controlled pilot and phase III trials found a standardized Andrographis paniculata fixed combination (Kan Jang) reduced the severity of cold-type symptoms in adults with uncomplicated upper-respiratory tract infection.

Human RCT
Melchior et al., Phytomedicine (2000)
Common Cold & Upper Respiratory

Placebo-controlled trial in URTI and sinusitis

A double-blind, placebo-controlled study found an Andrographis paniculata extract fixed combination eased symptoms of acute upper-respiratory tract infection, including sinusitis, versus placebo.

Human RCT
Gabrielian et al., Phytomedicine (2002)
Common Cold & Upper Respiratory

Modern phase III trial in the common cold

A phase III, double-blind, placebo-controlled trial of a standardized Andrographis paniculata extract (AP-Bio/KalmCold) reported efficacy and safety in adults with uncomplicated common cold.

Human RCT
Raj et al., Complementary Therapies in Medicine (2023)
Immune Modulation

Interferes with T-cell activation in animal models

Laboratory research describes andrographolide interfering with T-cell activation and antibody responses in mice, a proposed mechanistic basis for its immune-modulating reputation.

Mechanism
Iruretagoyena et al., J. Pharmacol. Exp. Ther. (2004)
Immune Modulation

Modulates cytokine signalling pathways

Cell-based research found andrographolide reduced IL-2 production in T-cells by interfering with NFAT and MAPK signalling pathways involved in immune-cell activation.

Mechanism
Carretta et al., Eur. J. Pharmacol. (2008)
Immune Modulation

Computational modelling of an inflammatory pathway

A molecular-docking and bioinformatics study modelled andrographolide binding to TNF- and NF-kB-pathway proteins implicated in inflammatory cytokine signalling.

Computational study
Rehan et al., Frontiers in Immunology (2021)
Throat & Symptom Relief

Classic pharyngotonsillitis trial

A randomized, double-blind study in adults with pharyngotonsillitis found high-dose Andrographis paniculata comparable to a common fever and sore-throat reliever in easing symptoms by day 3.

Human RCT
Thamlikitkul et al., J. Med. Assoc. Thai. (1991)
Throat & Symptom Relief

Symptom scores tracked with a visual analogue scale

A randomized, double-blind, placebo-controlled study used visual analogue scale ratings to measure how a standardized Andrographis paniculata extract (SHA-10) affected common-cold symptom prevalence and intensity.

Human RCT
Caceres et al., Phytomedicine (1999)
Throat & Symptom Relief

A throat spray formulation, tested directly

A randomized controlled trial found an Andrographis paniculata spray eased acute pharyngitis (sore throat) symptoms in adults.

Human RCT
Okonogi et al., Drug Discov. Ther. (2023)
Andrographolide Pharmacology

Mapping how the body processes andrographolide

A pharmacology review summarized the disposition kinetics (absorption, distribution, metabolism) and dosing considerations for oral Andrographis paniculata extracts.

Review
Songvut et al., Frontiers in Pharmacology (2022)
Andrographolide Pharmacology

Improving absorption with delivery-system research

An in vivo pharmacokinetic and toxicity evaluation studied a self-microemulsifying delivery system designed to improve the oral bioavailability of Andrographis paniculata extract.

Animal study
Pornpitchanarong et al., Eur. J. Pharm. Biopharm. (2026)
Andrographolide Pharmacology

Human pharmacokinetic data in clinical patients

A clinical pharmacokinetic-pharmacodynamic study characterized dosing and safety of standardized Andrographis paniculata capsules in adult patients.

Human study
Songvut et al., Frontiers in Pharmacology (2026)
Anti-Inflammatory Activity

Targets a key inflammatory signalling axis

Laboratory research found andrographolide acted on the Ptges3-Hsp90-NF-kB signalling axis, a pathway involved in chronic inflammatory processes.

Mechanism
Zhang et al., Journal of Advanced Research (2026)
Anti-Inflammatory Activity

Acts through the PI3K-Akt pathway

Animal research linked andrographolide to reduced inflammatory signalling via activation of the PI3K-Akt pathway.

Mechanism
Li et al., Int. Immunopharmacology (2026)
Anti-Inflammatory Activity

Blocks two inflammatory signalling cascades

In an animal model, andrographolide's anti-inflammatory action was linked to inhibition of the TLR4/NF-kB and TGF-beta1/Smad2 signalling pathways.

Mechanism
Lin et al., Oxid. Med. Cell. Longev. (2018)
Safety & Tolerability

A comprehensive look at safety data

A review compiled the pharmacological effects and safety profile of Andrographis paniculata reported across the research literature.

Review
Tian et al., Journal of Food Science (2022)
Safety & Tolerability

Reproductive safety studied in animal research

A study in male rats examined andrographis's effects on reproductive parameters, part of the evidence behind the conservative caution for those trying to conceive.

Animal study
Ogundola et al., Tissue & Cell (2021)
Safety & Tolerability

Tolerated in a controlled human trial

A randomized controlled trial of Andrographis paniculata extract in adults with hypertriglyceridemia reported on its safety and tolerability over the study period, alongside effects on triglyceride levels.

Human RCT
Phunikhom et al., J. Med. Assoc. Thai. (2015)
Comparative Herbal Research

Head-to-head against an antiviral medication

A randomized study compared Kan Jang (an Andrographis paniculata fixed combination) with amantadine, an antiviral medication, in the treatment of influenza.

Human RCT
Kulichenko et al., J. Herb. Pharmacother. (2003)
Comparative Herbal Research

Compared against two well-known adaptogenic herbs

A phase I clinical study compared Kan Jang against ginseng and valerian, two widely used medicinal herbs, assessing safety parameters in healthy male subjects.

Human study
Mkrtchyan et al., Phytomedicine (2005)
Comparative Herbal Research

Placebo-controlled in a modern respiratory illness

A randomized, quadruple-blind, placebo-controlled trial assessed Kan Jang in patients with mild COVID-19, a modern test of the same traditional respiratory-support combination.

Human RCT
Ratiani et al., Pharmaceuticals (Basel) (2023)
Traditional Use & Background

A comprehensive look at the 'King of Bitters'

A comprehensive review traced the ethnobotany, traditional uses, and pharmacological research on Andrographis paniculata (Kalmegh), long known in South and Southeast Asia as the 'King of Bitters'.

Review
Mehta et al., Comb. Chem. High Throughput Screen. (2022)
Traditional Use & Background

From traditional herb to modern chemistry

A review of andrographolide and its derivatives traced the compound's traditional background and summarized modern research into its properties.

Review
Ren et al., Molecules (2025)
Traditional Use & Background

Reviewing the compound's therapeutic potential

A review examined the therapeutic potential of andrographolide and its derivatives, a diterpenoid long used in traditional medicine across Asia.

Review
Shan et al., Pharmacol. Res. Perspect. (2025)

Frequently asked questions

What is Andrographis and what does it do?

Andrographis paniculata is a traditional herbal remedy standardized to 33% andrographolides. It is licensed by Health Canada to help reduce the symptoms of the common cold and upper respiratory tract infections.

How do I take it?

Adults (18 years and older) take 1 capsule two times per day, with or without food, or as directed by a qualified health-care practitioner. Do not crush, mix or blend capsules - swallow whole and do not exceed the daily dose.

How long does one bottle last?

Each bottle contains 120 vegan capsules - at 1 capsule twice daily, that is up to a 2-month supply.

Is it vegan and allergen-friendly?

Yes - the capsules are vegan, non-GMO and gluten-free. Andrographis is a member of the Acanthaceae plant family, so anyone with a known allergy to plants in that family should not use it.

Who should not use it?

Do not use if you are pregnant or breastfeeding. Consult a health-care practitioner before use if you are taking immunosuppressants, anticoagulants, antiplatelets or hypotensive medications (or supplements), or if you are trying to conceive.

Are there any side effects?

Some people may experience gastric discomfort, vomiting and/or loss of appetite. Consult a health-care practitioner if symptoms persist or worsen.

Is it made in Canada?

Yes. It is manufactured in Canada in a GMP-compliant facility by Advanced Orthomolecular Research (AOR) and licensed by Health Canada under NPN 80040811.

Where do I buy it?

Use the orange button on this page - it takes you to the AOR listing on Amazon.ca for secure checkout and fast delivery.

33% andrographolides, standardized300 mg per capsule · 120 capsulesVegan · Non-GMO · Gluten-freeMade in Canada

Support your seasonal wellness routine

Get AOR Andrographis on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80040811. Helps reduce the symptoms of common cold and upper respiratory tract infections. The research summaries below concern Andrographis paniculata and andrographolide generally and are educational - they are not claims about this finished product. Read and follow the label. Do not use if pregnant or breastfeeding. Consult a health care practitioner prior to use if you are taking immunosuppressants, anticoagulants, antiplatelets or hypotensive medications (or supplements), or if symptoms persist or worsen. Results may vary.

Important information

Safety Information

Cautions and Warnings: Do not use if you are pregnant or breastfeeding, or if you are allergic to plants of the Acanthaceae family. Consult a health-care practitioner prior to use if you are taking immunosuppressants, anticoagulants, antiplatelets or hypotensive medications (or supplements). Consult a health-care practitioner if symptoms persist or worsen. Some people may experience gastric discomfort, vomiting and/or loss of appetite. Animal research suggests andrographis may affect fertility; consult a health-care practitioner before use if you are trying to conceive. Keep out of reach of children. Store in a cool, dry place.

Indications

Recommended Use or Purpose: Helps reduce the symptoms of common cold and upper respiratory tract infections. Andrographis paniculata is a traditional herbal remedy recognized for supporting immune defenses and throat comfort during seasonal transitions.

Ingredients

Medicinal Ingredients: Serving Size: 1 Capsule. Andrographis paniculata extract (33% andrographolides) 300 mg. Non-medicinal ingredients: microcrystalline cellulose and sodium benzoate. Capsule: hypromellose. Non-medicinal ingredients are subject to change - always read and follow the label.

Directions

Recommended Dose (Adults 18 years and older): Take 1 capsule 2 times per day, with or without food, or as directed by a qualified health-care practitioner. Do not crush, mix or blend capsules; swallow whole. Do not exceed the recommended dose unless directed by a health-care practitioner.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.