AOR Ortho Eyes - N-Acetyl-Carnosine Eye Drops for Glare & Cataracts | 2x5ml
Visit the AOR Store| Brand | AOR |
| Serving | 2 drops per eye (2 x 5 mL vials) |
| Licensed Natural Health Product | NPN 80024426 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- HELPS REDUCE GLARE: Licensed Natural Health Product claim: helps reduce glare - AOR Ortho Eyes is formulated with 1.0% N-Acetyl-Carnosine to support comfortable, clear-feeling vision in bright or glaring light.
- IMPROVES AGE-RELATED EFFECTS SUCH AS CATARACTS: Licensed claim: improves age-related effects such as cataracts. N-Acetyl-Carnosine acts as a topical antioxidant that supports the eye against oxidative stress as it ages.
- SIMPLE TWICE-DAILY APPLICATION: Adults apply 2 drops in each eye, twice per day - 2 sterile 5 mL vials give up to a 25-day supply.
- STERILE, SINGLE-ACTIVE FORMULA: A sterile, ophthalmic-grade isotonic solution (pH 6.3 to 6.4) with one active ingredient - N-Acetyl-Carnosine 1.0% - and no unnecessary additives beyond what the eye's surface needs.
- VEGETARIAN FORMULA: A vegetarian ophthalmic solution, free of animal-derived ingredients.
- A DIFFERENT INGREDIENT FROM AOR'S ORAL N-A-C: A topical eye drop delivering N-Acetyl-Carnosine (an eye-specific antioxidant dipeptide) - not the same active ingredient as AOR's oral N-A-C capsule (N-Acetyl-Cysteine), which is a separate, unrelated product.
- PREMIUM CANADIAN QUALITY: Made in Canada by Advanced Orthomolecular Research (AOR), licensed under Health Canada NPN 80024426.
- BACKED BY DECADES OF OPHTHALMIC RESEARCH: N-Acetyl-Carnosine eye drops have been studied in peer-reviewed ophthalmology literature since the 1990s, including review in the Cochrane Database of Systematic Reviews.
Product Description
Ortho Eyes - N-Acetyl-Carnosine Eye Drops
AOR Ortho Eyes delivers 1.0% N-Acetyl-Carnosine in a sterile, ophthalmic-grade eye drop to help reduce glare and improve age-related effects such as cataracts. Two sterile 5 mL vials, applied 2 drops per eye twice daily. Licensed Natural Health Product, NPN 80024426. Licensed Natural Health Product NPN 80024426.
AOR Ortho Eyes offre 1,0 % de N-Acétyl-Carnosine dans une solution ophtalmique stérile pour aider à réduire l'éblouissement et améliorer les effets liés à l'âge tels que les cataractes. Deux fioles stériles de 5 ml, à raison de 2 gouttes par oeil, deux fois par jour. Produit de santé naturel homologué, NPN 80024426.
1.0% N-Acetyl-Carnosine, Sterile Eye Drops
Single-ingredient ophthalmic antioxidant - Vegetarian, Made in Canada
Sterile, Ophthalmic-Grade Solution
Formulated at pH 6.3 to 6.4 to match the eye's natural environment, with sterile water, glycerin and a preservative system designed specifically for ocular use.
Two Vials, Up to a 25-Day Supply
2 x 5 mL sterile vials deliver 2 drops per eye, twice daily - simple to fit into a daily routine.
What N-Acetyl-Carnosine Supports
Research on N-Acetyl-Carnosine eye drops spans cataract, oxidative-stress and visual-comfort studies. Here is what this ophthalmic antioxidant is understood to do.
Reduced Glare Sensitivity
This product's licensed claim: helps reduce glare - studied for improving comfort in bright light and at night.
Age-Related Eye Support
Licensed claim: improves age-related effects such as cataracts, by supporting the lens against oxidative stress.
Antioxidant Protection
N-Acetyl-Carnosine acts on the eye's surface and anterior chamber as a topical antioxidant against everyday oxidative stress.
Visual Clarity & Comfort
Formulated to support clear, comfortable vision day after day, alongside the eye's natural moisture.
AOR Ortho Eyes: Supplement Facts
Each application (2 drops per eye) contains:
- N-Acetyl-Carnosine (NAC) ophthalmic solution1.0%
Non-Medicinal Ingredients: Sterile water (ophthalmic grade isotonic solution pH 6.3 to 6.4), glycerin (lubricant), citric acid, boric acid, hypromellose, potassium bicarbonate, benzyl alcohol (preservative).
Recommended Use or Purpose: Helps reduce glare and improves age-related effects such as cataracts. Licensed Natural Health Product, NPN 80024426.
Recommended Dose (Adults 18 years and older): Instill 2 drops in each eye, twice per day, or as directed by a qualified health care practitioner. Not recommended for children under the age of 12. Do not heat beyond room temperature; store unopened vials in the original box, away from light and sunlight, at room temperature.
Cautions and Warnings: For adults 18 years and older; not recommended for children under the age of 12. Application may cause temporary irritation of the eye. If the eye tissue becomes more inflamed, red, irritated or uncomfortable after using this product, or if the condition worsens or persists for more than 72 hours, discontinue use of the product and consult a physician. To avoid contamination, do not let the dropper tip touch the eye, eyelid, fingers or any other surface; replace the cap immediately after use. Open only one vial at a time and do not share vials with anyone else. Once opened, discard the vial and its contents after 30 days. Do not use if the seal is broken or if the solution changes colour or becomes cloudy. Keep this and all drugs out of the reach of children.
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. Manufactured by Advanced Orthomolecular Research (AOR), Calgary, Alberta. This item is sold and shipped by Amazon.ca.
Chaque application (2 gouttes par oeil) contient :
- N-acétyle-carnosine (NA) solution ophtalmique1.0%
Ingrédients non médicinaux : Eau stérile (solution isotonique de qualité ophtalmique, pH 6.3 à 6.4), glycérine (lubrifiant), acide citrique, acide borique, hypromellose, bicarbonate de potassium, alcool benzylique (agent de conservation).
Usage ou fins recommandés : Contribue à réduire l'éblouissement et à améliorer les effets liés à l'âge tels que les cataractes. Produit de santé naturel homologué, NPN 80024426.
Dose recommandée (adultes de 18 ans et plus) : Appliquer 2 gouttes dans chaque oeil, deux fois par jour, ou selon les recommandations d'un professionnel de la santé qualifié. Ce produit n'est pas recommandé pour les enfants de moins de 12 ans. Ne pas chauffer au-delà de la température ambiante; conserver les fioles non ouvertes dans leur boîte d'origine, à l'abri de la lumière et du soleil, à température ambiante.
Mises en garde : Pour les adultes de 18 ans et plus; non recommandé pour les enfants de moins de 12 ans. Peut causer une irritation temporaire de l'oeil. Si l'inflammation, la rougeur, l'irritation ou l'inconfort du tissu oculaire s'intensifient après l'utilisation de ce produit, ou si l'état s'aggrave ou persiste au-delà de 72 heures, cessez l'utilisation du produit et consultez un médecin. Pour éviter toute contamination, évitez de toucher l'embout du compte-gouttes à l'oeil, à la paupière, aux doigts ou à toute autre surface; remettez le bouchon immédiatement après l'utilisation. N'ouvrez qu'une seule fiole à la fois et ne la partagez avec personne. Une fois ouverte, jetez la fiole et son contenu après 30 jours. N'utilisez pas ce produit si le sceau est brisé ou si la solution change de couleur ou devient trouble. Gardez ce produit et tout autre médicament hors de la portée des enfants.
NPN 80024426
Add AOR Ortho Eyes to your daily routine
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Get it on Amazon.caWhy AOR Ortho Eyes
A sterile, single-ingredient N-Acetyl-Carnosine eye drop - premium AOR quality.
Single, clearly dosed active ingredient
1.0% N-Acetyl-Carnosine in a sterile ophthalmic solution - no unnecessary additives.
Licensed glare & age-related claim
Helps reduce glare and improves age-related effects such as cataracts, under Health Canada NPN 80024426.
Simple twice-daily drops
2 drops per eye, twice daily - 2 sterile vials give up to a 25-day supply.
Premium Canadian brand
AOR - Advanced Orthomolecular Research, since 1991. Made in Canada.
How to use it
2 drops in each eye, twice daily
Adults (18 years and older) apply 2 drops in each eye, 2 times per day, or as directed by a qualified health care practitioner. Not recommended for children under 12.
One vial at a time
Open only one 5 mL sterile vial at a time; once opened, use within 30 days. Together the 2 vials give up to a 25-day supply at the labeled dose.
Watch for irritation
Application may cause temporary irritation of the eye. If the eye becomes more inflamed, red, irritated or uncomfortable, or the condition worsens or persists for more than 72 hours, discontinue use and consult a physician.
What the research says about N-Acetyl-Carnosine (NAC)
Educational summaries of published research on N-Acetyl-Carnosine (NAC), the eye-specific antioxidant dipeptide in AOR Ortho Eyes; these summaries are educational and concern the ingredient generally, not additional product-specific claims. AOR Ortho Eyes' own licensed claim (NPN 80024426) is: helps reduce glare and improves age-related effects such as cataracts. Much of the foundational clinical research on ophthalmic N-acetylcarnosine comes from one research group and patent holder (Innovative Vision Products / Dr. M. Babizhayev); independent reviews - including a Cochrane systematic review - are included alongside it for balance.
Improved acuity and glare sensitivity in a 24-month trial
In a randomized, placebo-controlled study of 49 patients (76 eyes) with senile cataract, 90% of eyes treated with 1% N-acetylcarnosine eye drops twice daily showed improved best-corrected visual acuity and 88.9% showed improved glare sensitivity at 6 months, with benefits sustained to 24 months and good tolerability.
Human RCTA Cochrane review calls for larger, more rigorous trials
A Cochrane systematic review of N-acetylcarnosine eye drops for age-related cataract found the two available clinical studies lacked sufficient reported methodological detail to draw firm conclusions, and called for larger randomized, double-masked, placebo-controlled trials with validated visual-acuity, contrast-sensitivity and glare outcomes.
Systematic reviewA modern review of non-surgical cataract candidates
A 2022 ophthalmology review of pharmacological approaches to cataract lists topical N-acetylcarnosine among the antioxidant candidates that have clinically shown decreased lens opacity, alongside ongoing research into improved delivery methods.
ReviewProposed for a range of oxidative-stress eye conditions, including dry eye
A pharmacology review of N-acetylcarnosine's ocular drug metabolism describes the lubricant eye-drop formulation as showing promise across ophthalmic disorders with an oxidative-stress component - including cataract, dry eye and vitreous floaters - based on its dose-related bioavailability in the aqueous humor.
ReviewA mucoadhesive formulation designed for sustained ocular contact
N-acetylcarnosine lubricant eye drops were formulated with a mucoadhesive cellulose-based compound and corneal absorption promoters, designed to prolong contact time on the eye's surface and support comfortable, sustained delivery.
Formulation researchSupports corneal comfort in extended contact-lens wear
Clinical data cited in this review associate N-acetylcarnosine with compensating corneal acidosis and with well-tolerated use in therapeutic bandage contact lenses for anterior-segment conditions and post-LASEK care, alongside improved visual acuity and glare sensitivity after 9 months of eye-drop use.
Clinical reviewTargeting reactive oxygen species in the aging eye
A mechanistic review describes how reactive oxygen species generated in the anterior eye segment contribute to cataract and glaucoma, and outlines N-acetylcarnosine (acting as a prodrug of L-carnosine) as part of a patented antioxidant approach designed to counter this oxidative damage.
Mechanism reviewOxidative-stress biomarkers in the aging anterior eye
This review documents biomarkers of oxidative stress and lipid peroxidation in the anterior eye segment linked to lens cataract, describing N-acetylcarnosine lubricant eye drops as part of a therapeutic strategy studied to help offset this oxidative burden.
Mechanism reviewMitochondria as a source of eye-aging oxidative stress
This review identifies metabolically active mitochondria in lens cells as a major source of reactive oxygen species implicated in age-related (maturity-onset) cataract, providing the biochemical rationale for antioxidant approaches such as N-acetylcarnosine.
Mechanism reviewTolerability tracked across a large patient cohort
In a randomized, double-blind, placebo-controlled crossover trial plus a cohort of over 50,250 patients, N-acetylcarnosine eye-drop therapy was reported to have good efficacy, safety and tolerability for age-related cataract and diabetic ocular complications.
Human RCT + cohortWell tolerated across multiple modes of eye application
In a rabbit-eye study, 1% N-acetylcarnosine showed dose-dependent conversion to L-carnosine in the aqueous humor and was well tolerated across several application techniques (drop instillation, subconjunctival injection, ultrasound-assisted phoresis), with no adverse findings reported.
Animal studyEfficacy and tolerability in a 50,500-patient dataset
A prospective, randomized, double-masked, placebo-controlled crossover trial, combined with a database of over 50,500 patients, reported significant efficacy, safety and good tolerability for N-acetylcarnosine eye-drop therapy in age-related cataract.
Human RCT + databaseHow N-acetylcarnosine compares to other eye-health antioxidants
A review examining antioxidant supplements across cataract, glaucoma, macular degeneration and other eye conditions found little supporting evidence for many nutritional antioxidants in cataract specifically, but noted that lubricant drops containing N-acetylcarnosine may be helpful in the initial stages of the disease.
Comparative reviewThe pharmaceutical challenge of getting antioxidants into the lens
A pharmaceutical sciences review of topical antioxidant strategies for age-related cataract - carnosine-based approaches among them - examines the lens's anatomical and physiological barriers, framing why effective topical delivery to the lens is a genuine formulation challenge.
ReviewOutperforming a classic antioxidant in lab comparisons
Molecular studies of imidazole-containing compounds found N-acetylcarnosine and related peptidomimetics deactivated lipid hydroperoxides and protected membrane phospholipids more effectively than the lipophilic antioxidant vitamin E in these experimental models.
Mechanism researchA century of carnosine physiology, including the eye
This comprehensive physiology review traces over a century of carnosine research, highlighting its pH-buffering, metal-chelating and antioxidant/anti-glycation biochemistry, and names ocular disease among the areas where promising preclinical and clinical results have been reported for carnosine-based compounds.
Comprehensive reviewThe radical-scavenging chemistry behind the antioxidant claim
Foundational biochemistry work found that L-carnosine and the related compound carcinine efficiently scavenge hydroxyl radicals and inhibit lipid peroxidation in both membrane and aqueous environments - the antioxidant chemistry N-acetylcarnosine eye drops later delivered to ocular tissue.
Mechanism researchHow the eye converts NAC into its active antioxidant
In a rabbit-eye pharmacokinetic study, N-acetylcarnosine (unlike plain L-carnosine, which barely penetrates the eye) crossed the cornea and underwent dose-dependent hydrolysis to release active L-carnosine into the aqueous humor - the prodrug mechanism behind the eye-drop formulation.
Animal studyThe prodrug-activation chemistry behind the 1% dose
Pharmacology research on N-acetylcarnosine's ocular bioactivation describes it as an auto-induction prodrug: the 1% ophthalmic formulation is progressively deacetylated as it crosses the cornea, sustaining antioxidant activity in the aqueous humor from a single instilled dose.
Mechanism researchEngineering how long the dose stays on the eye
Ocular drug-delivery research on N-acetylcarnosine prodrug formulations studied mucoadhesive, corneal-absorption-promoting eye-drop designs intended to improve how much of an instilled dose is retained and absorbed, reporting anti-cataract activity in both human and canine eyes.
Formulation researchVisual-function gains tracked over a defined course of use
In older adults and older adults with cataract using 1% N-acetylcarnosine lubricant eye drops, visual acuity and glare-sensitivity measurements improved significantly over the treatment course, while the control group showed no such change from baseline.
Human studyBetter glare scores for older drivers
In a randomized, double-blind, placebo-controlled study of 65 older adults with cataract and 72 older drivers without cataract, 4 months of N-acetylcarnosine eye drops significantly improved halometer-measured glare sensitivity and visual acuity versus placebo, with good tolerability and no reported adverse effects.
Human RCTReal-world use tracked across tens of thousands of patients
Alongside a 9-month clinical study, this paper analyzed repurchase records for N-acetylcarnosine eye drops among more than 50,000 patients, using ongoing self-directed reordering as a real-world signal of perceived benefit and tolerability for glare and quality-of-vision complaints.
Clinical study + real-world dataA preliminary look at canine cataracts
In a preliminary study of 30 dogs with varying degrees of cataract, topical N-acetyl carnosine (combined with other antioxidants) produced a measurable, though modest, reduction in lens opacity by image analysis - most consistent in early-stage (immature cataract or nuclear sclerosis) cases - and most owners reported some visual improvement.
Veterinary studyFrequently asked questions
What is AOR Ortho Eyes?
A sterile ophthalmic eye drop delivering 1.0% N-Acetyl-Carnosine (NAC), a licensed Natural Health Product (NPN 80024426) that helps reduce glare and improves age-related effects such as cataracts. Each box contains 2 sterile 5 mL vials.
How do I use it?
Adults (18 years and older) apply 2 drops in each eye, twice per day, or as directed by a qualified health care practitioner. Not recommended for children under 12.
Is N-Acetyl-Carnosine the same as AOR's oral N-A-C capsule?
No. This product's active ingredient is N-Acetyl-Carnosine, an eye-specific antioxidant dipeptide applied as a topical eye drop (NPN 80024426). AOR's oral N-A-C capsule is a different ingredient, N-Acetyl-Cysteine (NPN 80005832), taken by mouth for respiratory and general antioxidant support. Despite sharing the informal 'NAC' nickname, these are two distinct compounds with separate Health Canada licences, and are not interchangeable.
How long does one box last?
Two 5 mL sterile vials give up to a 25-day supply at the labeled dose of 2 drops per eye, twice daily. Open only one vial at a time, and use each vial within 30 days of opening.
What if my eye feels irritated after using it?
Application may cause temporary irritation. If the eye becomes more inflamed, red, irritated or uncomfortable, or the condition worsens or persists for more than 72 hours, discontinue use and consult a physician.
Is it suitable for children or contact lens wearers?
It is not recommended for children under the age of 12. The product label does not give specific contact-lens instructions; if you wear contact lenses or have another eye condition, check with your eye care professional before use.
Is it vegetarian?
Yes - AOR Ortho Eyes is a vegetarian, sterile ophthalmic solution.
Is it made in Canada?
Yes - AOR (Advanced Orthomolecular Research) manufactures Ortho Eyes in Calgary, Alberta, Canada.
Add AOR Ortho Eyes to your daily routine
Get AOR Ortho Eyes on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80024426. Helps reduce glare and improves age-related effects such as cataracts. Research summaries below concern the ophthalmic antioxidant N-Acetyl-Carnosine generally and are educational, not additional product-specific claims. Read and follow the label. For adults 18 years and older; not recommended for children under 12. Application may cause temporary eye irritation - discontinue use and consult a physician if the eye becomes more inflamed, red, irritated or uncomfortable, or if the condition worsens or persists beyond 72 hours. AOR is the manufacturer; sold by Canadian Health & Care on Amazon.ca. Results may vary.
Important information
Safety Information
Cautions and Warnings: For adults 18 years and older; not recommended for children under the age of 12. Application may cause temporary irritation of the eye. If the eye tissue becomes more inflamed, red, irritated or uncomfortable after using this product, or if the condition worsens or persists for more than 72 hours, discontinue use of the product and consult a physician. To avoid contamination, do not let the dropper tip touch the eye, eyelid, fingers or any other surface; replace the cap immediately after use. Open only one vial at a time and do not share vials with anyone else. Once opened, discard the vial and its contents after 30 days. Do not use if the seal is broken or if the solution changes colour or becomes cloudy. Keep this and all drugs out of the reach of children.
Indications
Recommended Use or Purpose: Helps reduce glare and improves age-related effects such as cataracts. Licensed Natural Health Product, NPN 80024426.
Ingredients
Medicinal Ingredients: Serving Size: 2 drops per eye. N-Acetyl-carnosine (NAC) 1.0%. Non-medical Ingredients: Sterile water (ophthalmic grade isotonic solution pH 6.3 to 6.4), glycerin (lubricant), citric acid, boric acid, hypromellose, potassium bicarbonate, benzyl alcohol (preservative).
Directions
Recommended Dose (Adults 18 years and older): Instill 2 drops in each eye, twice per day, or as directed by a qualified health care practitioner. Not recommended for children under the age of 12. Do not heat beyond room temperature; store unopened vials in the original box, away from light and sunlight, at room temperature.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. Manufactured by Advanced Orthomolecular Research (AOR), Calgary, Alberta. This item is sold and shipped by Amazon.ca.