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Amazon's Choice Health Canada NPN 80006852 Vegan / Non-GMO / Gluten Free 500 g - 33 servings
GlycineGlycine - benefits and key ingredients Glycine - lifestyleGlycine - ingredientsGlycine - supplement facts panel

AOR Glycine Powder - Amino Acid for Cognitive Function, Restful Sleep, Joint & Muscle Support - 500 g, 33 Servings, Vegan Non-GMO

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$33.48 CAD ($6.70 / 100 g)
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BrandAOR
ServingPowder (500 g)
Licensed Natural Health ProductNPN 80006852
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • SUPPORTS MENTAL CLARITY & COGNITIVE PERFORMANCE: A conditionally essential amino acid that plays a key role in supporting mental clarity and focus - appreciated for contributions to sharper memory and recall.
  • ENCOURAGES RESTFUL, REJUVENATING SLEEP: Glycine supports a more restful night's sleep, helping you fall asleep and stay asleep - waking refreshed and ready for the day.
  • SUPPORTS STRONG, ACTIVE LIFESTYLES: Foundational support for muscles, joints and connective tissues - for flexibility, mobility and vitality.
  • ENCOURAGES EMOTIONAL BALANCE & FOCUS: Supports a calm, composed mindset; glycine's role in neurotransmitter support may contribute to steadiness and focus.
  • A NATURALLY SWEET ADDITION: Lightly sweet glycine powder complements low-carb and keto plans - plant-based, gluten-free, non-GMO and vegan, without compromising flavour.

Customer Reviews

4.6 out of 5 · 434 global ratings
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Product Description

Glycine - Conditionally Essential Amino Acid

AOR Glycine Glycine

Supporting a wide range of healthy bodily functions. Pure, single-ingredient glycine in a convenient powder. The smallest and simplest amino acid, glycine is the second most-used building block for proteins and acts as a calming neurotransmitter in the brain and spinal cord. Licensed Natural Health Product NPN 80006852.

Soutenir un large éventail de fonctions corporelles saines. Glycine pure à ingrédient unique, en poudre pratique. Le plus petit et le plus simple des acides aminés. Produit de santé naturel homologué. NPN 80006852.

Glycine lifestyle
AOR Glycine Glycine
Premium - AOR

Pure Glycine Powder

Single-ingredient, naturally sweet and unflavored - Vegan, Non-GMO, Gluten Free

Naturally Sweet & Unflavored

Lightly sweet glycine blends easily into water, coffee or recipes - a versatile sugar alternative for low-carb and keto routines.

Flexible Powder Dosing

From 15 g (one tablespoon, about one serving) up to 60 g daily - reach therapeutic doses easily, without handfuls of capsules.

One Amino Acid, Many Benefits

Research supports a role for glycine across a wide range of healthy bodily functions - from cognition and sleep to muscle, joints and bone.

Cognitive Function

Supports mental clarity and focus; glycine acts as a neurotransmitter in the brain and spinal cord.

Restful Sleep

Known as a sleep molecule with a calming effect that positively impacts circadian rhythm.

Muscle Growth & Repair

A key building block for collagen and protein synthesis, supporting muscle growth and repair.

Joints & Connective Tissue

Foundational support for connective tissue, mobility and your body's structural needs.

Bone Health

Supports bone health, in part through insulin's anabolic effect on bone and muscle.

Mood & Emotional Balance

Acts as a calming neurotransmitter to support a steady, balanced mood and everyday focus.

AOR Glycine Glycine: Supplement Facts

AOR™Glycine
English

One Tablespoon contains:

  • Glycine~15 g

Non-Medicinal Ingredients: None.

Recommended Use or Purpose: Glycine is an amino acid that supports a wide range of healthy bodily functions.

Recommended Dose (Adults): Take 15-60 g (approximately one to four servings; one tablespoon is about 15 g) daily on an empty stomach, or as directed by a qualified health care practitioner. Recommended Duration of Use: Consult a health care practitioner for use beyond six weeks.

Cautions and Warnings: Consult a health care practitioner prior to use if you are pregnant, breastfeeding or following a low-protein diet. Discontinue use and consult a health care practitioner if digestive discomfort with nausea develops. Store in a cool, dry place, away from children.

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product.

Français

Une cuillère à soupe contient :

  • Glycine~15 g

Ingrédients non médicinaux : aucun.

Usage ou fins recommandés : la glycine est un acide aminé qui soutient un large éventail de fonctions corporelles saines.

Dose recommandée (adultes) : prendre 15 à 60 g (environ une à quatre portions) par jour à jeûn, ou selon les directives d'un praticien de soins de santé. Durée d'utilisation : consulter un praticien de soins de santé pour un usage au-delà de six semaines.

Mises en garde : consulter un praticien de soins de santé avant emploi en cas de grossesse, d'allaitement ou de régime faible en protéines. Cesser l'emploi et consulter un praticien si un inconfort digestif avec nausées se manifeste.

NPN 80006852

Naturally sweet & unflavoredOne amino acid, many benefitsVegan / Non-GMO / Gluten-FreeMade in Canada

Add AOR Glycine to your daily routine

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Why AOR Glycine

Pure, single-ingredient amino acid powder - premium AOR quality.

Single-ingredient purity

Just glycine, with no non-medicinal ingredients - naturally sweet and unflavored.

Cognition & sleep

Acts as a calming neurotransmitter supporting focus and restful sleep.

Muscle, joint & bone

A building block for collagen and protein synthesis.

Premium Canadian brand

AOR - Advanced Orthomolecular Research, since 1991. NPN 80006852.

Glycine powder vs. the alternatives

A flexible, single-ingredient amino acid in convenient powder form.

 AOR GlycineCapsule amino acidsSweeteners
FormPowder, flexible doseFixed-dose capsules-
Therapeutic dosing (15-60 g)EasyMany capsules-
Naturally sweetYesNoYes (no benefits)
Single ingredientYesVaries-
Health Canada NPNNPN 80006852Varies-

How to use it

15-60 g daily

Adults take 15-60 g (~ one to four servings; one tablespoon is about 15 g) daily on an empty stomach.

Mix into anything

Naturally sweet and unflavored - stir into water, coffee, smoothies or recipes.

Occasional or guided use

Consult a health-care practitioner for use beyond six weeks.

What the research says about glycine

Educational summaries of published research on glycine; not product-specific claims. AOR Glycine's claim is the traditional/authorized use under NPN 80006852.

Sleep

Fewer night awakenings from a glycine-rich peptide

In physically active men with sleep complaints, a glycine-rich collagen peptide taken before bed reduced polysomnography-recorded awakenings and improved next-morning cognitive performance.

Human RCT
Thomas et al., European Journal of Nutrition (2023)
Sleep

Sleep-promoting action traced to the brain's clock center

In rats, oral glycine promoted sleep and lowered core body temperature by acting on NMDA receptors in the suprachiasmatic nucleus, the brain's master circadian clock.

Mechanism
Kawai et al., Neuropsychopharmacology (2014)
Sleep

A safe amino-acid sleep strategy

Reviewed as shortening time to fall asleep and improving sleep quality without next-day grogginess.

Review
Bannai & Kawai, J. Pharmacological Sciences (2012)
Brain & nervous system

Raises a calming brain chemical after oral dosing

Oral glycine increased extracellular serotonin (but not dopamine) in the prefrontal cortex of rats, a possible mechanism behind its calming, sleep-supportive effects.

Mechanism
Bannai et al., Psychiatry and Clinical Neurosciences (2011)
Brain & nervous system

An inhibitory neurotransmitter

Glycine acts as an inhibitory neurotransmitter and an NMDA-receptor co-agonist in the brain and spinal cord.

Mechanism
Bowery & Smart, British Journal of Pharmacology (2006)
Brain & nervous system

Studied for memory & attention

Glycine has been studied for effects on memory and attention via NMDA-receptor modulation.

Human study
File, Fluck & Fernandes, J. Clinical Psychopharmacology (1999)
Energy & GlyNAC

Reduced fatigue, better performance

Glycine reduced fatigue and improved next-day psychomotor performance in sleep-restricted volunteers.

Human study
Bannai et al., Frontiers in Neurology (2012)
Energy & GlyNAC

Cognition in older adults (GlyNAC)

A 24-week pilot trial of glycine plus NAC improved cognition alongside metabolic and mitochondrial markers.

Pilot clinical trial
Kumar et al., Clinical & Translational Medicine (2021)
Energy & GlyNAC

Restored glutathione & insulin sensitivity

GlyNAC corrected glutathione deficiency, oxidative stress, mitochondrial dysfunction and insulin resistance over 24 weeks.

Pilot clinical trial
Kumar et al., Clinical & Translational Medicine (2021)
Collagen & skin

Glycine can limit collagen synthesis

Glycine availability can be a limiting factor for collagen synthesis; supplementation increased collagen production in vitro.

Research
de Paz-Lugo et al., Amino Acids (2018)
Collagen & skin

Collagen's most abundant amino acid

Glycine makes up roughly one third of the collagen molecule, the main structural protein of skin, tendon and bone.

Mechanism
Barbul, Journal of Nutrition (2008)
Collagen & skin

Skin is especially collagen-rich

Analysis of tissue composition found skin to be especially collagen-rich (an estimated 20-40% of protein), with glycine as collagen's single most abundant amino acid.

Research
Tarnutzer et al., Scientific Reports (2023)
Muscle, bone & repair

Collagen amino acids & healthy aging

A glycine-rich collagen amino-acid composition was associated with reduced biological age and improved healthspan markers.

Research
Dakhovnik et al., npj Aging (2025)
Muscle, bone & repair

Supported muscle strength (GlyNAC)

In the GlyNAC trial, supplementation improved muscle strength alongside metabolic markers in older adults.

Pilot clinical trial
Kumar et al., Clinical & Translational Medicine (2021)
Muscle, bone & repair

Helped preserve tissue after injury

In irradiated rats, dietary glycine helped preserve colon-wall thickness and the mucosal surface, supporting tissue repair after injury.

Research
de Aguiar Picanco et al., International Journal of Colorectal Disease (2011)
Metabolic & antioxidant

Helped metabolic-syndrome markers (RCT)

Oral glycine improved markers of oxidative stress and metabolic health in patients with metabolic syndrome.

Human RCT
Diaz-Flores et al., Canadian Journal of Physiology and Pharmacology (2013)
Metabolic & antioxidant

Roles in metabolic regulation (review)

Reviews glycine's roles in protein synthesis, metabolic regulation and cytoprotection.

Review
Perez-Torres et al., Mini Reviews in Medicinal Chemistry (2017)
Metabolic & antioxidant

Antioxidant & anti-inflammatory roles

Reviewed for roles in antioxidant defense, anti-inflammation and metabolic regulation.

Review
Razak et al., Oxid. Med. Cell. Longev. (2017)
Foundational nutrition

Why 'conditionally essential'

Endogenous glycine synthesis may not meet full metabolic demand, supporting dietary intake.

Review
Wang et al., Amino Acids (2013)
Foundational nutrition

A central one-carbon building block

Glycine feeds one-carbon metabolism and is a precursor for glutathione, creatine, heme and nucleotide synthesis.

Review
Adeva-Andany et al., Amino Acids (2017)
Foundational nutrition

Naturally sweet amino acid

Glycine is the simplest amino acid and was identified among the naturally sweet-tasting amino acids in human sensory testing.

Human study
Kawai, Okiyama & Ueda, Chemical Senses (2002)
Cytoprotection & safety

Cytoprotective in gut & liver

Glycine has shown cytoprotective effects in experimental models of gut and liver injury.

Research
Zhong et al., Curr. Opin. Clin. Nutr. Metab. Care (2003)
Cytoprotection & safety

Calms inflammatory signaling

Glycine activates glycine-gated chloride channels on immune cells, dampening inflammatory signaling.

Mechanism
Wheeler & Thurman, Cellular and Molecular Life Sciences (1999)
Cytoprotection & safety

Well tolerated even at high doses

In a clinical trial using glycine at roughly 0.8 g/kg bodyweight per day (about 50-60 g/day for most adults), treatment was well tolerated over six weeks.

Human RCT
Heresco-Levy et al., Archives of General Psychiatry (1999)

Customer Reviews

4.6 out of 5 · 434 global ratings
Read genuine reviews on Amazon →Available at Amazon

Frequently asked questions

How do I take AOR Glycine?

Adults take 15-60 g (~ one to four servings; one tablespoon is about 15 g) daily on an empty stomach, or as directed by a health-care practitioner. Consult a practitioner for use beyond six weeks.

What does it taste like?

Glycine is naturally, lightly sweet and unflavored - it dissolves easily in water, coffee or recipes and works as a low-carb sugar alternative.

Is it vegan and allergen-friendly?

Yes - vegan, non-GMO and gluten-free, with no non-medicinal ingredients (just glycine).

Who should not use it?

Consult a health-care practitioner before use if you are pregnant, breastfeeding or following a low-protein diet. Discontinue and consult a practitioner if digestive discomfort with nausea develops.

Naturally sweet & unflavoredOne amino acid, many benefitsVegan / Non-GMO / Gluten-FreeMade in Canada

Add AOR Glycine to your daily routine

Get AOR Glycine on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80006852. Glycine is an amino acid that supports a wide range of healthy bodily functions. Research summaries concern glycine generally and are educational, not product-specific claims. Read and follow the label. Consult a health-care practitioner before use if you are pregnant, breastfeeding, following a low-protein diet, or for use beyond six weeks. AOR is the manufacturer; sold by Canadian Health & Care on Amazon.ca. Results may vary.

Important information

Safety Information

Cautions and Warnings: Consult a health care practitioner prior to use if you are pregnant, breastfeeding or following a low-protein diet. Discontinue use and consult a health care practitioner if digestive discomfort with nausea develops. Store in a cool, dry place, away from children.

Indications

Recommended Use or Purpose: Glycine is an amino acid that supports a wide range of healthy bodily functions.

Ingredients

Medicinal ingredient: Glycine (15 g per tablespoon). Non-medicinal ingredients: None.

Directions

Recommended Dose (Adults): Take 15-60 g (approximately one to four servings; one tablespoon is about 15 g) daily on an empty stomach, or as directed by a qualified health care practitioner. Recommended Duration of Use: Consult a health care practitioner for use beyond six weeks.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product.

$33.48 CAD4.6 ★ (434) Get it on Amazon →