AOR Liver Support 517mg - Milk Thistle NAC & Chanca Piedra | 90-180 Caps
Visit the AOR Store| Brand | AOR |
| Serving | 517 mg (1 capsule, 3 times daily) |
| Licensed Natural Health Product | NPN 80023799 |
| Quality Standards | GMP-compliant facility |
| Country | Made in Canada  |
About this item
- ADVANCED LIVER SUPPORT FORMULA: Combines Milk Thistle (Silybum marianum) dry extract, Phyllanthus amarus and N-Acetyl-L-cysteine (NAC) to help support healthy liver function.
- STANDARDIZED MILK THISTLE EXTRACT: 117 mg of milk thistle dry extract standardized to 40% silymarin (calculated as silibinin) per capsule - traditionally used in Herbal Medicine as a hepatoprotectant.
- NAC FOR ANTIOXIDANT SUPPORT: 200 mg of N-Acetyl-L-cysteine (NAC, vegan) per capsule - a source of an antioxidant that helps protect cells against the oxidative damage caused by free radicals.
- PHYLLANTHUS AMARUS 200 MG: A traditional botanical included alongside milk thistle and NAC in this three-ingredient liver-support formula.
- CONTAINS BROCCOLI EXTRACT: Each capsule also includes 100 mg of broccoli (Brassica oleracea) extract, a declared non-medicinal ingredient included for additional antioxidant support.
- NON-GMO & GLUTEN-FREE: A clean formula free of gluten and GMO ingredients, manufactured by AOR in Calgary, Canada under GMP-certified quality standards.
- SIMPLE 3-TIMES-DAILY DOSE: Take 1 capsule 3 times daily with meals providing protein; use for a minimum of three weeks to see beneficial effects.
- TWO CONVENIENT SIZES: Available in a 90-capsule, 30-day supply or a 180-capsule, 60-day supply, both licensed under NPN 80023799.
Product Description
Liver Support 517mg - Milk Thistle, Phyllanthus amarus & NAC
AOR Liver Support combines 117 mg of standardized Milk Thistle (40% silymarin) with 200 mg of Phyllanthus amarus and 200 mg of N-Acetyl-L-cysteine (NAC) per capsule to help support healthy liver function, plus broccoli extract for additional antioxidant support. Licensed Natural Health Product NPN 80023799.
AOR Support Hépatique combine 117 mg de chardon-Marie normalisé (40 % silymarine) avec 200 mg de Phyllanthus amarus et 200 mg de N-Acétyl-L-cystéine (NAC) par capsule pour aider à soutenir la fonction hépatique, plus un extrait de brocoli pour un soutien antioxydant additionnel. Produit de santé naturel homologué. NPN 80023799.
Three Real, Dosed Liver-Support Actives
Milk Thistle, Phyllanthus amarus and NAC per capsule - Non-GMO, Gluten-Free
Standardized 40% Silymarin Extract
Milk Thistle is standardized to its active silymarin content (calculated as silibinin) so every capsule delivers a consistent, traceable 117 mg dose.
Simple 3-Times-Daily Dose
Take 1 capsule 3 times daily with meals providing protein, fitting easily into a daily routine over a minimum 3-week course.
Advanced Ingredients, Superior Results
Three real, dosed medicinal ingredients - not a proprietary blend. Here is what each one is and why it is included.
Milk Thistle
A concentrated, standardized milk thistle extract traditionally used in Herbal Medicine as a hepatoprotectant to help support liver function.
Silybum marianum dry extract, 117 mg per capsule (40% silymarin, calculated as silibinin)Phyllanthus amarus
A traditional botanical included at a dedicated 200 mg dose alongside Milk Thistle and NAC as part of this formula's licensed liver-function claim.
200 mg per capsule
NAC
A source of an antioxidant that helps protect cells against the oxidative damage caused by free radicals.
N-Acetyl-L-cysteine (vegan), 200 mg per capsuleBroccoli Extract
A real, declared non-medicinal ingredient included alongside the formula's three medicinal actives for additional antioxidant support.
Brassica oleracea, 100 mg per capsule (non-medicinal ingredient)AOR Liver Support: Supplement Facts
Each capsule contains:
- Silybum marianum (Milk Thistle) dry extract 40% silymarin, calculated as silibinin117 mg
- Phyllanthus amarus200 mg
- N-Acetyl-L-cysteine (NAC, vegan)200 mg
- Brassica oleracea (Broccoli) extract non-medicinal ingredient100 mg
Non-Medicinal Ingredients: Maltodextrin (corn), dicalcium phosphate, silicon dioxide, sodium stearyl fumarate, citric acid, glycine, l-aspartic acid, rice and soy flour, tapioca dextrin, olive oil. Capsule: hypromellose.
Recommended Use or Purpose: Helps to support liver function. Contains ingredients that help to support liver function as well as antioxidants for the maintenance of good health. Silybum marianum (Milk Thistle) is traditionally used in Herbal Medicine as a hepatoprotectant/liver protectant to help support liver function. N-Acetyl-L-cysteine (NAC) is a source of an antioxidant that helps to protect cells against the oxidative damage caused by free radicals. Licensed Natural Health Product, NPN 80023799.
Recommended Dose (Adults 18 years and older): Take 1 capsule 3 times daily with meals providing protein, or as directed by a qualified health care practitioner. Recommended Duration of Use: Use for a minimum of three weeks to see beneficial effects.
Cautions and Warnings: Consult a health care practitioner prior to use if you have a liver disease, if you have kidney stones, or if symptoms persist or worsen after use. Do not crush, blend or mix the capsules. Contraindications: Do not use if you are pregnant or breastfeeding. Do not use if you are taking antibiotics or nitroglycerin. Known Adverse Reactions: Hypersensitivity, such as an allergy, is known to occur; if so, discontinue use. Keep out of reach of children. Store in a cool, dry place.
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.
Chaque capsule contient :
- Silybum marianum (chardon-Marie) extrait sec 40 % silymarine, calculée en silibinine117 mg
- Phyllanthus amarus200 mg
- N-Acétyl-L-cystéine (NAC, végane)200 mg
- Brassica oleracea (extrait de brocoli) ingrédient non médicinal100 mg
Ingrédients non médicinaux : Maltodextrine (maïs), phosphate dicalcique, dioxyde de silicium, stéaryl fumarate de sodium, acide citrique, glycine, acide l-aspartique, farine de riz et de soya, dextrine de tapioca, huile d'olive. Capsule : hypromellose.
Usage ou fins recommandés : Aide à soutenir la fonction hépatique. Contient des ingrédients qui aident à soutenir la fonction hépatique ainsi que des antioxydants pour le maintien d'une bonne santé. Silybum marianum (chardon-Marie) est traditionnellement utilisé en phytothérapie comme agent hépatoprotecteur/protecteur du foie pour aider à soutenir la fonction hépatique. La N-Acétyl-L-cystéine (NAC) est une source d'un antioxydant qui aide à combattre les dommages oxydatifs causés par les radicaux libres. Produit de santé naturel homologué, NPN 80023799.
Dose recommandée (adultes de 18 ans ou plus) : Prendre 1 capsule 3 fois par jour avec des repas contenant des protéines, ou selon les recommandations d'un professionnel de la santé qualifié. Durée d'utilisation recommandée : Utiliser pendant un minimum de trois semaines pour observer les effets bénéfiques.
Mises en garde : Consultez un professionnel de la santé avant l'utilisation si vous avez une maladie du foie, si vous avez des calculs rénaux, ou si les symptômes persistent ou s'aggravent. Ne pas écraser, broyer ou mélanger les capsules. Contre-indications : Ne pas utiliser si vous êtes enceinte ou si vous allaitez. Ne pas utiliser si vous prenez des antibiotiques ou de la nitroglycérine. Réactions indésirables connues : Une hypersensibilité (allergie) est connue pour survenir; le cas échéant, cesser l'utilisation. Garder hors de la portée des enfants. Conserver dans un endroit frais et sec.
NPN 80023799
Add AOR Liver Support to your daily routine
Get AOR Liver Support on Amazon.ca - fast, protected delivery.
Get it on Amazon.caWhy AOR Liver Support
Three real, dosed ingredients for liver function support - premium AOR quality.
Three real, dosed ingredients
Milk Thistle 117 mg, Phyllanthus amarus 200 mg and NAC 200 mg per capsule - no proprietary blend, no filler herbs.
Standardized silymarin extract
Milk Thistle is standardized to 40% silymarin (calculated as silibinin), for consistent potency capsule to capsule.
Liver function & antioxidant support
Formulated to help support liver function and provide antioxidants for the maintenance of good health.
Premium Canadian brand
AOR - Advanced Orthomolecular Research, since 1991. Licensed Natural Health Product, NPN 80023799.
Inside every capsule
Three real, dosed liver-support actives - Milk Thistle 117 mg, Phyllanthus amarus 200 mg and NAC 200 mg - plus broccoli extract, in one capsule taken three times daily.
How to use it
1 capsule, 3 times daily
Adults take 1 capsule 3 times per day with meals providing protein, or as directed by a qualified health care practitioner.
Swallow capsules whole
Do not crush, blend or mix the capsules.
Give it at least 3 weeks
Use for a minimum of three weeks to see beneficial effects, then continue as part of your daily routine.
What the research says about Milk Thistle, NAC and Phyllanthus
Peer-reviewed studies on Milk Thistle/silymarin, N-Acetyl-L-cysteine (NAC) and Phyllanthus - the medicinal ingredients in this formula - verified via PubMed. These summaries are educational and concern the ingredients generally; they are not claims about this finished product. This product's own claim is the statement authorized under its Natural Health Product licence, NPN 80023799: helps to support liver function, with antioxidants for the maintenance of good health.
An efficacious, tolerable option across chronic liver disease
A 2024 review of silymarin's use across chronic liver disease (fatty liver, drug-induced and alcoholic liver injury) concluded milk thistle extract exerts hepatoprotective, antioxidant, anti-inflammatory and antifibrotic effects, describing it as an efficacious, tolerable herbal option for supporting liver activity.
ReviewReduced liver weight in a NASH animal model
In the STAM mouse model of nonalcoholic steatohepatitis, milk thistle extract significantly decreased liver weight and the liver-to-body-weight ratio versus vehicle, with a numerical decrease in steatosis score at the higher dose.
Animal modelFrom folk 'liver tonic' to a well-characterized hepatoprotectant
A pharmacology-to-clinic review traces silymarin's antioxidative, anti-lipid-peroxidative, antifibrotic, anti-inflammatory, membrane-stabilizing and liver-regenerating mechanisms, noting a good safety profile and long history of use across toxic and drug-induced liver conditions.
ReviewThe established antidote for acetaminophen overdose
A classic clinical review describes N-acetylcysteine as the treatment of choice for acetaminophen overdose, noting that with timely NAC therapy, morbidity can be held to a minimum and mortality is rare in treated patients.
ReviewAcetylcysteine remains the frontline hepatotoxicity antidote
A 2023 review of paracetamol (acetaminophen) overdose describes acetylcysteine as an effective antidote against the dose-dependent hepatotoxicity that overdose can cause, while cataloguing the global burden of paracetamol-related liver injury.
ReviewA 2023 multi-society consensus on NAC dosing and safety
Four North American clinical toxicology societies developed a consensus statement detailing acetylcysteine dosing, monitoring, adverse effects and stopping criteria for the management of acetaminophen poisoning, reflecting decades of accumulated clinical experience with NAC.
Consensus statementA traditional herb studied for liver, kidney and more
A comprehensive ethnopharmacology review of Phyllanthus amarus catalogues its traditional use for stomach, genitourinary, liver, kidney and spleen complaints, and summarizes pharmacological studies reporting hepatoprotective, antioxidant and other bioactivities.
ReviewRaised glutathione and antioxidant enzymes against toxin-induced liver damage
In mice given the liver toxin aflatoxin B1, an ethanolic extract of Phyllanthus amarus lowered oxidative markers and raised reduced-glutathione levels along with glutathione peroxidase, glutathione-S-transferase, superoxide dismutase and catalase activity, with liver histology confirming the protective effect.
Animal modelHepatoprotective lignans found across the Phyllanthus genus
A 2025 review of the Phyllanthus genus (including P. amarus) identifies phyllanthin, hypophyllanthin and related compounds as key contributors to its hepatoprotective and antioxidant activity, historically used to help manage jaundice and liver disease.
ReviewCruciferous-vegetable compounds that switch on detox enzymes
In rats, plant-derived isothiocyanates related to sulforaphane - compounds found in broccoli and other Brassica vegetables - measurably increased tissue activity of the phase II detoxification enzymes glutathione S-transferase and quinone reductase, with the largest effect seen in the bladder.
Animal modelHow sulforaphane switches on the body's detox-enzyme program
A review of sulforaphane's chemopreventive activity describes its regulation of phase I and phase II drug-metabolizing enzymes through the Nrf2-Keap1 signaling pathway, a mechanism studied for its role in helping cells manage everyday chemical and environmental exposures.
ReviewAn emerging body of research on sulforaphane and liver health
A 2023 review of sulforaphane in liver disease summarizes evidence that it can help ameliorate hepatic steatosis, improve insulin sensitivity and attenuate oxidative liver injury across preclinical studies, while noting it has been well tolerated in the human studies conducted to date.
ReviewWell tolerated even at high doses over 24 weeks
An updated safety review found silymarin has no major toxicity in animal studies and is well tolerated in humans at therapeutic doses, including a high dose of 700 mg three times daily for 24 weeks, with occasional mild gastrointestinal effects like nausea or diarrhea.
ReviewNo liver-function changes at high doses in a rodent safety study
An acute oral toxicity study of an alkaloid-rich Phyllanthus amarus extract in mice found no biochemical derangement in liver function tests and no physical signs of toxicity even at the highest dose tested (5,000 mg/kg).
Animal modelIV NAC was generally well tolerated in a randomized trial
In a randomized, double-blind, placebo-controlled trial of intravenous N-acetylcysteine for acute liver failure, NAC was generally well tolerated; nausea and vomiting were the only adverse effects reported significantly more often than with placebo.
Human RCTHow silymarin ranks among seven natural NAFLD options
A network meta-analysis of 37 randomized trials (2,509 NAFLD patients) compared silymarin against curcumin, resveratrol, artichoke leaf extract, berberine, catechins and naringenin; artichoke leaf extract and naringenin ranked ahead of silymarin on some liver-enzyme and lipid measures, an honest reminder that no single botanical leads on every marker.
Network meta-analysisSilymarin among the more consistently effective dietary polyphenols
A systematic review and meta-analysis of eight dietary polyphenols in NAFLD found silymarin was effective in improving ALT and AST and in reducing hepatic fat accumulation and liver stiffness, in a field where several other polyphenols showed inconsistent results.
Meta-analysisAmong the herbal candidates furthest along in fatty-liver drug development
A review of herbal drug discovery for NAFLD/NASH highlights silymarin and berberine as the traditional-herbal-medicine-derived candidates that have advanced into FDA-sanctioned phase 4 clinical studies, ahead of many other botanical candidates surveyed.
ReviewHow the liver converts toxins into something the body can clear
A foundational review of hepatic drug metabolism explains the three-phase system by which the liver converts fat-soluble compounds into more water-soluble forms for elimination: phase I functionalization, phase II conjugation, and phase III transporter-mediated excretion.
ReviewPhase I and phase II detoxification, the liver's core defense system
A classic review of hepatic detoxification pathways describes how a wide variety of biotransforming enzymes catalyze the oxidation, reduction and hydrolysis (phase I) and conjugation (phase II) of drug and chemical molecules, broadening the liver's capacity to neutralize a vast range of everyday compounds.
ReviewWhy cysteine supply can be the limiting step in detoxification
A review of dietary modulation of the glutathione detoxification pathway explains that intracellular glutathione availability for conjugating and clearing xenobiotics is often limited by the supply of cysteine, the amino acid precursor synthesized through the gamma-glutamyl cycle.
ReviewTwo of this formula's actives studied together in severe cases
In a 20-year analysis of 2,108 hospitalized cases of amatoxin (mushroom) poisoning - a severe, unrelated medical emergency - silibinin (a milk thistle constituent) and N-acetylcysteine, used as single-agent treatments, were identified among the more effective specific therapies studied, out of ten regimens compared.
Retrospective analysisCombining the two outperformed supportive care alone in a large case review
A systematic review of 877 amatoxin-poisoning cases spanning 40 years found supportive care alone carried a 59% survival rate, while regimens combining N-acetylcysteine with silibinin were associated with an 85% survival rate in this severe, unrelated poisoning context.
Systematic reviewNo adverse pharmacokinetic interaction found when paired
A rat pharmacokinetic study found that pre-treatment with N-acetylcysteine plus silibinin, unlike some other combinations tested, did not significantly change how the body processed a test compound - an early signal that pairing the two does not disrupt normal metabolic handling.
Animal modelFrequently asked questions
What is AOR Liver Support?
A three-ingredient liver-support formula combining Milk Thistle (117 mg, 40% silymarin), Phyllanthus amarus (200 mg) and N-Acetyl-L-cysteine (NAC, 200 mg) per capsule, plus broccoli extract. It is a licensed Natural Health Product, NPN 80023799.
How do I take it?
Adults take 1 capsule 3 times per day with meals providing protein, or as directed by a qualified health care practitioner. Use for a minimum of three weeks to see beneficial effects.
What does Milk Thistle do in this formula?
Milk Thistle (Silybum marianum) is traditionally used in Herbal Medicine as a hepatoprotectant/liver protectant to help support liver function. This formula uses a standardized extract at 40% silymarin, calculated as silibinin.
What is Phyllanthus amarus?
Phyllanthus amarus is a botanical included in this formula at 200 mg per capsule alongside Milk Thistle and NAC, as part of AOR's licensed liver-function and antioxidant claim under NPN 80023799.
What does NAC do?
N-Acetyl-L-cysteine (NAC) is a source of an antioxidant that helps protect cells against the oxidative damage caused by free radicals.
Is there broccoli in this product?
Yes - each capsule contains 100 mg of broccoli (Brassica oleracea) extract, declared as a non-medicinal ingredient alongside the three medicinal actives.
Who should not use it?
Do not use if you are pregnant or breastfeeding, or if you are taking antibiotics or nitroglycerin. Consult a health care practitioner before use if you have a liver disease, if you have kidney stones, or if symptoms persist or worsen.
What sizes are available?
A 90-capsule bottle (a 30-day supply at 1 capsule 3 times daily) and a 180-capsule bottle (a 60-day supply), both licensed under NPN 80023799.
Add AOR Liver Support to your daily routine
Get AOR Liver Support on Amazon.ca - fast, protected delivery.
Get it on Amazon.caNatural Health Product NPN 80023799. Helps to support liver function; contains ingredients that help to support liver function as well as antioxidants for the maintenance of good health. Research summaries below concern the individual ingredients generally and are educational, not product-specific claims. Read and follow the label. Do not use if you are pregnant or breastfeeding, or if you are taking antibiotics or nitroglycerin. Consult a health care practitioner prior to use if you have a liver disease, if you have kidney stones, or if symptoms persist or worsen. AOR is the manufacturer; sold by Canadian Health & Care on Amazon.ca. Results may vary.
Important information
Safety Information
Cautions and Warnings: Consult a health care practitioner prior to use if you have a liver disease, if you have kidney stones, or if symptoms persist or worsen after use. Do not crush, blend or mix the capsules. Contraindications: Do not use if you are pregnant or breastfeeding. Do not use if you are taking antibiotics or nitroglycerin. Known Adverse Reactions: Hypersensitivity, such as an allergy, is known to occur; if so, discontinue use. Keep out of reach of children. Store in a cool, dry place.
Indications
Recommended Use or Purpose: Helps to support liver function. Contains ingredients that help to support liver function as well as antioxidants for the maintenance of good health. Silybum marianum (Milk Thistle) is traditionally used in Herbal Medicine as a hepatoprotectant/liver protectant to help support liver function. N-Acetyl-L-cysteine (NAC) is a source of an antioxidant that helps to protect cells against the oxidative damage caused by free radicals. Licensed Natural Health Product, NPN 80023799.
Ingredients
Medicinal Ingredients (per capsule): Silybum marianum (Milk Thistle) dry extract (40% silymarin, calculated as silibinin) 117 mg, Phyllanthus amarus 200 mg, N-Acetyl-L-cysteine (NAC, vegan) 200 mg. Non-medicinal Ingredients: Brassica oleracea (Broccoli) extract 100 mg, maltodextrin (corn), dicalcium phosphate, silicon dioxide, sodium stearyl fumarate, citric acid, glycine, l-aspartic acid, rice and soy flour, tapioca dextrin, olive oil. Capsule: hypromellose.
Directions
Recommended Dose (Adults 18 years and older): Take 1 capsule 3 times daily with meals providing protein, or as directed by a qualified health care practitioner. Recommended Duration of Use: Use for a minimum of three weeks to see beneficial effects.
Legal Disclaimer
Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.