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Health Canada NPN 80126260 147 mg Reducose Mulberry Leaf Extract Vegan · Non-GMO · Gluten-Free 30 Capsules - 30-Day Supply
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AOR GlucoSupport - Reducose Mulberry Leaf for Blood Glucose Support | 30 Caps

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$38.52 CAD
Get it on Amazon.ca
BrandAOR
Serving147 mg (1 capsule)
Licensed Natural Health ProductNPN 80126260
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • SUPPORTS HEALTHY BLOOD SUGAR LEVELS: Reducose Mulberry Leaf Extract (Morus alba) helps support healthy glucose metabolism and contributes to normal blood sugar levels.
  • PROMOTES A HEALTHY INSULIN RESPONSE: Standardized to 8.5% 1-Deoxynojirimycin (DNJ), Reducose supports a healthy insulin response as part of everyday blood sugar support.
  • TAKE BEFORE A CARBOHYDRATE-RICH MEAL: One capsule taken before a carbohydrate-rich meal is how DNJ is designed to work - alongside a meal, not as a stand-alone treatment.
  • HIGH-POTENCY, CONCENTRATED EXTRACT: 147 mg of native Reducose extract per capsule, standardized to 8.5% DNJ - equivalent to 250 mg of a 5% DNJ standardized extract.
  • SIMPLE, SINGLE-INGREDIENT FORMULA: Just Reducose Mulberry Leaf Extract with L-Leucine, maltodextrin, microcrystalline cellulose and sodium stearyl fumarate - no unnecessary fillers.
  • ONE CAPSULE, ONCE DAILY: Take 1 capsule daily before a carbohydrate-rich meal - 30 capsules provide up to a 30-day supply, for occasional use.
  • VEGAN, NON-GMO & GLUTEN-FREE: A clean, vegan formula in a hypromellose (vegetable) capsule - non-GMO and gluten-free.
  • PREMIUM CANADIAN QUALITY: Made in Canada by Advanced Orthomolecular Research (AOR), GMP-compliant and licensed under Health Canada NPN 80126260.

Product Description

Reducose Mulberry Leaf Extract - Support for Healthy Blood Sugar Levels

AOR GlucoSupport

A concentrated 147 mg dose of Reducose, a patented mulberry leaf extract (Morus alba) standardized to 8.5% 1-Deoxynojirimycin (DNJ). AOR GlucoSupport helps support healthy glucose metabolism and promotes a healthy insulin response, taken before a carbohydrate-rich meal, in one small vegan capsule. Licensed Natural Health Product NPN 80126260.

Une dose concentrée de 147 mg de Reducose, un extrait breveté de feuille de mûrier (Morus alba) normalisé à 8,5 % de 1-désoxynojirimycine (DNJ). AOR GlucoSupport aide à soutenir un métabolisme sain du glucose et favorise une réponse insulinique saine, pris avant un repas riche en glucides, en une seule petite capsule végétalienne. Produit de santé naturel homologué. NPN 80126260.

GlucoSupport lifestyle
AOR GlucoSupport
Premium - AOR

AOR GlucoSupport - Reducose Mulberry Leaf Extract

Single-ingredient, vegan capsules - Non-GMO, Gluten-Free

High-Potency 147 mg Dose

One capsule delivers 147 mg of native Reducose Mulberry Leaf Extract, standardized to 8.5% DNJ - equivalent to 250 mg of a 5% DNJ standardized extract.

Designed to Work With Your Meal

Take 1 capsule before a carbohydrate-rich meal - DNJ is intended to act as you eat, not as a stand-alone treatment or on an empty stomach.

What Reducose Mulberry Leaf Extract Supports

Mulberry leaf extract and its DNJ content have been studied for their role in blood glucose metabolism - here is what the research explores.

Glucose Metabolism

Helps support healthy glucose metabolism and contributes to normal blood sugar levels.

Insulin Response

Promotes a healthy insulin response as part of everyday blood sugar support.

Carbohydrate Digestion Support

DNJ is studied for its role at the point where dietary carbohydrates are digested and absorbed, when taken with a meal.

Trusted, Concentrated Extract

A highly concentrated, standardized extract (8.5% DNJ) in a simple, vegan, single-ingredient capsule.

AOR GlucoSupport: Supplement Facts

AOR™GlucoSupport
English

Each Capsule contains:

  • Reducose Mulberry Leaf Extract (Morus alba) (8.5% 1-Deoxynojirimycin)147 mg

Non-Medicinal Ingredients: L-Leucine, maltodextrin (corn), microcrystalline cellulose and sodium stearyl fumarate. Capsule: hypromellose. NMIs are subject to change - always read and follow the label.

Recommended Use or Purpose: Helps support healthy glucose metabolism. Helps support healthy blood glucose (blood sugar) levels. Helps support a healthy insulin response.

Recommended Dose (Adults 18 years and over): Take 1 capsule per day before a carbohydrate-rich meal, or as directed by a health care practitioner. Do not open the capsules, as this may compromise the stability of the medicinal ingredients. Recommended Duration of Use: For occasional use only.

Cautions and Warnings: Consult a health care practitioner prior to use if you have cardiovascular disease, diabetes, or are taking antihyperglycemic medications or insulin. Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Consult a health care practitioner prior to use if you are taking steroids, protease inhibitors, or antipsychotics. Known Adverse Reactions/Allergen: Do not use if you have an allergy to the Moraceae family or corn. Do not use if the safety seal is broken. Keep out of reach of children. Store in a cool, dry place.

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings and directions before using or consuming a product. Manufactured by Advanced Orthomolecular Research (AOR), Calgary, Alberta. This item is sold and shipped by Amazon.ca.

Français

Chaque capsule contient :

  • Extrait de feuille de mûrier Reducose (Morus alba) (8,5 % de 1-désoxynojirimycine)147 mg

Ingrédients non médicinaux : L-Leucine, maltodextrine (maïs), cellulose microcristalline et fumarate de stéaryle sodique. Capsule : hypromellose. Les ingrédients non médicinaux peuvent changer - toujours lire et suivre l'étiquette.

Usage ou fins recommandés : Contribue à un métabolisme sain du glucose. Contribue à une glycémie saine. Favorise une réponse insulinique saine.

Dose recommandée (adultes de 18 ans et plus) : Prendre une capsule par jour avant un repas riche en glucides, ou selon les directives d'un praticien de soins de santé. Ne pas ouvrir les capsules, car cela pourrait compromettre la stabilité des ingrédients médicinaux. Durée d'utilisation recommandée : pour usage occasionnel seulement.

Mises en garde et précautions : Consulter un praticien de soins de santé avant d'en faire l'usage si vous souffrez d'une maladie cardiovasculaire, de diabète ou si vous prenez des médicaments antihyperglycémiques ou de l'insuline. Consulter un praticien de soins de santé avant d'en faire l'usage si vous êtes enceinte ou si vous allaitez. Consulter un praticien de soins de santé avant d'en faire l'usage si vous prenez des stéroïdes, des inhibiteurs de protéase ou des antipsychotiques. Réactions indésirables connues/Allergène : Ne pas utiliser en cas d'allergie à la famille des Moraceae ou au maïs. Ne pas utiliser si le sceau de sécurité est brisé. Garder hors de la portée des enfants. Conserver dans un endroit frais et sec.

NPN 80126260

147 mg Reducose Mulberry Leaf Extract per capsule30 capsules · 30-day supplyVegan · Non-GMO · Gluten-FreeMade in Canada

Support healthy blood sugar levels every day

Get AOR GlucoSupport on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why AOR GlucoSupport

A concentrated, single-ingredient Reducose Mulberry Leaf Extract supplement - premium AOR quality.

High-potency single ingredient

147 mg of Reducose Mulberry Leaf Extract (8.5% DNJ) per capsule, with minimal non-medicinal ingredients.

Glucose & insulin support

Helps support healthy glucose metabolism and promotes a healthy insulin response.

Designed for mealtime use

Taken before a carbohydrate-rich meal, matching how DNJ is studied to work.

Premium Canadian brand

AOR - Advanced Orthomolecular Research, since 1991. NPN 80126260.

How to use it

Take 1 capsule daily

Adults 18 years and over: take 1 capsule per day before a carbohydrate-rich meal, or as directed by a health care practitioner.

Best taken with a carb-rich meal

Take it right before the meal where you want blood-sugar support - DNJ is studied to act as carbohydrates are digested, not on an empty stomach.

For occasional use

For occasional use only. Do not open the capsules, as this may compromise the stability of the medicinal ingredients.

What the research says about mulberry leaf extract

Educational summaries of published research on mulberry leaf extract, its 1-Deoxynojirimycin (DNJ) content, and Reducose specifically where noted; not product-specific claims. AOR GlucoSupport's claim is the traditional/authorized use under NPN 80126260.

Reducose Mulberry Leaf Extract Research

Lower post-meal glucose and insulin across three doses

In a double-blind, randomised, crossover trial, healthy adults given 200, 225 or 250 mg of Reducose before a mixed meal showed significantly lower blood glucose and insulin responses than placebo, with glucose iAUC reduced by roughly 30-33%.

Human RCT
Thondre et al., Nutrients (2024)
Reducose Mulberry Leaf Extract Research

Improved glucose tolerance in a crossover trial

A double-blind, randomised crossover study found Reducose mulberry leaf extract improved glucose tolerance and lowered insulin concentrations compared with a reference product in normoglycaemic adults.

Human RCT
Lown et al., PLoS One (2017)
Reducose Mulberry Leaf Extract Research

Supported insulin secretion in cell and animal models

Reducose, together with its DNJ and L-leucine content, increased glucose-stimulated insulin secretion in pancreatic beta-cell (INS-1) cultures and lowered fasting blood glucose in a diabetic rat model, to an extent comparable with a metformin comparator.

Cell & animal study
Lee et al., Heliyon (2024)
DNJ & Alpha-Glucosidase Inhibition

Directly measured inhibition in humans

Using a 13C-sucrose breath test in healthy adults, Reducose dramatically impaired sucrose digestion versus placebo, providing direct in-human evidence of its intestinal sucrase/alpha-glucosidase-inhibiting mechanism.

Human study
Schillinger et al., Frontiers in Medicine (2022)
DNJ & Alpha-Glucosidase Inhibition

Protected cells under high-glucose stress

1-Deoxynojirimycin (DNJ) reduced high-glucose-accelerated cellular senescence in cultured human umbilical vein endothelial cells, pointing to a protective effect on blood-vessel cells under elevated glucose conditions.

Cell study
E et al., Experimental Gerontology (2014)
DNJ & Alpha-Glucosidase Inhibition

A reviewed mechanistic picture

A review of mulberry leaves in diabetes research describes multiple bioactive constituents - including DNJ, flavonoids and polysaccharides - acting through complementary mechanisms relevant to carbohydrate and glucose handling.

Review
Zhang et al., The American Journal of Chinese Medicine (2023)
Insulin Sensitivity Research

Improved insulin signaling in a diabetic rat model

Mulberry leaf multi-components, including DNJ, flavonoids and polysaccharides, improved insulin resistance in type 2 diabetic rats via the PI-3K/Akt insulin-signaling pathway.

Animal study
Zhang et al., Journal of Ethnopharmacology (2023)
Insulin Sensitivity Research

Linked to an insulin-resistance biomarker

In a 12-week supplementation study, mulberry-derived DNJ was associated with modulation of retinol-binding protein 4, a biomarker linked to insulin resistance, in people with prediabetes or early type 2 diabetes.

Human study
Fongsodsri et al., Nutrients (2022)
Insulin Sensitivity Research

Supported muscle mitochondrial function

Flavonoids extracted from mulberry leaf activated AMPK and improved skeletal muscle mitochondrial function in a type 2 diabetes model, a pathway closely tied to whole-body insulin sensitivity.

Animal study
Meng et al., Journal of Ethnopharmacology (2019)
Safety & Tolerability

No adverse effects at high doses over 90 days

A 90-day rat toxicology study of Reducose found no adverse effects on body weight, clinical pathology or organ histology at doses up to 2,550 mg/kg bodyweight per day, the highest dose tested.

Toxicology study
Murbach et al., Journal of Applied Toxicology (2024)
Safety & Tolerability

A wide margin of safety over 28 days

A 28-day repeated-dose toxicology study found no treatment-related adverse effects from Reducose at doses up to 4,000 mg/kg bodyweight per day in rats, the highest dose evaluated.

Toxicology study
Marx et al., International Journal of Toxicology (2016)
Safety & Tolerability

An honest look at allergy potential

A comprehensive review of DNJ notes that, while generally well tolerated, mulberry-family plants have been associated with allergic reactions including oral allergy syndrome and urticaria in sensitive individuals - consistent with label cautions for those with a Moraceae allergy.

Review
Tricase et al., Molecules (2025)
Comparative & Real-World Research

Meta-analysis across 12 clinical trials

A systematic review and meta-analysis of 12 randomized trials (615 participants) found mulberry leaf and mulberry leaf extract supplementation improved fasting blood glucose, HbA1c and fasting insulin versus control.

Meta-analysis
Cui et al., Food & Function (2023)
Comparative & Real-World Research

A placebo-controlled pilot study in type 2 diabetes

In adults with type 2 diabetes already on oral medication, a standardized mulberry leaf extract taken three times daily with meals was evaluated against placebo in a randomized, double-blind pilot study of glycemic and safety outcomes.

Human RCT
Riche et al., Complementary Therapies in Medicine (2017)
Comparative & Real-World Research

Mapping mulberry leaf's molecular targets

Proteomic analysis of skeletal muscle in a diabetic rat model identified multiple candidate molecular targets through which mulberry leaf extract may influence glucose handling, helping explain its multi-pathway effects.

Proteomics study
Shi et al., BMC Complementary Medicine and Therapies (2023)
Foundational Mulberry Leaf Phytochemistry

A comprehensive look at Morus alba chemistry

A 2025 review summarizes Morus alba's chemical composition, including DNJ, flavonoids and alkaloids, and its pharmacological properties and product development across functional foods and health products.

Review
Yan et al., Phytochemical Analysis (2025)
Foundational Mulberry Leaf Phytochemistry

Cataloguing white mulberry's bioactive compounds

A review of white mulberry's biosynthesis and pharmacology catalogues its major bioactive compound classes - flavonoids, phenolic acids, terpenoids and alkaloids - and their proposed health-related mechanisms.

Review
Fatima et al., Biology (2024)
Foundational Mulberry Leaf Phytochemistry

Reviewing the clinical and mechanistic picture

A review of mulberry leaf's clinical potential highlights consistent improvements in glucose-metabolism-related markers across human and animal studies, with mechanisms linked to gut microbiota, inflammation and oxidative stress.

Review
Tang et al., Journal of Ethnopharmacology (2023)
Dosing & Meal-Timing Research

Lowered the glycemic index of common carbohydrates

An exploratory crossover study found mulberry leaf extract reduced the glycemic index of four common dietary carbohydrates, consistent with DNJ's action on carbohydrate digestion at the point of a meal.

Human study
Wang et al., Medicine (2018)
Dosing & Meal-Timing Research

Timing of intake affects the postprandial response

A randomized, placebo-controlled study found the timing of acute mulberry leaf extract intake influenced its effect on postprandial glucose metabolism in healthy adults, underscoring why it is taken right before a meal.

Human RCT
Takahashi et al., European Journal of Clinical Nutrition (2023)
Dosing & Meal-Timing Research

A dose-response relationship in humans

A human crossover study using 0, 100 and 750 mg doses of Reducose found a clear dose-dependent effect on intestinal sucrase inhibition, supporting a meaningful dose-response relationship for this mechanism.

Human study
Brouwer et al., The Journal of Nutrition (2023)
Weight & Metabolic Marker Research

Improved glucose, weight and lipids together

In a type 2 diabetes mouse model, mulberry leaf water extract lowered fasting blood glucose and body weight while improving lipid profile and insulin-resistance markers.

Animal study
Du et al., Phytotherapy Research (2022)
Weight & Metabolic Marker Research

Reduced obesity-associated inflammation

A high-hydrostatic-pressure mulberry leaf extract reduced adipose tissue mass and markers of obesity-associated inflammation in high-fat-diet-fed rats.

Animal study
Ko et al., Journal of Medicinal Food (2022)
Weight & Metabolic Marker Research

Ameliorated obesity-related metabolic disorders

Mulberry twig and leaf extracts improved body-weight gain, lipid profile and insulin resistance (HOMA-IR) via gut microbiota modulation in a high-fat-diet mouse model of obesity.

Animal study
Qian et al., Animals (2025)

Frequently asked questions

What is Reducose Mulberry Leaf Extract and what does it do?

Reducose is a patented water extract of mulberry leaf (Morus alba) standardized to 8.5% 1-Deoxynojirimycin (DNJ). It helps support healthy glucose metabolism and promotes a healthy insulin response.

How do I take AOR GlucoSupport?

Adults 18 years and over take 1 capsule per day before a carbohydrate-rich meal, or as directed by a health care practitioner. For occasional use only.

Why take it before a carbohydrate-rich meal?

DNJ is studied for its role at the point where dietary carbohydrates are digested, so it is taken just before a carb-containing meal rather than at a fixed time of day.

How long does one bottle last?

30 capsules provide up to a 30-day supply at 1 capsule per day.

Is it vegan and allergen-friendly?

Yes - vegan, non-GMO and gluten-free, in a hypromellose (vegetable) capsule. Do not use if you have an allergy to the Moraceae (mulberry) family or corn.

Who should not use it?

Consult a health care practitioner prior to use if you have cardiovascular disease, diabetes, or are taking antihyperglycemic medications or insulin, if you are pregnant or breastfeeding, or if you are taking steroids, protease inhibitors or antipsychotics.

Is it made in Canada?

Yes - manufactured by Advanced Orthomolecular Research (AOR) in Calgary, Alberta, in a GMP-compliant facility, and licensed by Health Canada under NPN 80126260.

Where do I buy it?

Use the orange button on this page - it takes you to the AOR listing on Amazon.ca for secure checkout and fast delivery.

147 mg Reducose Mulberry Leaf Extract per capsule30 capsules · 30-day supplyVegan · Non-GMO · Gluten-FreeMade in Canada

Support healthy blood sugar levels every day

Get AOR GlucoSupport on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80126260. Reducose Mulberry Leaf Extract (Morus alba) provides support for healthy glucose metabolism and helps promote a healthy insulin response. The research summaries below concern mulberry leaf extract and its 1-Deoxynojirimycin (DNJ) content generally and are educational - they are not product-specific claims. Read and follow the label. Consult a health care practitioner before use if you have cardiovascular disease, diabetes, or are taking antihyperglycemic medications or insulin, if you are pregnant or breastfeeding, or if you are taking steroids, protease inhibitors or antipsychotics. Results may vary.

Important information

Safety Information

Cautions and Warnings: Consult a health care practitioner prior to use if you have cardiovascular disease, diabetes, or are taking antihyperglycemic medications or insulin. Consult a health care practitioner prior to use if you are pregnant or breastfeeding. Consult a health care practitioner prior to use if you are taking steroids, protease inhibitors, or antipsychotics. Known Adverse Reactions/Allergen: Do not use if you have an allergy to the Moraceae family or corn. Do not use if the safety seal is broken. Keep out of reach of children. Store in a cool, dry place.

Indications

Recommended Use or Purpose: Helps support healthy glucose metabolism. Helps support healthy blood glucose (blood sugar) levels. Helps support a healthy insulin response.

Ingredients

Medicinal Ingredient (per capsule): Reducose Mulberry Leaf Extract (Morus alba) (8.5% 1-Deoxynojirimycin) 147 mg (147 mg native extract is equivalent to 250 mg of a 5% DNJ standardized extract). Non-medicinal Ingredients: L-Leucine, maltodextrin (corn), microcrystalline cellulose and sodium stearyl fumarate. Capsule: hypromellose. NMIs are subject to change - always read and follow the label.

Directions

Recommended Dose (Adults 18 years and over): Take 1 capsule per day before a carbohydrate-rich meal, or as directed by a health care practitioner. Do not open the capsules, as this may compromise the stability of the medicinal ingredients. Recommended Duration of Use: For occasional use only.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings and directions before using or consuming a product. Manufactured by Advanced Orthomolecular Research (AOR), Calgary, Alberta. This item is sold and shipped by Amazon.ca.