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Health Canada NPN 80020741 Standardized 95% curcuminoids - 400 mg per capsule Vegan · Non-GMO · Gluten-Free Made in Canada - GMP facility
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AOR Curcumin 95 400mg - Standardized Turmeric Extract | 90 Caps

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$38.63 CAD
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BrandAOR
Serving3 capsules daily (90 per bottle)
Licensed Natural Health ProductNPN 80020741
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • STANDARDIZED 95% CURCUMINOIDS: Each vegan capsule delivers 400 mg of curcumin from an extract standardized to 95% curcuminoids from Curcuma longa (turmeric) rhizome - a pure, concentrated, single-ingredient formula.
  • TRADITIONALLY USED TO RELIEVE JOINT INFLAMMATION: Used in herbal medicine to help relieve joint inflammation, traditionally supporting joint comfort and mobility.
  • NATURAL ANTIOXIDANT SUPPORT: Provides antioxidants for the maintenance of good health, helping the body defend against everyday oxidative stress.
  • THE CLASSIC, STANDARDIZED FORM OF CURCUMIN: A plain, standardized 95% curcuminoid extract - the foundational form of curcumin studied in decades of research, without added absorption-enhancement technology.
  • SIMPLE, CLEAN-LABEL FORMULA: Just one non-medicinal ingredient (sodium stearyl fumarate) in a vegan hypromellose capsule - no gelatin and no unnecessary binders or fillers.
  • SIMPLE ONCE-DAILY DOSING: Take 3 capsules once daily with or without food, or as directed by a qualified health care practitioner.
  • VEGAN, NON-GMO, GLUTEN-FREE: Vegan hypromellose capsules, non-GMO and gluten-free, made in Canada.
  • TRUSTED CANADIAN QUALITY: Manufactured by Advanced Orthomolecular Research (AOR), a licensed Natural Health Product, NPN 80020741, since 1991.

Product description

Curcumin-95 - Standardized 95% Curcuminoid Turmeric Extract

AOR Curcumin 95

A closer look at AOR Curcumin-95 - a standardized curcuminoid extract from Curcuma longa (turmeric) rhizome, delivering 400 mg of curcumin at 95% curcuminoid potency per vegan capsule. Licensed Natural Health Product, NPN 80020741. Licensed Natural Health Product NPN 80020741.

Un regard plus approfondi sur AOR Curcumine-95 - un extrait normalisé de curcuminoïdes provenant du rhizome de Curcuma longa (curcuma), fournissant 400 mg de curcumine à une puissance de 95 % de curcuminoïdes par capsule végétalienne. Produit de santé naturel homologué, NPN 80020741.

Curcumin 95 lifestyle
AOR Curcumin 95
95% Curcuminoids · Vegan

Why A Standardized Curcuminoid Extract

A pure, potent 95% curcuminoid extract - the classic, well-studied form of curcumin, without added absorption-enhancement technology.

Concentrated, Standardized Potency

AOR Curcumin-95 is standardized to 95% curcuminoids, delivering a consistent, potent 400 mg dose of curcumin in every capsule - not a variable, low-potency turmeric powder.

The AOR Difference

A clean-label, single-ingredient formula - vegan, non-GMO, gluten-free and made in Canada, with just one non-medicinal ingredient.

Joint, Antioxidant & Wellness Support

Curcumin is the principal bioactive polyphenol in turmeric, studied for its antioxidant and anti-inflammatory properties for decades.

Joint Inflammation Relief

Used in herbal medicine to help relieve joint inflammation, supporting comfortable movement and mobility.

Antioxidant Defense

Provides antioxidants for the maintenance of good health, helping neutralize everyday oxidative stress.

Concentrated Curcuminoid Potency

Standardized to 95% curcuminoids for a consistent, potent 400 mg dose in every capsule.

Simple, Clean Formula

One non-medicinal ingredient in a vegan hypromellose capsule - no gelatin, fillers or unnecessary binders.

Foundational, Well-Studied Form

The classic standardized curcumin extract - the form behind decades of curcumin research - taken as a simple once-daily dose.

Overall Wellness

Curcumin's antioxidant and anti-inflammatory properties support the maintenance of good health as part of a daily routine.

AOR Curcumin 95: Supplement Facts

AOR™Curcumin 95
English

Medicinal Ingredients (per 1 capsule)

  • Curcumin from Curcuma longa (turmeric) rhizome, standardized to 95% curcuminoids400 mg

Non-Medicinal Ingredients: Sodium stearyl fumarate. Capsule: Hypromellose.

Recommended Use or Purpose: Provides antioxidants for the maintenance of good health. Used in herbal medicine to help relieve joint inflammation. Standardized to 95% curcuminoids from Curcuma longa (turmeric) rhizome extract. Licensed Natural Health Product, NPN 80020741.

Recommended Dose (Adults 18 years and over): Take 3 capsules daily with or without food, or as directed by a qualified health care practitioner. Do not mix, blend or crush capsules; swallow capsules whole. Do not exceed daily dose unless instructed by a healthcare practitioner.

Cautions and Warnings: Consult a health care practitioner before use if you are pregnant or breastfeeding, if you are taking antiplatelet medication or blood thinners, or if you have a liver or biliary disorder (including gallstones or a bile duct obstruction) or stomach ulcers or excess stomach acid. Consult a healthcare practitioner if symptoms persist or worsen. Stop use and consult a health care practitioner if you experience any new symptoms including yellowing of the eyes or skin, dark urine, nausea, vomiting, or stomach pain - possible signs of liver problems now flagged by Health Canada for oral turmeric/curcuminoid products (Health Canada Summary Safety Review, 2025). Do not use if the safety seal is broken. Store tightly sealed in a cool, dry place. Keep out of reach of children.

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.

Français

Ingrédients médicinaux (par 1 capsule)

  • Curcumine provenant du rhizome de Curcuma longa (curcuma), normalisée à 95 % de curcuminoïdes400 mg

Ingrédients non médicinaux : Stéarylfumarate de sodium. Capsule : Hypromellose.

Usage ou fins recommandés : Fournit des antioxydants pour le maintien d'une bonne santé. Utilisé en phytothérapie pour aider à soulager les inflammations articulaires. Normalisé à 95 % de curcuminoïdes provenant d'extrait de rhizome de Curcuma longa (curcuma). Produit de santé naturel homologué, NPN 80020741.

Dose recommandée (Adultes de 18 ans et plus) : Prendre 3 capsules par jour avec ou sans nourriture, ou selon les recommandations d'un professionnel de la santé qualifié. Ne pas mélanger, mélanger ou écraser les capsules. Avalez les capsules entières. Ne dépassez pas la dose quotidienne, sauf indication contraire d'un professionnel de la santé.

Mises en garde et précautions : Consultez un professionnel de la santé avant d'utiliser ce produit si vous êtes enceinte ou si vous allaitez, si vous prenez des médicaments antiplaquettaires ou des anticoagulants, ou si vous avez un trouble du foie ou biliaire (y compris des calculs biliaires ou une obstruction des voies biliaires) ou des ulcères d'estomac ou un excès d'acide gastrique. Consultez un professionnel de la santé si les symptômes persistent ou s'aggravent. Cessez d'utiliser et consultez un professionnel de la santé si vous développez de nouveaux symptômes, incluant le jaunissement des yeux ou de la peau, de l'urine foncée, des nausées, des vomissements ou des douleurs d'estomac - des signes possibles de problèmes hépatiques désormais signalés par Santé Canada pour les produits oraux à base de curcuma ou de curcuminoïdes (examen de synthèse de la sécurité de Santé Canada, 2025). Ne pas utiliser si le sceau de sécurité est brisé. Conserver hermétiquement fermé dans un endroit frais et sec. Garder hors de la portée des enfants.

NPN 80020741

Standardized 95% curcuminoids · 400 mg per capsuleVegan · Non-GMO · Gluten-free90 capsules · up to a 1-month supplyMade in Canada

Get concentrated 95% curcuminoid support for joints and antioxidant defense

Get AOR Curcumin-95 on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why AOR Curcumin-95

A pure, standardized 95% curcuminoid extract - the classic, well-studied form of curcumin.

Standardized 95% Curcuminoids

400 mg of curcumin per capsule from an extract standardized to 95% curcuminoids from Curcuma longa rhizome - consistent, potent, and quality-tested.

Joint & Antioxidant Support

Used in herbal medicine to help relieve joint inflammation, and provides antioxidants for the maintenance of good health.

Simple, Clean Formula

Just one non-medicinal ingredient (sodium stearyl fumarate) in a vegan hypromellose capsule.

Premium Canadian Brand

AOR - Advanced Orthomolecular Research, since 1991. Vegan, non-GMO, gluten-free. NPN 80020741.

How to use

Take 3 capsules, once daily

Adults (18 years and over) take 3 capsules daily with or without food, or as directed by a qualified health care practitioner.

Take with or without food

Flexible dosing fits any routine - a 90-capsule bottle is up to a 1-month supply at the full 3-capsule daily dose.

Swallow whole

Do not mix, blend or crush capsules - swallow capsules whole.

Stay consistent

Do not exceed the daily dose unless instructed by a healthcare practitioner; use consistently as part of your daily routine.

What the research says about curcumin and standardized turmeric extract

Peer-reviewed studies on curcumin, curcuminoids and turmeric extract generally - shared for education, not as claims about this finished product. Curcumin-95's claim is the statement authorized under its Natural Health Product licence, NPN 80020741. Some cards below discuss enhanced-absorption delivery technologies (e.g. piperine, liposomal, phospholipid-complexed) studied in the broader curcumin literature for educational comparison; Curcumin-95 itself is a standardized 95% curcuminoid extract without added absorption-enhancing technology.

Curcuminoid Research for Joint Support

Meta-analysis: turmeric and curcumin extracts eased arthritis symptoms across trials

Pooling randomized controlled trials identified through 12 databases, this systematic review and meta-analysis found that turmeric and curcumin extracts significantly reduced arthritis symptom scores compared with control, supporting their traditional use for joint discomfort.

Meta-analysis
Daily et al., Journal of Medicinal Food (2016)
Curcuminoid Research for Joint Support

Randomized trial: a curcumin extract performed comparably to a standard NSAID in knee osteoarthritis

In a 28-day randomized, open-label trial of 139 patients with knee osteoarthritis, a standardized curcumin extract (500 mg three times daily) produced reductions in pain and stiffness scores similar to the NSAID diclofenac, with a more favourable gastrointestinal safety profile.

Human RCT
Shep et al., Trials (2019)
Curcuminoid Research for Joint Support

Systematic review: curcumin supplementation showed benefit across rheumatoid arthritis trials

Analyzing six clinical trials totaling 539 rheumatoid arthritis patients, this systematic review and meta-analysis found curcumin supplementation was associated with improved disease-activity measures and a favourable safety profile relative to comparators.

Meta-analysis
Kou et al., Frontiers in Immunology (2023)
Antioxidant Mechanism Research

Foundational review: curcumin's dual antioxidant and anti-inflammatory action

This widely cited review describes how curcumin scavenges free radicals and interrupts the oxidative damage to lipids, DNA and proteins implicated in chronic conditions such as atherosclerosis and neurodegeneration, linking its antioxidant chemistry directly to its anti-inflammatory effects.

Review
Menon & Sudheer, Advances in Experimental Medicine and Biology (2007)
Antioxidant Mechanism Research

Mechanism review: curcumin helps protect cells from oxidative stress

This review examines how curcumin's antioxidant chemistry counters oxidative-stress-driven cell damage - including its interaction with lipid peroxidation and calcium homeostasis - illustrating the broader cytoprotective mechanisms behind curcumin's antioxidant reputation.

Review
Raman et al., Pharmacological Reports (2016)
Antioxidant Mechanism Research

Curcumin's antioxidant activity linked to healthy cellular aging

This review of curcumin's molecular mechanisms in aging describes how its antioxidant and anti-inflammatory properties help counter oxidative-stress pathways implicated in cellular senescence, one proposed basis for curcumin's traditional use in supporting healthy aging.

Review
Zia et al., Biomedicine & Pharmacotherapy (2020)
Bioavailability & Absorption Challenges

Landmark review: curcumin's poor natural bioavailability

This frequently cited review found that although oral curcumin is safe even at high doses (up to 12 g/day) in human trials, poor absorption, rapid metabolism and fast systemic elimination leave only low levels reaching the bloodstream and tissues - the central challenge behind curcumin research.

Review
Anand et al., Molecular Pharmaceutics (2007)
Bioavailability & Absorption Challenges

Review: why so little oral curcumin reaches circulation

Surveying over a hundred clinical studies, this review traces curcumin's bioavailability problem to poor intestinal absorption and extensive first-pass metabolism, and catalogs the delivery and formulation strategies researchers have explored to improve on a standard extract's absorption.

Review
Prasad et al., Cancer Research and Treatment (2014)
Bioavailability & Absorption Challenges

Bioavailability and health potential are directly linked

This review concludes that curcumin's broad spectrum of studied health properties is consistently limited by its poor pharmacokinetic profile - low small-intestinal absorption paired with extensive liver metabolism - framing absorption as a key variable in how much of curcumin's potential reaches the body.

Review
Dei Cas & Ghidoni, Nutrients (2019)
Safety & Tolerability Research

Scoping review of human curcumin trials found a generally consistent safety record

Reviewing 389 human clinical trial citations across eight databases, this scoping review found oral curcumin supplementation was generally well tolerated across a wide range of study populations and doses, while noting open questions about the extent of its biological activity given typical absorption.

Systematic Review
Panknin et al., International Journal of Molecular Sciences (2023)
Safety & Tolerability Research

Meta-analysis of 103 randomized trials on curcumin and human health

This large meta-analysis pooled 103 randomized controlled trials comparing Curcuma longa (turmeric/curcumin) with placebo across a range of health outcomes, contributing one of the broadest human evidence bases available for any single botanical supplement.

Meta-analysis
Jafari et al., Phytotherapy Research (2024)
Safety & Tolerability Research

Case reports flag rare liver injury from high-dose turmeric/curcumin supplements

A systematic review of Italian phytovigilance data and published case reports found rare instances of acute, generally reversible liver injury associated with Curcuma longa (turmeric/curcumin) supplements, most often at high doses. Health Canada has since acted on this signal, updating its turmeric and curcuminoid monographs in 2025 to require a liver-symptom stop-use warning on all licensed products in this category, including this one - reflected in this product's safety information above.

Systematic Review
Lombardi et al., British Journal of Clinical Pharmacology (2020)
Comparative Curcumin-Form Research

The landmark study behind absorption-enhanced curcumin formulations

This classic trial found that co-administering piperine (a black pepper extract) with curcumin increased human serum curcumin concentrations by 2000%, establishing the scientific basis that later inspired the absorption-enhancement technologies used in some enhanced curcumin products on the market today. Curcumin-95 does not contain piperine or any added absorption enhancer.

Human study
Shoba et al., Planta Medica (1998)
Comparative Curcumin-Form Research

Phase I trial: an enhanced-delivery curcumin form's absorption profile

In this randomized, placebo-controlled Phase I trial, a liposomal curcumin preparation given intravenously showed dose-dependent increases in plasma concentration, illustrating how specialized delivery technologies are studied specifically to raise the blood levels that a standard oral curcumin extract does not reach on its own.

Human RCT
Storka et al., International Journal of Clinical Pharmacology and Therapeutics (2015)
Comparative Curcumin-Form Research

Review: the range of strategies developed to improve curcumin's absorption

This review catalogs the major approaches researchers have developed to counter curcumin's poor natural absorption - including nanoparticle, phospholipid and piperine-based delivery systems - useful context for how enhanced-absorption curcumin products differ technologically from a standard standardized extract like Curcumin-95.

Review
Tabanelli et al., Pharmaceutics (2021)
Foundational Turmeric & Curcuminoid Biochemistry

Curcumin: the active compound behind turmeric's traditional use

This review traces curcumin's identity as the principal bioactive polyphenol in turmeric (Curcuma longa), a spice used for centuries across Asian traditional medicine, and surveys the chemistry underlying its characteristic orange-yellow color and broad range of studied health effects.

Review
Kocaadam & Şanlier, Critical Reviews in Food Science and Nutrition (2017)
Foundational Turmeric & Curcuminoid Biochemistry

Curcumin's two-century history as turmeric's defining compound

This widely cited chapter traces curcumin's isolation nearly two centuries ago and its structural identification as diferuloylmethane in 1910, documenting how a compound used since antiquity in traditional preparations became one of the most-studied natural compounds in modern biochemistry.

Review
Aggarwal et al., Advances in Experimental Medicine and Biology (2007)
Foundational Turmeric & Curcuminoid Biochemistry

Mapping curcumin's molecular targets in the body

This review surveys the diverse molecular targets curcumin engages - including transcription factors and enzymes tied to its antioxidant and anti-inflammatory activity - reflecting the breadth of biochemical research into how this single polyphenol produces such wide-ranging effects.

Review
Zhou et al., Current Drug Targets (2011)
Dosing & Absorption Research

Foundational review: curcumin's dose-response and metabolism

This review of preclinical and Phase I human data found that curcumin is efficiently metabolized on first pass through the liver and intestine, primarily via glucuronidation and sulfation, establishing the metabolic basis researchers use to interpret curcumin dosing studies.

Review
Sharma et al., Advances in Experimental Medicine and Biology (2007)
Dosing & Absorption Research

Human trial: high-dose oral curcumin's absorption and biological activity

In this Phase I pilot study, ten healthy men received 12 g of oral curcumin; researchers measured its pharmacokinetics and found it induced heme oxygenase-1, an antioxidant-linked enzyme - direct human evidence that oral curcumin exerts measurable biological activity despite its known absorption limits.

Human study
Klickovic et al., BioMed Research International (2014)
Dosing & Absorption Research

Pharmacokinetic modeling of a commercially marketed curcumin supplement

This clinical study modeled the acute pharmacokinetics and pharmacodynamics of a commercially marketed curcumin supplement in healthy volunteers, linking measured blood levels to antioxidant and epigenetic gene-expression changes and offering a real-world dosing reference point.

Human study
Cheng et al., Molecular Pharmaceutics (2019)
Anti-Inflammatory Pathway Research

Mechanism study: curcumin calms an inflammatory signaling pathway in joint cells

In laboratory models of gout-like crystal-induced inflammation, curcumin blocked the breakdown of a key inhibitory protein (IκBα) and reduced mitochondrial damage, interrupting the NF-κB signaling cascade that drives inflammatory cytokine release in joint tissue.

Mechanism
Chen et al., Arthritis Research & Therapy (2019)
Anti-Inflammatory Pathway Research

Review: curcumin as a modulator of the inflammasome

This review outlines how curcumin's anti-inflammatory and antioxidant effects converge on the inflammasome, a cellular complex that activates NF-κB-linked inflammatory cytokines including IL-1β and IL-18, positioning curcumin as a broad modulator of this key inflammatory pathway.

Review
Hasanzadeh et al., Pharmacological Research (2020)
Anti-Inflammatory Pathway Research

Curcumin shifts inflammatory signaling toward a protective pathway

In laboratory models of inflammation-activated immune cells, curcumin promoted a shift from an inflammatory to a protective activation state via the TREM2/TLR4/NF-κB signaling axis, illustrating a specific molecular route behind its anti-inflammatory reputation.

Mechanism
Zhang et al., Molecular Immunology (2019)

Frequently asked questions

What is AOR Curcumin-95?

A standardized curcuminoid extract from Curcuma longa (turmeric) rhizome - 400 mg of curcumin per capsule, standardized to 95% curcuminoids. It is a licensed Natural Health Product, NPN 80020741.

How do I take it?

Adults (18 years and over) take 3 capsules daily with or without food, or as directed by a qualified health care practitioner. Do not mix, blend or crush capsules - swallow whole.

Is this the same as AOR's other curcumin products?

No. Curcumin-95 is a standardized 95% curcuminoid extract - the classic, well-studied form of curcumin, without added absorption-enhancement technology. Some other curcumin products use patented absorption-enhancement technologies; Curcumin-95 is the pure, standardized extract.

Why does curcumin absorption matter?

Curcumin is naturally poorly absorbed - research shows it is rapidly metabolized and eliminated, so only a small fraction reaches the bloodstream. This is a well-documented characteristic of standardized curcumin extracts generally, not specific to any one product.

How much curcumin does each capsule provide, and how long does a bottle last?

Each capsule provides 400 mg of curcumin from an extract standardized to 95% curcuminoids. At the full labelled dose of 3 capsules daily, that is 1200 mg of curcumin per day, and a 90-capsule bottle is up to a 1-month supply.

Is it vegan and allergen-friendly?

Yes - vegan hypromellose capsules, non-GMO and gluten-free, with only one non-medicinal ingredient (sodium stearyl fumarate).

Who should not use it?

Consult a health care practitioner before use if you are pregnant, taking antiplatelet medication or blood thinners, or if you have a liver or biliary disorder (including gallstones or a bile duct obstruction) or stomach ulcers or excess stomach acid. Consult a health care practitioner if symptoms persist or worsen.

What if I notice stomach pain, nausea, or yellowing of the skin or eyes while taking it?

Stop use and consult a health care practitioner right away. Health Canada updated its turmeric and curcuminoid product monographs in 2025 to flag these as possible signs of rare, usually reversible liver problems reported with oral turmeric/curcumin supplements - this is reflected in this product's safety information above.

Standardized 95% curcuminoids · 400 mg per capsuleVegan · Non-GMO · Gluten-free90 capsules · up to a 1-month supplyMade in Canada

Get concentrated 95% curcuminoid support for joints and antioxidant defense

Get AOR Curcumin-95 on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80020741. Curcumin-95 provides a standardized curcuminoid extract from Curcuma longa (turmeric) rhizome (400 mg curcumin, standardized to 95% curcuminoids, per capsule). The research summaries below concern curcumin, curcuminoids and turmeric extract generally and are educational - they are not claims about this finished product. Read and follow the label. Consult a health care practitioner before use if you are pregnant, taking antiplatelet medication or blood thinners, have gallstones or a bile duct obstruction, or have stomach ulcers or excess stomach acid. Results may vary.

Important information

Safety Information

Cautions and Warnings: Consult a health care practitioner before use if you are pregnant or breastfeeding, if you are taking antiplatelet medication or blood thinners, or if you have a liver or biliary disorder (including gallstones or a bile duct obstruction) or stomach ulcers or excess stomach acid. Consult a healthcare practitioner if symptoms persist or worsen. Stop use and consult a health care practitioner if you experience any new symptoms including yellowing of the eyes or skin, dark urine, nausea, vomiting, or stomach pain - possible signs of liver problems now flagged by Health Canada for oral turmeric/curcuminoid products (Health Canada Summary Safety Review, 2025). Do not use if the safety seal is broken. Store tightly sealed in a cool, dry place. Keep out of reach of children.

Indications

Recommended Use or Purpose: Provides antioxidants for the maintenance of good health. Used in herbal medicine to help relieve joint inflammation. Standardized to 95% curcuminoids from Curcuma longa (turmeric) rhizome extract. Licensed Natural Health Product, NPN 80020741.

Ingredients

Medicinal Ingredients (per 1 capsule): Curcumin (Curcuma longa, 95% curcuminoids) 400 mg. Non-medicinal Ingredients: Sodium stearyl fumarate. Capsule: Hypromellose. NMIs are subject to change - always read and follow the label.

Directions

Recommended Dose (Adults 18 years and over): Take 3 capsules daily with or without food, or as directed by a qualified health care practitioner. Do not mix, blend or crush capsules; swallow capsules whole. Do not exceed daily dose unless instructed by a healthcare practitioner.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than shown on our website. Always read labels, warnings and directions before using or consuming a product. This item is sold and shipped by Amazon.ca; purchases are completed on Amazon.