AOR Menopause Relief - Saffron & Fenugreek for Menopause Support | 60 Caps
Visit the AOR Store| Brand | AOR |
| Serving | 2 capsules daily (1 after breakfast, 1 after dinner) |
| Licensed Natural Health Product | NPN 80119717 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- TWO REAL ACTIVES IN EVERY CAPSULE: Fenugreek seed extract (Trigonella foenum-graecum, 20:1 extract) and Affron, a standardized saffron (Crocus sativus) stigma extract (3:1 extract, 3.48% crocin) - 264 mg combined per capsule.
- HELPS RELIEVE PERI- AND POST-MENOPAUSAL DISCOMFORTS: Fenugreek seed extract is used in Herbal Medicine to help relieve hot flashes, night sweats, sleep disruption/insomnia, irritability, and joint and muscle discomfort.
- HELPS PROMOTE A HEALTHY ESTROGENIC BALANCE: Fenugreek seed extract is used in Herbal Medicine to help promote a healthy estrogenic balance through the menopause transition.
- AFFRON SAFFRON FOR MOOD AND STRESS: Affron is used in Herbal Medicine to help ease agitation and/or nervousness and to help reduce symptoms of perceived stress such as fatigue, listlessness and irritability.
- SIMPLE TWICE-DAILY DOSING: Take 1 capsule after breakfast and 1 capsule after dinner - 60 capsules is up to a 1-month supply.
- VEGAN, CLEAN FORMULA: Microcrystalline cellulose, sodium stearyl fumarate, potato-derived dextrin and silica in a hypromellose capsule - vegan, non-GMO and gluten-free.
- UP TO A 1-MONTH SUPPLY: 60 vegan capsules per bottle, taken 2 per day.
- TRUSTED CANADIAN QUALITY: Manufactured in Canada in a GMP-compliant facility by Advanced Orthomolecular Research (AOR), a licensed Natural Health Product, NPN 80119717.
Product Description
AOR Menopause Relief - Fenugreek & Affron Saffron for Peri- and Post-Menopausal Comfort
A closer look at AOR Menopause Relief - a standardized fenugreek seed extract combined with Affron, a clinically studied saffron (Crocus sativus) extract, to help relieve peri- and post-menopausal discomforts like hot flashes, night sweats and irritability, help promote a healthy estrogenic balance, and ease agitation and stress-related symptoms. Licensed Natural Health Product, NPN 80119717. Licensed Natural Health Product NPN 80119717.
Un regard plus approfondi sur AOR Menopause Relief - un extrait standardisé de graines de fenugrec combiné à l'Affron, un extrait de safran (Crocus sativus) étudié cliniquement, pour aider à soulager les malaises péri- et post-ménopausiques comme les bouffées de chaleur, les sueurs nocturnes et l'irritabilité, aider à favoriser un équilibre œstrogénique sain, et soulager l'agitation et les symptômes liés au stress. Produit de santé naturel homologué, NPN 80119717.
Why AOR Menopause Relief
A standardized fenugreek extract and Affron saffron extract, each studied at essentially the dose in this capsule - not a proprietary blend of undisclosed amounts.
Backed by Dose-Matched Research
Both actives in AOR Menopause Relief have been studied in peri-menopausal women at essentially this same dose - 250 mg fenugreek extract and 14 mg Affron, each twice daily - summarized in the research section below.
The AOR Difference
Two real medicinal ingredients at clinically studied doses in one vegan capsule - non-GMO, gluten-free and made in Canada.
Advanced Ingredients, Superior Results
Two real ingredients, each contributing a distinct role - here is what fenugreek and Affron saffron extract each bring to the formula.
Fenugreek Seed Extract (Trigonella foenum-graecum)
A standardized 20:1 fenugreek seed extract studied in perimenopausal women at this same 250 mg twice-daily dose, where it was associated with improvements in hot flashes, night sweats and mood, alongside shifts in estradiol, FSH and SHBG toward a more balanced hormonal profile.
250 mg per capsule (20:1 extract; DHE 5 g dry; NLT 10% protodioscin, NLT 3% trigonelline, NLT 30% total saponins)
Affron (Saffron / Crocus sativus Stigma Extract)
Affron, a standardized saffron stigma extract studied at this same 14 mg twice-daily dose in perimenopausal women, where it was associated with improvements in mood and psychological symptoms including anxiety and low mood, without a significant effect on hot flashes themselves.
14 mg per capsule (3:1 extract; DHE 42 mg dry; 3.48% crocin, 0.03% safranal)AOR Menopause Relief: Supplement Facts
Medicinal Ingredients (per capsule)
- Fenugreek Seed Extract (Trigonella foenum-graecum, 20:1 extract; DHE 5 g)250 mg
- Affron (Saffron Stigma Extract) (Crocus sativus, 3:1 extract; DHE 42 mg; 3.48% crocin)14 mg
Non-Medicinal Ingredients: Microcrystalline cellulose, sodium stearyl fumarate, dextrin (potato), silica. Capsule: hypromellose.
Recommended Use or Purpose: Fenugreek seed extract is used in Herbal Medicine to help relieve peri- and post-menopausal discomforts such as hot flashes, night sweats, sleep disruption/insomnia, irritability, and joint and muscle discomfort, and to help promote a healthy estrogenic balance. Affron®, its saffron (Crocus sativus) stigma extract, is used in Herbal Medicine to help ease agitation and/or nervousness and to help reduce symptoms of perceived stress such as fatigue, listlessness and irritability. Licensed Natural Health Product, NPN 80119717.
Recommended Dose (Adults 18 years and older): Take 1 capsule after breakfast and 1 capsule after dinner, or as directed by a qualified health care practitioner. Do not open capsules, as this may compromise the stability of the medicinal ingredients. Up to a 1-month supply (60 capsules).
Cautions and Warnings: Consult a health care practitioner before use if you are pregnant or breastfeeding. Consult a health care practitioner before use if you suffer from a psychological disorder such as frequent anxiety or depression. Consult a health care practitioner if you are taking anticoagulants or antidepressants. Consult a health care practitioner if you have a coagulation disorder. Consult a health care practitioner before use if you have diabetes or take blood-sugar-lowering medication - fenugreek and saffron may lower blood glucose and could add to the effect of these medications. If you have a known allergy to peanuts, chickpeas or other legumes, consult a health care practitioner before use - fenugreek is a legume and may cross-react in people sensitized to other legumes. If symptoms persist or worsen, consult a health care practitioner.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Ingrédients médicinaux (par capsule)
- Extrait de graines de fenugrec (Trigonella foenum-graecum, extrait 20:1; DHE 5 g)250 mg
- Affron (extrait de stigmates de safran) (Crocus sativus, extrait 3:1; DHE 42 mg; 3,48 % crocine)14 mg
Ingrédients non médicinaux : Cellulose microcristalline, fumarate de stéaryle sodique, dextrine (pomme de terre), silice. Capsule : hypromellose.
Usage ou fins recommandés : Menopause Relief contient de l'extrait de graines de fenugrec, dont les études montrent qu'il aide à soulager les malaises post-ménopausiques et péri-ménopausiques et à favoriser un équilibre œstrogénique sain. Il aide à soulager les symptômes de la ménopause tels que les bouffées de chaleur, les sueurs nocturnes, les interruptions du sommeil et l'insomnie, l'irritabilité et l'inconfort articulaire et musculaire, favorisant ainsi la qualité de vie. Menopause Relief contient également de l'Affron®, une marque déposée de safran, qui contribue à l'équilibre de l'humeur. Affron® aide à soulager l'agitation et/ou la nervosité et à réduire les symptômes du stress perçu, tels que la fatigue, la lassitude et l'irritabilité. Produit de santé naturel homologué, NPN 80119717.
Dose recommandée (adultes de 18 ans et plus) : Prendre une capsule après le petit déjeuner et une autre après le dîner, ou selon les directives d'un praticien de la santé. Ne pas ouvrir les capsules, car cela pourrait compromettre l'intégrité des ingrédients médicinaux. Jusqu'à une réserve d'un mois (60 capsules).
Mises en garde et précautions : Consultez un professionnel de la santé avant l'utilisation si vous êtes enceinte ou si vous allaitez. Consultez un praticien de soins de santé avant l'utilisation si vous souffrez d'un trouble psychologique tel que l'anxiété fréquente ou la dépression. Consultez un praticien de soins de santé si vous prenez des anticoagulants ou des antidépresseurs. Consultez un professionnel de la santé si vous souffrez d'un trouble de la coagulation. Consultez un professionnel de la santé avant l'utilisation si vous êtes diabétique ou si vous prenez des médicaments hypoglycémiants - le fenugrec et le safran peuvent abaisser la glycémie et amplifier l'effet de ces médicaments. Si vous avez une allergie connue aux arachides, aux pois chiches ou à d'autres légumineuses, consultez un professionnel de la santé avant l'utilisation - le fenugrec est une légumineuse et peut provoquer une réaction croisée chez les personnes sensibilisées aux légumineuses. Si les symptômes persistent ou s'aggravent, consultez un professionnel de la santé.
NPN 80119717
Support your menopause transition with fenugreek and Affron saffron
Get AOR Menopause Relief on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy AOR Menopause Relief
Fenugreek seed extract and Affron saffron extract, each with its own distinct, clinically studied role.
Peri- and Post-Menopausal Comfort
Fenugreek seed extract is used in Herbal Medicine to help relieve peri- and post-menopausal discomforts such as hot flashes, night sweats, sleep disruption and irritability.
Healthy Estrogenic Balance
Fenugreek seed extract is used in Herbal Medicine to help promote a healthy estrogenic balance through the menopause transition.
Affron Saffron for Mood & Stress
Affron, a standardized saffron extract, is used in Herbal Medicine to help ease agitation and nervousness and reduce symptoms of perceived stress like fatigue and irritability.
Premium Canadian Brand
AOR - Advanced Orthomolecular Research, since 1991. Vegan, non-GMO, gluten-free. NPN 80119717.
Inside every capsule
Each capsule provides 250 mg of a standardized fenugreek seed extract (20:1, DHE 5 g) alongside 14 mg of Affron, a standardized saffron (Crocus sativus) stigma extract (3:1, DHE 42 mg) - take one capsule after breakfast and one after dinner.
How to use
Take 1 capsule after breakfast
Adults 18 years and older: take 1 capsule after breakfast, or as directed by a qualified health care practitioner.
Take 1 capsule after dinner
Take a second capsule after dinner - 2 capsules daily provide 500 mg of fenugreek extract and 28 mg of Affron saffron extract.
Do not open capsules
Swallow capsules whole - opening them may compromise the stability of the medicinal ingredients.
Know when to check in
Consult a health care practitioner if symptoms persist or worsen, or before use if you have diabetes, a legume allergy, or take anticoagulants or antidepressants.
What the research says about fenugreek and Affron saffron
Peer-reviewed studies and reviews on the individual ingredients in Menopause Relief - shared for education, not as claims about this finished product. Menopause Relief's own claims are the statements authorized under its Natural Health Product licence, NPN 80119717.
RCT: Affron improved mood in perimenopausal women, at this product's own dose
A 12-week, randomized, double-blind, placebo-controlled trial of 14 mg Affron saffron extract twice daily in 86 perimenopausal women found significantly greater reductions in anxiety (33%) and depression (32%) scores on the Greene Climacteric Scale versus placebo, with no significant effect on hot flashes or other vasomotor symptoms.
Human RCTSystematic review: saffron eases several female reproductive system disorders
A systematic review of 50 studies on Crocus sativus and its compounds (crocin, crocetin, safranal, picrocrocin) found evidence that saffron can help ease symptoms of dysmenorrhea, premenstrual syndrome, menopause and polycystic ovary disease, alongside effects on sex-hormone regulation and ovarian protection.
Systematic reviewNutrition review names Affron among promising peri/postmenopause support
A literature review on bioactive compounds for peri- and postmenopausal women highlighted dietary supplementation with Affron saffron extract and Siberian rhubarb extract (ERr 731) as a versatile phytonutrient approach to correcting menopausal disorders through several distinct biological pathways.
ReviewRCT: fenugreek extract eased hot flashes and depression at this product's own dose
A 42-day, randomized, double-blind, placebo-controlled trial of a standardized fenugreek seed extract at 250 mg twice daily in perimenopausal women found significant reductions in hot flashes (25.9%), night sweats (26.5%), depression (31.8%) and insomnia (21.6%), alongside a shift in estradiol, FSH and SHBG toward a more balanced hormonal profile, without adverse safety findings.
Human RCTReview: fenugreek's menopause evidence is still developing
A review of herbal products for menopause and gynecological disorders found consistent clinical support for black cohosh and red clover, while noting that currently available data do not yet fully support fenugreek, hops, valerian or soy for menopausal symptom relief - a reminder that individual-ingredient research continues to evolve.
ReviewAnimal study: fenugreek supported memory pathways after ovariectomy
In ovariectomized rats, a model of surgical menopause, dietary fenugreek seed extract improved brain-derived neurotrophic factor (BDNF) levels and dendritic branching in the hippocampus - mechanistic findings that may help explain menopause-related memory concerns, not yet confirmed in human trials of this product.
Animal studyThe original Affron trial: improved mood in healthy adults
A 4-week, randomized, double-blind, placebo-controlled trial of Affron saffron extract (28 mg/day) in 128 healthy adults reporting low mood found a significant reduction in total mood disturbance and symptoms of stress and anxiety versus placebo, with no reported side effects.
Human RCTLargest Affron trial to date: fewer depressive symptoms over 12 weeks
The largest randomized, placebo-controlled trial of Affron conducted to date (202 adults, 12 weeks) found a significantly greater reduction in depression scores with saffron (28 mg/day) versus placebo, with 72% of the saffron group reaching a clinically meaningful improvement, and no serious adverse reactions reported.
Human RCTInternational clinical guidelines: saffron provisionally recommended for depression
A joint World Federation of Societies of Biological Psychiatry and Canadian Network for Mood and Anxiety Treatments guideline, reviewing Grade-A evidence across nutraceuticals and phytoceuticals, gave saffron a 'provisionally recommended' rating as an adjunctive option for unipolar depression, with acceptable safety and tolerability for over-the-counter use.
Clinical guidelineMeta-analysis: both saffron and fenugreek measurably lower blood glucose
A systematic review and meta-analysis of 19 studies found both fenugreek and saffron supplementation reduced fasting blood glucose and HbA1c, with fenugreek also lowering post-prandial glucose - educational findings about the ingredients, not a blood-sugar claim for this product.
Meta-analysisRCT: fenugreek improved glucose control in type 2 diabetes
A randomized, double-blinded, placebo-controlled trial in patients with type 2 diabetes mellitus found 5 g of fenugreek powder twice daily significantly improved fasting blood sugar, HbA1c and several other measures versus placebo over two months.
Human RCTWhy the diabetes-medication caution matters
A Canadian Journal of Diabetes clinical review of natural health products with hypoglycemic effects lists fenugreek among agents that can additively lower blood glucose when used alongside conventional diabetes medications, and recommends people with diabetes disclose natural health product use to their health care team.
Clinical reviewToxicology study: standardized fenugreek extract well tolerated at high doses
Acute, sub-chronic (90-day) and genotoxicity studies of a standardized, saponin-rich fenugreek seed extract in rats found no toxicologically significant changes in behavior, organ weight, blood chemistry or genetic material even at doses far above typical human intake, establishing a wide margin of safety.
Toxicology studyReview flags fenugreek's pregnancy and legume-allergy considerations
A toxicology review of fenugreek notes that its saponin content has been linked to anti-fertility and abortifacient activity in animal studies, so the review advises against use during pregnancy, and separately advises that people with peanut or chickpea allergies avoid fenugreek because of possible cross-reactivity.
ReviewCase report: real-world peanut-fenugreek cross-reactivity
A clinical case report documented an allergic cross-reaction between peanut and fenugreek, illustrating why people with a known peanut or other legume allergy are advised to consult a health care practitioner before using fenugreek-containing products.
Case reportComprehensive review maps the botanical landscape for menopause
A wide-ranging pharmacological review of botanicals for women's health surveys the estrogenic and serotonergic mechanisms proposed across black cohosh, red clover, soy, hops, chasteberry and other menopause-support botanicals, and cautions that even 'natural' options warrant awareness of potential interactions.
ReviewRCT: a different ginger-saffron-cinnamon blend also eased menopause symptoms
A randomized, placebo-controlled trial of a different herbal capsule combining ginger, saffron (Crocus) extract and cinnamon in postmenopausal women found a statistically significant improvement in Menopause Rating Scale scores versus placebo after four weeks - a useful point of comparison for saffron-containing menopause formulas generally.
Human RCTRCT: a fennel-chamomile-saffron blend improved menopause rating scores
A triple-blind, placebo-controlled trial of oral herbal drops combining fennel, chamomile and saffron in peri-menopausal women found significant improvements in physical, psychological and urogenital menopause-symptom domains at higher doses over 12 weeks.
Human RCTCrocin and safranal: saffron's two signature actives
A pharmacology review traces saffron's therapeutic properties to crocin and safranal, its two major bioactive constituents, which have shown antioxidant, anti-inflammatory and mood-related actions across preclinical and a smaller number of clinical studies.
ReviewSaffron's actives can cross the blood-brain barrier
A comprehensive review of saffron's nutritional and health properties describes how its apocarotenoid and monoterpenoid constituents, including safranal, crocin and picrocrocin, show high bioavailability and the ability to cross the blood-brain barrier, supporting its studied effects on mood, anxiety and cognition.
ReviewDiosgenin: a steroidal compound related to fenugreek's saponins
A pharmacological review of diosgenin - a steroidal sapogenin related to fenugreek's saponin content, including protodioscin - summarizes preclinical evidence across metabolic, cognitive and bone-health pathways, while noting further well-designed clinical trials are still needed.
ReviewCenturies of traditional fenugreek use across three medicine systems
A historical review traces fenugreek's use as a medicinal and culinary herb across Iranian, Indian and Chinese traditional medicine for centuries, traditionally valued for digestive, metabolic and women's reproductive health support long before modern extract standardization.
Historical reviewSaffron's ancient roots as spice, dye and medicine
A review of Crocus sativus describes saffron's very ancient history of use, valued since antiquity not only as a spice but also for its coloring and medicinal qualities, long before the modern isolation of crocin, crocetin, picrocrocin and safranal.
ReviewSaffron in Traditional Chinese Medicine
A phytochemistry review notes saffron entered Traditional Chinese Medicine by 1979, where it was traditionally used for sleeplessness, low mood and anxiety among other conditions - traditional uses that parallel some of the mood-related effects studied in modern clinical trials.
ReviewFrequently asked questions
What is AOR Menopause Relief and what does it do?
AOR Menopause Relief combines a standardized fenugreek seed extract with Affron, a standardized saffron (Crocus sativus) extract. Fenugreek is used in Herbal Medicine to help relieve peri- and post-menopausal discomforts such as hot flashes, night sweats, sleep disruption and irritability, and to help promote a healthy estrogenic balance. Affron is used in Herbal Medicine to help ease agitation, nervousness and symptoms of perceived stress.
How do I take it?
Adults 18 years and older: take 1 capsule after breakfast and 1 capsule after dinner, or as directed by a qualified health care practitioner.
What is Affron?
Affron is a standardized extract of saffron (Crocus sativus) stigmas, standardized to 3.48% crocin, providing 14 mg per capsule (3:1 extract, DHE 42 mg).
I have diabetes or take blood-sugar-lowering medication - is this safe for me?
Consult a health care practitioner before use. Both fenugreek and saffron can lower blood glucose, and combining them with diabetes medication may add to that effect.
I have a peanut or chickpea allergy - can I take this?
Fenugreek is a legume and has been documented to cross-react in some people with peanut, chickpea or other legume allergies. Consult a health care practitioner before use if this applies to you.
Does it contain common allergens?
The non-medicinal ingredients are microcrystalline cellulose, sodium stearyl fumarate, potato-derived dextrin and silica in a hypromellose capsule. It is vegan, non-GMO and gluten-free.
Who else should be cautious using this product?
Consult a health care practitioner before use if you are pregnant or breastfeeding, have a psychological disorder such as frequent anxiety or depression, have a coagulation disorder, or take anticoagulants or antidepressants.
Where do I buy it?
Use the orange button on this page - it takes you to the AOR listing on Amazon.ca for secure checkout and fast delivery.
Support your menopause transition with fenugreek and Affron saffron
Get AOR Menopause Relief on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80119717. Fenugreek seed extract is used in Herbal Medicine to help relieve peri- and post-menopausal discomforts such as hot flashes, night sweats, sleep disruption/insomnia, irritability, and joint and muscle discomfort, and to help promote a healthy estrogenic balance. Affron, its saffron (Crocus sativus) stigma extract, is used in Herbal Medicine to help ease agitation and/or nervousness and reduce symptoms of perceived stress such as fatigue, listlessness and irritability. The research summaries below concern fenugreek (Trigonella foenum-graecum) and saffron (Crocus sativus) individually and are educational - they are not claims about this finished product. Read and follow the label. Consult a health care practitioner before use if you are pregnant or breastfeeding, if you have diabetes or take blood-sugar-lowering medication, if you have a known allergy to peanuts, chickpeas or other legumes, if you have a psychological disorder such as frequent anxiety or depression, if you have a coagulation disorder, or if you are taking anticoagulants or antidepressants. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a health care practitioner before use if you are pregnant or breastfeeding. Consult a health care practitioner before use if you suffer from a psychological disorder such as frequent anxiety or depression. Consult a health care practitioner if you are taking anticoagulants or antidepressants. Consult a health care practitioner if you have a coagulation disorder. Consult a health care practitioner before use if you have diabetes or take blood-sugar-lowering medication - fenugreek and saffron may lower blood glucose and could add to the effect of these medications. If you have a known allergy to peanuts, chickpeas or other legumes, consult a health care practitioner before use - fenugreek is a legume and may cross-react in people sensitized to other legumes. If symptoms persist or worsen, consult a health care practitioner.
Indications
Recommended Use or Purpose: Fenugreek seed extract is used in Herbal Medicine to help relieve peri- and post-menopausal discomforts such as hot flashes, night sweats, sleep disruption/insomnia, irritability, and joint and muscle discomfort, and to help promote a healthy estrogenic balance. Affron®, its saffron (Crocus sativus) stigma extract, is used in Herbal Medicine to help ease agitation and/or nervousness and to help reduce symptoms of perceived stress such as fatigue, listlessness and irritability. Licensed Natural Health Product, NPN 80119717.
Ingredients
Medicinal Ingredients (per capsule): Fenugreek Seed Extract (Trigonella foenum-graecum, 20:1 extract; DHE 5 g dry; NLT 10% Protodioscin, NLT 3% Trigonelline, NLT 30% Total Saponins) 250 mg, Affron® (Crocus sativus stigma extract; 3:1 extract; DHE 42 mg dry; 3.48% Crocin, 0.03% safranal) 14 mg. Non-medicinal ingredients: Microcrystalline cellulose, sodium stearyl fumarate, dextrin (potato), silica. Capsule: hypromellose. NMIs are subject to change - always read and follow the label.
Directions
Recommended Dose (Adults 18 years and older): Take 1 capsule after breakfast and 1 capsule after dinner, or as directed by a qualified health care practitioner. Do not open capsules, as this may compromise the stability of the medicinal ingredients. Up to a 1-month supply (60 capsules).
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.