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Health Canada NPN 80032486 Single-Ingredient Chios Mastic Gum Vegan - Non-GMO - Gluten-Free Made in Canada - 120 Capsules
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AOR Mastica Chios 400mg - Pure Chios Mastic Gum for Digestive Comfort | 120 Caps

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$65.70 CAD
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BrandAOR
Serving1 capsule, 3 times daily
Licensed Natural Health ProductNPN 80032486
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • PURE CHIOS MASTIC GUM: Each vegan capsule delivers 400 mg of Chios mastic gum (Pistacia lentiscus var. Chia), a resin traditionally harvested exclusively on the Greek island of Chios - a single, standardized ingredient with no proprietary blends.
  • HELPS RELIEVE HEARTBURN & STOMACH DISCOMFORT: Helps alleviate stomach pain and heartburn associated with functional dyspepsia, for everyday digestive comfort.
  • A TRADITIONAL AYURVEDIC & MEDITERRANEAN REMEDY: Traditionally used in Herbal Medicine (Ayurveda) to help relieve occasional gas (Adhmana) in the stomach and intestines, and used for centuries in traditional Greek medicine for gastric comfort.
  • UP TO A 40-DAY SUPPLY: 120 vegan capsules per bottle at the recommended dose of 1 capsule three times daily on an empty stomach - up to 40 days of gastric support.
  • VEGAN, NON-GMO CAPSULE: A vegan hypromellose capsule (no gelatin). Non-medicinal ingredients: microcrystalline cellulose, sodium stearyl fumarate, silicon dioxide. Always check the physical label for the most current ingredient and allergen information.
  • FOR OCCASIONAL USE: Formulated for occasional use; consult a health care practitioner for use beyond two weeks, or if symptoms persist or worsen.
  • ANACARDIACEAE ALLERGY CAUTION: Chios mastic gum comes from a tree in the Anacardiaceae (cashew) family. Do not use if you are allergic to Anacardiaceae family plants such as pistachio, cashew or mango.
  • MADE IN CANADA, NPN 80032486: A licensed Natural Health Product manufactured by AOR (Advanced Orthomolecular Research) in a GMP-compliant Canadian facility.

Product description

Mastica Chios - Pure Chios Mastic Gum

AOR Mastica Chios

A closer look at AOR Mastica Chios - 400 mg of pure Chios mastic gum (Pistacia lentiscus var. Chia) in every vegan capsule, traditionally harvested on the Greek island of Chios to help relieve heartburn and support digestive comfort. Licensed Natural Health Product NPN 80032486.

Un aperçu d'AOR Mastica Chios - 400 mg de gomme de mastic de Chios pure (Pistacia lentiscus var. Chia) dans chaque capsule végétalienne, traditionnellement récoltée sur l'île grecque de Chios pour aider à soulager les brûlures d'estomac et soutenir le confort digestif.

Mastica Chios lifestyle
AOR Mastica Chios
Premium - AOR

Pure Chios Mastic Gum, One Ingredient

400 mg Pistacia lentiscus var. Chia resin per capsule - Vegan, Non-GMO, Gluten-Free

Helps Relieve Heartburn & Dyspepsia

Helps alleviate stomach pain and heartburn associated with functional dyspepsia, an ingredient backed by human clinical research on Chios mastic gum.

Single-Ingredient, Traditionally Harvested

Just Chios mastic gum - a resin traditionally harvested on the Greek island of Chios and used for centuries to support digestive comfort.

One Resin, Focused Digestive Support

Research on Chios mastic gum supports a role in gastric comfort, from stomach-lining support to the digestive system's response to occasional irritation.

Heartburn & Dyspepsia Relief

Helps alleviate stomach pain and heartburn associated with functional dyspepsia.

Gastric Lining Support

Studied for a traditional role in supporting the stomach's protective lining and easing occasional gastric discomfort.

Digestive Comfort

Traditionally used in Ayurveda to help relieve occasional gas (Adhmana) in the stomach and intestines.

Antioxidant Mechanisms

Research describes antioxidant and anti-inflammatory activity among Chios mastic gum's triterpene compounds.

Mediterranean Tradition

Used for more than 2,500 years in traditional Greek medicine for gastric comfort, referenced in the works of ancient physicians.

Single-Ingredient Purity

Just 400 mg of Chios mastic gum per vegan capsule - no fillers beyond the minimum non-medicinal ingredients.

AOR Mastica Chios: Supplement Facts

AOR™Mastica Chios
English

Each capsule contains:

  • Chios mastic gum Pistacia lentiscus var. Chia, resin400 mg

Non-Medicinal Ingredients: Non-medicinal ingredients: Microcrystalline cellulose, sodium stearyl fumarate, silicon dioxide. Capsule: hypromellose.

Recommended Use or Purpose: Helps alleviate stomach pain and heartburn associated with functional dyspepsia. Traditionally used in Herbal Medicine (Ayurveda) to help relieve occasional gas (Adhmana) in the stomach and intestines. Licensed under Health Canada NPN 80032486.

Recommended Dose (Adults 18 years and older): Take 1 capsule three times daily on an empty stomach, or as directed by a qualified health care practitioner. Do not exceed the recommended daily dose unless instructed by a health care practitioner. Recommended Duration of Use: For occasional use only; consult a health care practitioner for use beyond two weeks.

Cautions and Warnings: Do not use if you are pregnant or breastfeeding, or if you have an allergy to Anacardiaceae family plants (such as pistachio, cashew or mango). Consult a health care practitioner before use if symptoms persist or worsen, if you have diabetes mellitus or Crohn's disease, or if you are taking hypoglycemic or hypolipidemic (lipid-lowering) agents. Known Adverse Reactions: Discontinue use if hypersensitivity (such as an allergy) occurs.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. Manufactured by Advanced Orthomolecular Research (AOR), Calgary, Alberta. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

Français

Chaque capsule contient :

  • Gomme de mastic de Chios Pistacia lentiscus var. Chia, résine400 mg

Ingrédients non médicinaux : Ingrédients non médicinaux : Cellulose microcristalline, stéaryl fumarate de sodium, dioxyde de silicium. Capsule : hypromellose.

Usage ou fins recommandés : Aide à soulager les douleurs à l'estomac et les brûlures d'estomac associées à la dyspepsie fonctionnelle. Traditionnellement utilisé en médecine herboriste (Ayurveda) pour aider à soulager les gaz occasionnels (Adhmana) dans l'estomac et les intestins. Autorisé sous le NPN 80032486 de Santé Canada.

Dose recommandée (adultes de 18 ans et plus) : Prendre 1 capsule trois fois par jour à jeun (estomac vide), ou selon les recommandations d'un professionnel de la santé qualifié. Ne pas dépasser la dose quotidienne recommandée sauf indication contraire d'un professionnel de la santé. Durée d'utilisation recommandée : Pour une utilisation occasionnelle seulement; consultez un professionnel de la santé pour un usage au-delà de deux semaines.

Mises en garde et précautions : Ne pas utiliser si vous êtes enceinte ou allaitez, ou si vous êtes allergique aux plantes de la famille des Anacardiacées (comme la pistache, la noix de cajou ou la mangue). Consultez un professionnel de la santé avant l'utilisation si les symptômes persistent ou s'aggravent, si vous souffrez de diabète sucré ou de la maladie de Crohn, ou si vous prenez des agents hypoglycémiants ou hypolipémiants. Réactions indésirables connues : Cessez l'utilisation en cas d'hypersensibilité (par exemple, une allergie).

NPN 80032486

Pure Chios Mastic Gum (Pistacia lentiscus)Helps relieve heartburn & stomach discomfortVegan Capsules - Non-GMO - Gluten-FreeMade in Canada - 120 Capsules, 40-Day Supply

Give your stomach the comfort it deserves

Get AOR Mastica Chios on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why AOR Mastica Chios

Pure, single-ingredient Chios mastic gum - premium AOR quality for heartburn and digestive comfort.

Health Canada-Recognized Relief

Helps alleviate stomach pain and heartburn associated with functional dyspepsia.

Traditionally Harvested on Chios

Pistacia lentiscus var. Chia resin, harvested exclusively on the Greek island of Chios, with more than 2,500 years of traditional use.

Single-Ingredient Purity

Just Chios mastic gum at 400 mg per capsule - no proprietary blends.

Vegan, Canadian Quality

Vegan hypromellose capsules, non-GMO and gluten-free - made in Canada in a GMP-compliant facility, NPN 80032486.

How to use

Take 1 capsule, 3 times daily

Adults 18 years and older take 1 capsule three times daily on an empty stomach, or as directed by a qualified health care practitioner.

Take on an empty stomach

For best results, take each capsule on an empty stomach, spaced through the day.

Occasional use

Formulated for occasional use. Consult a health care practitioner for use beyond two weeks.

Check with your practitioner first

Consult a health care practitioner before use if you have diabetes mellitus, Crohn's disease, take hypoglycemic or hypolipidemic agents, or are allergic to the Anacardiaceae (cashew) family.

What the research says about Mastica Chios's ingredient

Peer-reviewed studies and reviews on Chios mastic gum (Pistacia lentiscus var. Chia) - shared for education, not as claims about this finished product. Mastica Chios's claim is the statement authorized under its Natural Health Product licence, NPN 80032486.

Mastic Gum & H. Pylori / Gastritis Research

A pilot trial found no eradication from mastic gum alone

In a randomized pilot study, standard triple antibiotic therapy achieved significant Helicobacter pylori eradication (77%), while mastic gum alone showed only a non-significant trend toward eradication - suggesting a supportive rather than stand-alone antibacterial role.

Human RCT
Dabos et al., Phytomedicine (2009)
Mastic Gum & H. Pylori / Gastritis Research

Chios mastic gum extract reduced H. pylori colonization in mice

Three months of oral mastic extract cut Helicobacter pylori colonization roughly 30-fold in infected mice, though it did not reduce the associated chronic gastric inflammation in this model.

Animal study
Paraschos et al., Antimicrobial Agents and Chemotherapy (2006)
Mastic Gum & H. Pylori / Gastritis Research

Identifying mastic's anti-H. pylori compounds

Screening the essential oil of mastic gum identified alpha-terpineol and (E)-methyl isoeugenol as components active against four drug-resistant Helicobacter pylori strains isolated from gastritis, ulcer and gastric cancer patients.

Lab study
Miyamoto et al., Natural Products and Bioprospecting (2014)
Mastic Gum & Peptic Ulcer / Gastric-Lining Research

A 1984 double-blind trial of mastic for duodenal ulcer

In a double-blind, placebo-controlled trial, symptomatic relief occurred in 80% of patients taking mastic versus 50% on placebo, and endoscopically confirmed healing was seen in 70% on mastic versus 22% on placebo (p<0.01).

Human RCT
Al-Habbal, Al-Habbal & Huwez, Clinical and Experimental Pharmacology and Physiology (1984)
Mastic Gum & Peptic Ulcer / Gastric-Lining Research

Mastic protected the gastric lining across multiple ulcer models

In rats, oral mastic significantly reduced gastric mucosal damage induced by aspirin, phenylbutazone and cold-restraint stress, with a cytoprotective effect against ethanol that was reversed by prior indomethacin treatment - pointing to a prostaglandin-related mechanism.

Animal study
Al-Said et al., Journal of Ethnopharmacology (1986)
Mastic Gum & Peptic Ulcer / Gastric-Lining Research

Extending the case for mastic in benign gastric ulcer

A clinical study from the same research group behind the 1984 duodenal-ulcer trial examined mastic specifically in the treatment of benign gastric ulcers.

Clinical study
Huwez & Al-Habbal, Gastroenterologia Japonica (1986)
Mastic Gum & Digestive Comfort / Dyspepsia Research

A placebo-controlled trial eased functional dyspepsia

Among 148 patients with functional dyspepsia, three weeks of Chios mastic gum produced significantly lower symptom scores than placebo (14.78 vs 19.96), with marked improvement reported by 77% of the mastic group versus 40% on placebo.

Human RCT
Dabos et al., Journal of Ethnopharmacology (2009)
Mastic Gum & Digestive Comfort / Dyspepsia Research

Real-world follow-up in diabetic gastroparesis

A 24-week real-world follow-up study evaluated the safety and long-term effectiveness of Pistacia lentiscus (mastic gum) for diabetic gastroparesis, tracking the Gastrointestinal Cardinal Symptom Index against the standard prokinetic comparator levosulpiride.

Clinical study
Kant et al., Indian Journal of Pharmacology (2024)
Mastic Gum & Digestive Comfort / Dyspepsia Research

2,500 years of use, reviewed for inflammatory bowel disease

A review tracing Chios mastic gum's more than 2,500 years in traditional Greek medicine summarizes its chemical profile and pharmacological properties relevant to chronic digestive inflammation, from past use to future research directions.

Review
Ottria et al., International Journal of Molecular Sciences (2023)
Anti-Inflammatory & Antioxidant Mechanism

A key mastic compound eased colitis in mice

Masticadienonic acid, one of the most abundant compounds in Chios mastic gum, reduced disease activity in a mouse colitis model by modulating inflammatory markers, gut barrier integrity and the gut microbiota.

Animal study
Cui et al., Phytomedicine (2022)
Anti-Inflammatory & Antioxidant Mechanism

Boosting the body's own antioxidant enzymes

In a zebrafish model, Chios mastic gum extract upregulated three key antioxidant proteins - superoxide dismutase, thioredoxin reductase and catalase - alongside effects on cellular energy metabolism.

Lab study
Anastasiadou et al., International Journal of Molecular Sciences (2025)
Anti-Inflammatory & Antioxidant Mechanism

New mastic compounds outperformed a positive-control drug

Two newly isolated triterpenoids from mastic inhibited inflammatory nitric oxide production in immune cells more potently than the positive-control anti-inflammatory drug dexamethasone in the same assay.

Lab study
Xiang et al., Fitoterapia (2025)
Safety & Tolerability

No genotoxicity found at a high test dose

A rodent bone-marrow micronucleus study found no mortality, clinical toxicity signs, organ pathology or statistically significant genotoxic change after dosing Chios mastic gum at 2000 mg/kg body weight for three days.

Safety study
Psarou et al., Toxicology Reports (2025)
Safety & Tolerability

Same genus, real cross-sensitivity with pistachio

In children with confirmed pistachio sensitivity, skin testing found 96% also reacted to terebinth (Pistacia terebinthus) - the same genus as Chios mastic's Pistacia lentiscus - supporting caution for Anacardiaceae-allergic individuals around any Pistacia-derived ingredient.

Human study
Celik et al., International Archives of Allergy and Immunology (2024)
Safety & Tolerability

Cross-reactivity within the Anacardiaceae family, case-documented

A 2025 case report examined cross-reactivity patterns within the Anacardiaceae family in a pistachio-allergic patient, part of a growing clinical literature mapping which family members do and do not cross-react.

Case report
Marquart & Kinaciyan, Journal of Investigational Allergology and Clinical Immunology (2025)
Comparative Digestive-Herb Research

Mastic performed comparably to a standard ulcer drug

In rats exposed to cold-restraint stress, pretreatment with Chios mastic gum reduced gastric and colonic mucosal damage as significantly as omeprazole, a standard medication used to prevent and treat stress-related gastritis.

Animal study
Kakagia et al., Journal of Critical Care Medicine (2020)
Comparative Digestive-Herb Research

Added to standard therapy, with a symptom-score edge

Adding mastic gum to standard bismuth quadruple therapy for H. pylori produced a numerically higher eradication rate (85% vs 67%) and a significantly greater improvement in dyspepsia symptom scores than quadruple therapy alone, with high compliance in both arms.

Human RCT
Tulsian et al., Indian Journal of Gastroenterology (2026)
Comparative Digestive-Herb Research

Form matters: whole mastic outperformed processed forms

In the CHIOS-MASTIHA pilot trial, whole (total) Chios mastic gum significantly lowered cholesterol and fasting glucose versus placebo, while polymer-free and powdered mastic forms at similar doses did not reach significance - highlighting that preparation format affects outcomes.

Human RCT
Kartalis et al., European Journal of Preventive Cardiology (2015)
Foundational Pistacia Lentiscus Phytochemistry

Mapping mastic's terpene chemistry in detail

Advanced mass-spectrometry analysis characterized 70 terpene compounds in mastic (Pistacia lentiscus L.) extract, accurately identifying 20 of them against reference standards by their fragmentation patterns.

Phytochemistry
Kahaer et al., Phytochemical Analysis (2024)
Foundational Pistacia Lentiscus Phytochemistry

Measuring mastic's triterpenes in human plasma

Researchers developed and validated a mass-spectrometry method to quantify isomasticadienonic and masticadienonic acid - mastic's two principal triterpenes, comprising roughly 70% of its chemical makeup - directly in human plasma, noting mastic's recognition by the European Medicines Agency as an herbal medicinal product.

Phytochemistry
Brieudes et al., Planta Medica (2021)
Foundational Pistacia Lentiscus Phytochemistry

Nearly 70 constituents, five categories of activity

A review of Chios mastic gum's roughly 70 constituents groups its documented biomedical properties into five areas: antibacterial/antifungal, anti-inflammatory/immune, cardiovascular, anticancer and digestive-symptom improvement.

Review
Dimas et al., In Vivo (2012)
Traditional Greek & Mediterranean Use History

Referenced by Herodotus, Dioscorides and Galen

A review traces mastic's use in traditional Greek medicine for gastralgia and peptic ulcers back more than 2,500 years, with its healing properties referenced in the works of Herodotus, Dioscorides and Galen and by later Roman, Byzantine and Arab physicians.

Review
Paraschos, Mitakou & Skaltsounis, Current Medicinal Chemistry (2012)
Traditional Greek & Mediterranean Use History

Ancient texts to modern phytotherapy

A comprehensive review compiled ethnopharmacology sources - from the ancient writings of Galen, Theophrastus and Dioscorides to records held by the Chios Mastiha Growers Association - tracing Chios mastic gum's path from a Greek folk remedy to a studied phytotherapeutic.

Ethnopharmacology review
Pachi et al., Journal of Ethnopharmacology (2020)
Traditional Greek & Mediterranean Use History

The living tradition, documented in the field

A modern ethnobotanical survey of Greece's North Aegean islands - the island group that includes Chios - interviewed 200 local informants and catalogued 109 medicinal plants still used in the region's traditional herbal practice today.

Ethnobotanical survey
Axiotis et al., Frontiers in Pharmacology (2018)

Frequently asked questions

What is in AOR Mastica Chios?

Each capsule contains a single medicinal ingredient: 400 mg of Chios mastic gum (Pistacia lentiscus var. Chia), a resin traditionally harvested on the Greek island of Chios.

What does it help with?

It helps alleviate stomach pain and heartburn associated with functional dyspepsia, and is traditionally used in Herbal Medicine (Ayurveda) to help relieve occasional gas in the stomach and intestines.

How do I take it?

Adults 18 years and older take 1 capsule three times daily on an empty stomach, or as directed by a qualified health care practitioner. It's formulated for occasional use - consult a health care practitioner for use beyond two weeks.

Is it vegan?

Yes. The capsule shell is hypromellose (no gelatin), and the formula is vegan, non-GMO and gluten-free.

Does it contain any allergens?

Chios mastic gum comes from a tree in the Anacardiaceae (cashew) family. Do not use if you are allergic to Anacardiaceae family plants such as pistachio, cashew or mango. Discontinue use if hypersensitivity occurs.

Who should check with a doctor before using it?

Do not use if pregnant or breastfeeding. Consult a health care practitioner before use if you have diabetes mellitus or Crohn's disease, or take hypoglycemic or hypolipidemic (lipid-lowering) agents.

How long does one bottle last?

120 capsules is up to a 40-day supply at the recommended dose of 1 capsule three times daily.

Is Chios mastic gum the same as pistachio?

No - it's a resin from the mastic tree (Pistacia lentiscus var. Chia), a different species in the same Anacardiaceae plant family as pistachio and cashew. That shared family is why the label carries an Anacardiaceae allergy caution.

Pure Chios Mastic Gum (Pistacia lentiscus)Helps relieve heartburn & stomach discomfortVegan Capsules - Non-GMO - Gluten-FreeMade in Canada - 120 Capsules, 40-Day Supply

Give your stomach the comfort it deserves

Get AOR Mastica Chios on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80032486. Mastica Chios helps alleviate stomach pain and heartburn associated with functional dyspepsia. The research summaries below concern Chios mastic gum generally and are educational - they are not claims about this finished product beyond its licensed monograph. Read and follow the label. Consult a health care practitioner if symptoms persist or worsen, for use beyond two weeks, or if you have diabetes mellitus, Crohn's disease, or an allergy to the Anacardiaceae (cashew) family. Do not use if pregnant or breastfeeding. Results may vary.

Important information

Safety Information

Cautions and Warnings: Do not use if you are pregnant or breastfeeding, or if you have an allergy to Anacardiaceae family plants (such as pistachio, cashew or mango). Consult a health care practitioner before use if symptoms persist or worsen, if you have diabetes mellitus or Crohn's disease, or if you are taking hypoglycemic or hypolipidemic (lipid-lowering) agents. Known Adverse Reactions: Discontinue use if hypersensitivity (such as an allergy) occurs.

Indications

Recommended Use or Purpose: Helps alleviate stomach pain and heartburn associated with functional dyspepsia. Traditionally used in Herbal Medicine (Ayurveda) to help relieve occasional gas (Adhmana) in the stomach and intestines. Licensed under Health Canada NPN 80032486.

Ingredients

Medicinal Ingredients (Serving Size: 1 Capsule): Chios mastic gum (Pistacia lentiscus var. Chia) - 400 mg. Non-medicinal Ingredients: Microcrystalline cellulose, sodium stearyl fumarate, silicon dioxide. Capsule: hypromellose. NMIs are subject to change - always read and follow the label.

Directions

Recommended Dose (Adults 18 years and older): Take 1 capsule three times daily on an empty stomach, or as directed by a qualified health care practitioner. Do not exceed the recommended daily dose unless instructed by a health care practitioner. Recommended Duration of Use: For occasional use only; consult a health care practitioner for use beyond two weeks.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. Manufactured by Advanced Orthomolecular Research (AOR), Calgary, Alberta. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.