AOR Lysine Hyaluronic Acid with Vitamin C - Collagen & Connective Tissue Support | 60-120 Caps
Visit the AOR Store| Brand | AOR |
| Dose | 1 capsule, twice daily |
| Licensed Natural Health Product | NPN 80028874 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- THREE REAL ACTIVES, ONE VEGAN CAPSULE: Each capsule provides 98.5 mg hyaluronic acid, 75 mg lysine (as L-lysine monohydrochloride) and 50 mg vitamin C - real per-capsule doses straight from this product's own Health Canada-licensed label, not a proprietary blend.
- HELPS IN COLLAGEN & CONNECTIVE TISSUE FORMATION: Health Canada-licensed to help in collagen and connective tissue formation, and to help in the development and maintenance of bones and cartilage.
- SUPPORTS THE IMMUNE SYSTEM & WOUND HEALING: Vitamin C also helps maintain and support the immune system and helps in wound healing, alongside its role in collagen formation.
- VEGAN, NON-GMO & GLUTEN-FREE: A vegan capsule with a short, transparent non-medicinal ingredient list - no gelatin and no unnecessary fillers.
- SIMPLE DAILY DOSE: Adults take 1 capsule, twice daily, with or without food. Swallow capsules whole - do not crush, blend or mix.
- TWO SIZES, SAME FORMULA: Available as a 60-capsule 30-day supply or a 120-capsule 60-day supply - identical formula, identical NPN.
- CLEAN CANADIAN QUALITY YOU CAN TRUST: Made in Canada in a GMP-compliant facility. Licensed Natural Health Product, NPN 80028874 - read the label for full details.
Product description
AOR Lysine, Hyaluronic Acid with Vitamin C - Collagen, Connective Tissue & Skin Support
A vegan capsule combining three real, dosed actives - hyaluronic acid, lysine and vitamin C - to help in collagen and connective tissue formation, and to help in the development and maintenance of bones and cartilage. Health Canada licensed Natural Health Product, NPN 80028874. Licensed Natural Health Product NPN 80028874.
Une capsule végétalienne combinant trois ingrédients actifs réels et dosés - acide hyaluronique, lysine et vitamine C - pour aider à la formation du collagène et du tissu conjonctif, et pour aider au développement et au maintien des os et du cartilage. Produit de santé naturel homologué par Santé Canada, NPN 80028874.
Hyaluronic Acid, Lysine & Vitamin C - Real Doses, One Capsule
98.5 mg hyaluronic acid, 75 mg lysine and 50 mg vitamin C per vegan capsule - Non-GMO, Gluten-Free, Made in Canada
Backed by real research
Oral hyaluronic acid, vitamin C's role in collagen synthesis, and lysine's structural role in collagen cross-linking are each independently studied areas of published research.
The AOR difference
A vegan capsule with three real, dosed actives and a short, transparent ingredient list - made in Canada to GMP standards.
Advanced Ingredients, Superior Results
Three real, dosed actives working together - here is what each one contributes and what the wider research base says about them.
Hyaluronic Acid
A naturally occurring component of skin and connective tissue that helps maintain tissue hydration and works alongside lysine and vitamin C to support collagen and connective tissue formation.
98.5 mg per capsuleLysine
An essential amino acid the body cannot make on its own; Health Canada recognizes lysine's role in collagen formation, a foundational building block for connective tissue.
75 mg per capsule, as L-Lysine monohydrochloride
Vitamin C
An antioxidant vitamin that helps in collagen formation, helps maintain and support the immune system, helps in wound healing, and helps in the development and maintenance of bones and cartilage.
50 mg per capsuleAOR Lysine HA Vitamin C: Supplement Facts
Medicinal Ingredients (per capsule)
- Hyaluronic Acid98.5 mg
- Lysine as L-Lysine monohydrochloride75 mg
- Vitamin C50 mg
Non-Medicinal Ingredients: Non-medicinal ingredients: microcrystalline cellulose, sodium stearyl fumarate, hyprolose. Capsule: hypromellose.
Recommended Use or Purpose: Helps in collagen and connective tissue formation. Helps in the development and maintenance of bones and cartilage. Vitamin C maintains and supports good health. Helps with immune system. Helps in wound healing.
Recommended Dose (Adults 18 years and older): Take 1 capsule, twice daily, with or without food, or as directed by a qualified health care practitioner. Do not crush, blend or mix the capsules. Swallow the capsules whole. Do not exceed the daily dose unless instructed by a health care practitioner.
Cautions and Warnings: Allergens: Corn. Consult a health care practitioner prior to use if you are following a low protein diet. Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Do not use if safety seal is broken. Store tightly sealed in a cool, dry place. Known Adverse Reactions: None known.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Ingrédients médicinaux (par capsule)
- Acide hyaluronique98.5 mg
- Lysine sous forme de monochlorhydrate de L-Lysine75 mg
- Vitamine C50 mg
Ingrédients non médicinaux : Ingrédients non médicinaux : cellulose microcristalline, stéarylfumarate de sodium, hyprolose. Capsule : hypromellose.
Usage ou fins recommandés : Aide à la formation du collagène et du tissu conjonctif. Aide au développement et au maintien des os et du cartilage. La vitamine C maintient et soutient une bonne santé. Aide le système immunitaire. Aide à la cicatrisation des blessures.
Dose recommandée (adultes de 18 ans et plus) : Prendre 1 capsule, deux fois par jour, avec ou sans nourriture, ou selon les recommandations d'un praticien de soins de santé qualifié. Ne pas écraser, broyer ni mélanger les capsules. Avaler les capsules entières. Ne pas dépasser la dose quotidienne sauf indication contraire d'un professionnel de la santé.
Mises en garde et précautions : Allergènes : maïs. Consultez un professionnel de la santé avant l'utilisation si vous suivez un régime pauvre en protéines. Consultez un praticien de soins de santé avant l'utilisation si vous êtes enceinte ou si vous allaitez. Ne pas utiliser si le sceau de sécurité est brisé. Conserver hermétiquement fermé dans un endroit frais et sec. Réactions indésirables connues : aucune connue.
NPN 80028874
Support collagen, skin and connective tissue the simple way
Get AOR Lysine, Hyaluronic Acid with Vitamin C on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy AOR Lysine, Hyaluronic Acid with Vitamin C
Three real, dosed actives in one vegan capsule - for collagen, connective tissue, bones, cartilage and immune support.
Three Real Actives, One Capsule
98.5 mg hyaluronic acid, 75 mg lysine and 50 mg vitamin C per capsule - no proprietary blends, no guessing.
Collagen & Connective Tissue
Helps in collagen and connective tissue formation, and in the development and maintenance of bones and cartilage.
Immune Support & Wound Healing
Vitamin C helps maintain and support the immune system, and helps in wound healing.
Premium Canadian Brand
AOR - Advanced Orthomolecular Research, since 1991. NPN 80028874.
Inside every capsule
Hyaluronic acid, lysine and vitamin C together in one vegan capsule - real per-capsule doses of 98.5 mg hyaluronic acid, 75 mg lysine and 50 mg vitamin C.
How to use
Take 1 capsule, twice daily
Adults 18 years and older: take 1 capsule, twice daily, with or without food.
Swallow whole
Do not crush, blend or mix capsules - swallow capsules whole.
Don't exceed the daily dose
Do not exceed the daily dose unless instructed by a qualified health care practitioner.
Check with your practitioner
Consult a health care practitioner before use if you are pregnant, breastfeeding, or following a low protein diet.
What the research says about the ingredients
Peer-reviewed studies and reviews on the individual ingredients in this formula - hyaluronic acid, lysine and vitamin C. Shared for education, not as claims about this finished product. AOR Lysine, Hyaluronic Acid with Vitamin C's claims are the statements authorized under its Natural Health Product licence, NPN 80028874.
Pilot trial of oral hyaluronic acid for knee osteoarthritis quality of life
In a pilot randomized double-blind trial, 20 adults with knee osteoarthritis took 80 mg per day of oral hyaluronic acid or placebo for 8 weeks; the primary pain score did not differ significantly between groups, but the hyaluronic acid group showed numerically larger improvements in physical function and several quality-of-life measures.
Human RCTShort-term oral hyaluronate eased knee osteoarthritis symptoms
In a randomized, double-blind, placebo-controlled trial, 60 adults with knee osteoarthritis given an oral sodium hyaluronate spanning a broad molecular-weight range for 56 days showed significant improvements in pain, WOMAC score and joint range of motion, plus reduced use of anti-inflammatory and pain medication versus placebo.
Human RCTOral hyaluronic acid tablet compared with a glucosamine-chondroitin supplement
In a randomized pilot study of adults with mild-to-moderate knee osteoarthritis, four weeks of a daily oral hyaluronic acid tablet (300 mg) produced significantly greater reductions in pain at rest and during movement than a glucosamine-plus-chondroitin comparator, with both groups showing improved WOMAC scores.
Human RCTMeta-analysis: oral hyaluronic acid measurably improves skin hydration, elasticity and wrinkles
Pooling 7 randomized controlled trials, this meta-analysis found statistically significant improvements in skin hydration, elasticity and wrinkle depth with oral hyaluronic acid supplementation versus placebo, with a general trend toward improvement in firmness and transepidermal water loss as well.
Meta-analysis12 weeks of oral hyaluronan reduced wrinkles and improved dry skin
In a 12-week, double-blind, placebo-controlled trial, 40 healthy adults taking 120 mg per day of oral hyaluronan showed significant improvements in wrinkle assessment, stratum corneum water content, transepidermal water loss and skin elasticity compared with placebo.
Human RCTWhy skin hyaluronic acid loss drives visible aging
This review explains that hyaluronic acid maintains skin hydration, elasticity and firmness as a key extracellular matrix component, and that its age-related decline reduces water-binding capacity and contributes to drier, less elastic, more wrinkled skin - the physiological basis for hydration-focused hyaluronic acid supplementation.
ReviewVitamin C-enriched supplementation increased collagen synthesis markers
In a randomized, double-blind, crossover trial, healthy adults given vitamin C-enriched gelatin before intermittent exercise showed increased circulating collagen-building amino acids, and those taking the higher dose showed roughly double the blood marker of new type I collagen synthesis compared with placebo.
Human RCTVitamin C is required at every stage of collagen-dependent wound healing
This review describes how vitamin C is needed throughout the wound-healing process, contributing to the synthesis, maturation, secretion and degradation of collagen during the proliferative phase, with tissue vitamin C levels dropping after injury as the body prioritizes collagen repair.
ReviewVitamin C increased collagen production in human skin tissue
Using human skin explants, researchers showed that a vitamin C derivative significantly increased epidermal thickness and favoured production of type III collagen after 10 days of application, directly demonstrating vitamin C's role in stimulating collagen biosynthesis in living skin tissue.
Lab studyLysine is chemically modified to build collagen's cross-linked structure
This review details how specific lysine residues in collagen are hydroxylated and then glycosylated during biosynthesis, before undergoing reactions outside the cell that form the covalent cross-links giving mature collagen its strength and stability.
ReviewLysine hydroxylation is the first committed step in collagen cross-linking
This methods review explains that hydroxylation of specific lysine residues by lysyl hydroxylase enzymes is the critical first modification determining how collagen molecules subsequently glycosylate and cross-link into stable fibrils in the extracellular space.
ReviewLysine hydroxylation strengthens the cartilage matrix during bone formation
Published in Nature, this study found that increased proline and lysine hydroxylation on collagen made the cartilage matrix more resistant to enzymatic degradation, a metabolically-driven modification that increased bone mass during growth-plate cartilage formation.
Animal studyAdding hyaluronic acid to a collagen-and-vitamin-C supplement: an honest look
In a 16-week randomized, double-blind, placebo-controlled trial, both a collagen-plus-vitamin-C supplement and a collagen-plus-vitamin-C-plus-hyaluronic-acid combination significantly improved dermis density, skin texture and wrinkle severity versus placebo - though this study could not confirm that adding hyaluronic acid improved elasticity or hydration beyond collagen and vitamin C alone.
Human RCTA hyaluronic acid, vitamin C and collagen combination for joint-related pain
In a randomized trial of adults with chronic low back pain linked to osteoarthritis, combining exercise therapy with daily oral collagen peptides, vitamin C, sodium hyaluronate, manganese and copper produced more durable improvements in pain and disability scores than exercise therapy alone, with benefits still present 6 weeks after treatment ended.
Human RCTHyaluronic acid's role across combination nutricosmetic formulas
This review of hyaluronic acid's cosmetic and nutricosmetic applications describes how HA-based formulations work through soft-tissue hydration and collagen and elastin stimulation, supporting its inclusion alongside complementary nutrients in combination products aimed at skin and connective tissue support.
ReviewAn oral lower-molecular-weight hyaluronic acid joint complex was well tolerated
In a 12-week multicenter randomized controlled trial, a daily oral joint supplement containing lower-molecular-weight hyaluronic acid (with krill oil and astaxanthin) produced significantly fewer adverse events than placebo (4% versus 16%), with mild gastrointestinal complaints the most common finding in both groups.
Human RCTEstablished tolerable intake levels for supplemental lysine
This narrative review of human dose-response trials found supplemental lysine well tolerated in healthy adults, establishing a no-observed-adverse-effect level of 6 grams per day and a lowest-observed-adverse-effect level of 7.5 grams per day - far above typical supplement doses such as this product's 150 mg daily total.
ReviewVitamin C is safe across a broad range of intakes
Reviewing the clinical trial evidence, this analysis concluded that vitamin C supplements are safe for most adults at intakes up to 2,000 mg per day, with no consistent pattern of adverse effects reported at any studied intake beyond occasional mild gastrointestinal upset at very high doses.
ReviewMolecular weight determines whether hyaluronic acid can penetrate skin's outer layer
Using Raman spectroscopy imaging, this study found that low molecular weight hyaluronic acid (20-300 kDa) was able to pass through the skin's stratum corneum barrier, while high molecular weight hyaluronic acid (1000-1400 kDa) could not penetrate at all.
Lab studyMolecular weight is a key variable separating hyaluronic acid product outcomes
This systematic review found that hyaluronic acid's molecular weight was a major driver of differences in joint outcomes across products, with higher molecular weight preparations generally associated with superior pain relief in the studies reviewed.
Systematic reviewGut bacteria and molecular weight together control oral hyaluronic acid's fate
Comparing germ-free and conventional mice, researchers found that gut bacteria were required to break oral hyaluronic acid into small fragments the intestine could absorb, and that only a small fraction (about 0.2%) of ingested hyaluronic acid became bioavailable - suggesting oral hyaluronic acid's benefits work mainly through systemic regulatory signaling rather than direct delivery to skin or joints.
Animal studyCollagen: the extracellular matrix's most abundant structural family
This foundational review describes how more than 20 distinct collagen types form the fibrillar and microfibrillar networks that give the extracellular matrix, connective tissue and basement membranes their structural integrity throughout the body.
ReviewA classic account of how collagen, hyaluronic acid and elastin build tissue
This landmark review of the extracellular matrix describes how collagen, hyaluronic acid, elastin and proteoglycans assemble into the macromolecular scaffolding that shapes connective tissue and guides cell differentiation during development.
ReviewImaging how collagen's molecular structure builds tissue architecture
This review explains how second-harmonic generation microscopy allows researchers to directly observe collagen organization across scales, from individual molecules up to the tissue-level architecture that gives connective tissue its mechanical properties.
ReviewFrequently asked questions
What is AOR Lysine, Hyaluronic Acid with Vitamin C for?
It is a Health Canada-licensed Natural Health Product that helps in collagen and connective tissue formation, helps in the development and maintenance of bones and cartilage, helps maintain and support the immune system, and helps in wound healing.
How do I take it?
Adults 18 years and older take 1 capsule, twice daily, with or without food, or as directed by a qualified health care practitioner. Swallow capsules whole; do not crush, blend or mix. Do not exceed the daily dose unless instructed by a health care practitioner.
How much of each ingredient is in a capsule?
Each capsule provides 98.5 mg hyaluronic acid, 75 mg lysine (as L-lysine monohydrochloride) and 50 mg vitamin C.
Is this the same product as AOR's L-Lysine cold sore support capsules?
No. This product provides 75 mg of lysine combined with hyaluronic acid and vitamin C for collagen, connective tissue, bone and cartilage support (NPN 80028874). AOR's separate L-Lysine product provides 500 mg of lysine alone and is licensed specifically to help reduce the recurrence, severity and healing time of cold sores (NPN 80002854) - a different, much higher dose under its own separate licence. Always check the NPN and label of the specific product you are taking.
What else is in the capsule?
Just three non-medicinal ingredients - microcrystalline cellulose, sodium stearyl fumarate and hyprolose - in a hypromellose (vegan) capsule shell.
How long does one bottle last?
The 60-capsule bottle is a 30-day supply and the 120-capsule bottle is a 60-day supply, both at 1 capsule twice daily.
Is it made in Canada?
Yes. It is manufactured in Canada in a GMP-compliant facility and licensed by Health Canada under NPN 80028874.
Are there any cautions?
Consult a health care practitioner before use if you are pregnant or breastfeeding, or if you are following a low protein diet. Allergen note: this product contains corn.
Support collagen, skin and connective tissue the simple way
Get AOR Lysine, Hyaluronic Acid with Vitamin C on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80028874. Helps in collagen and connective tissue formation. Helps in the development and maintenance of bones and cartilage. Vitamin C maintains and supports good health, helps with immune system, and helps in wound healing. The research summaries below concern the individual ingredients (hyaluronic acid, lysine and vitamin C) generally and are educational - they are not claims about this finished product beyond its licensed use. Read and follow the label. Consult a health care practitioner before use if you are pregnant or breastfeeding, or if you are following a low protein diet. Results may vary.
Important information
Safety Information
Cautions and Warnings: Allergens: Corn. Consult a health care practitioner prior to use if you are following a low protein diet. Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Do not use if safety seal is broken. Store tightly sealed in a cool, dry place. Known Adverse Reactions: None known.
Indications
Recommended Use or Purpose: Helps in collagen and connective tissue formation. Helps in the development and maintenance of bones and cartilage. Vitamin C maintains and supports good health. Helps with immune system. Helps in wound healing.
Ingredients
Medicinal Ingredients (per capsule): Hyaluronic acid 98.5 mg; Lysine (as L-Lysine monohydrochloride) 75 mg; Vitamin C 50 mg. Non-medicinal Ingredients: microcrystalline cellulose, sodium stearyl fumarate, hyprolose. Capsule: hypromellose. Vegan, Non-GMO and gluten-free. Non-medicinal ingredients are subject to change - always read and follow the label.
Directions
Recommended Dose (Adults 18 years and older): Take 1 capsule, twice daily, with or without food, or as directed by a qualified health care practitioner. Do not crush, blend or mix the capsules. Swallow the capsules whole. Do not exceed the daily dose unless instructed by a health care practitioner.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.