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Health Canada NPN 80061724 500 mg High-Potency L-Carnosine Vegan · Non-GMO · Gluten-Free 60 Capsules - up to a 2-Month Supply
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AOR L-Carnosine 500mg - Antioxidant & Muscle Support | 60-120 Caps

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$45.63 CAD
Get it on Amazon.ca
BrandAOR
Serving500 mg (1 capsule)
Licensed Natural Health ProductNPN 80061724
Quality StandardsGMP-compliant facility
CountryMade in Canada Made in Canada

About this item

  • SUPPORTS MUSCLE BUILDING, REPAIR & RECOVERY: Provides a source of amino acids involved in muscle protein synthesis - supporting muscle building, repair and recovery after physical activity.
  • ANTIOXIDANT SUPPORT FOR CELLULAR PROTECTION: A source of antioxidants that help protect cells against the oxidative damage caused by free radicals.
  • SUPPORTS COGNITIVE FUNCTION & MENTAL CLARITY: Contributes to muscle and neurological wellness, supporting cognitive function and everyday mental clarity.
  • SUPPORTS CELLULAR RENEWAL & VITALITY: Broad-spectrum antioxidant support for cellular longevity, as part of a healthy-aging routine.
  • VEGAN-FRIENDLY AMINO ACID SOURCE: Suitable for vegetarians and vegans as a source of an amino acid derivative that may be limited in plant-based diets, where dietary intake comes mainly from meat.
  • HIGH-POTENCY, SINGLE-INGREDIENT FORMULA: 500 mg of pure L-carnosine per vegi-capsule, with no non-medicinal ingredients besides the hypromellose capsule shell.
  • VEGAN, NON-GMO & GLUTEN-FREE: A clean, single-ingredient formula - vegan, non-GMO and gluten-free vegi-capsules.
  • PREMIUM CANADIAN QUALITY: Made in Canada in a GMP-compliant facility by Advanced Orthomolecular Research (AOR), licensed under Health Canada NPN 80061724.

Product Description

L-Carnosine - A High-Potency Antioxidant Amino Acid Dipeptide

AOR Carnosine

A high-potency 500 mg dose of L-carnosine, the naturally occurring antioxidant dipeptide found in muscle and brain tissue. AOR Carnosine-500 provides a source of amino acids involved in muscle protein synthesis and a source of antioxidants that help protect cells against oxidative damage - in a vegan, single-ingredient vegi-capsule. Licensed Natural Health Product NPN 80061724.

Une dose de 500 mg de L-carnosine, le dipeptide antioxydant que l'on trouve naturellement dans les muscles et le cerveau. AOR Carnosine-500 est une source d'acides aminés impliqués dans la synthèse des protéines musculaires et une source d'antioxydants qui aident à protéger les cellules contre les dommages oxydatifs - en végécapsule végane à ingrédient unique. Produit de santé naturel homologué. NPN 80061724.

Carnosine lifestyle
AOR Carnosine
Premium - AOR

High-Potency Carnosine, 500 mg

Single-ingredient, vegan vegi-capsules - Non-GMO, Gluten-Free

High-Potency 500 mg Dose

One capsule delivers 500 mg of L-carnosine daily - a stand-alone, high-potency dose of this naturally occurring antioxidant dipeptide.

The AOR Difference

Pure L-carnosine with no non-medicinal ingredients - vegan, non-GMO and gluten-free, made in Canada to GMP quality standards.

What AOR Carnosine-500 Supports

Four ways this antioxidant amino acid dipeptide supports the body.

Antioxidant Protection

Supports defense against oxidative damage, helping protect cells from free-radical stress.

Cellular Longevity

Helps protect cells from age-related oxidative decline, supporting cellular health over time.

Muscle & Nerve Health

A source of amino acids involved in muscle protein synthesis, contributing to muscle and neurological wellness.

Healthy Aging

Provides broad-spectrum antioxidant support as part of a healthy-aging routine.

AOR Carnosine: Supplement Facts

AOR™Carnosine
English

Each Vegi-Capsule contains:

  • L-Carnosine500 mg

Non-Medicinal Ingredients: None. Capsule: hypromellose.

Recommended Use or Purpose: A source of amino acids involved in muscle protein synthesis. A source of antioxidants.

Recommended Dose (Adults 18 years and older): Take 1 capsule daily without food, or as directed by a qualified health care practitioner. Do not crush, mix or blend capsules; swallow the capsule whole. Do not exceed the recommended daily dose unless directed by a health care practitioner. Recommended Duration of Use: Consult a health care practitioner for use beyond 8 weeks.

Cautions and Warnings: Consult a health care practitioner before use if you are pregnant or breastfeeding. Consult a health care practitioner for use beyond 8 weeks. Do not use if the safety seal is broken. Store tightly sealed in a cool, dry place, away from children.

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings and directions before using or consuming a product. Other Information: GMP manufacturing, independent testing, quality assured. Manufactured by Advanced Orthomolecular Research (AOR), Calgary, Alberta. This item is sold and shipped by Amazon.ca.

Français

Chaque végécapsule contient :

  • L-Carnosine500 mg

Ingrédients non médicinaux : Aucun. Capsule : hypromellose.

Usage ou fins recommandés : Une source d'acides aminés impliqués dans la synthèse des protéines musculaires. Une source d'antioxydants.

Dose recommandée (adultes de 18 ans et plus) : Prendre 1 capsule par jour sans manger, ou selon les recommandations d'un praticien de la santé qualifié. Ne pas écraser, mélanger ou mixer les capsules; avaler la capsule entière. Ne pas dépasser la dose quotidienne recommandée sauf indication contraire d'un praticien de la santé. Durée d'utilisation recommandée : consulter un praticien de la santé pour un usage au-delà de 8 semaines.

Mises en garde : Consulter un praticien de soins de santé avant l'utilisation si vous êtes enceinte ou si vous allaitez. Consulter un praticien de soins de santé pour un usage au-delà de 8 semaines. Ne pas utiliser si le sceau de sécurité est brisé. Conserver hermétiquement fermé dans un endroit frais et sec, hors de la portée des enfants.

NPN 80061724

500 mg high-potency L-carnosine60 vegi-capsules · up to 2-month supplyVegan · Non-GMO · Gluten-freeMade in Canada

Add AOR Carnosine-500 to your daily routine

Get AOR Carnosine-500 on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Why AOR Carnosine-500

A high-potency, single-ingredient antioxidant amino acid dipeptide - premium AOR quality.

High-potency single ingredient

500 mg of pure L-carnosine per capsule, with no non-medicinal ingredients besides the capsule shell.

Antioxidant & cellular support

A source of antioxidants that help protect cells against oxidative damage, supporting cellular longevity.

Muscle & cognitive wellness

A source of amino acids involved in muscle protein synthesis, supporting muscle, nerve and cognitive function.

Premium Canadian brand

AOR - Advanced Orthomolecular Research, since 1991. NPN 80061724.

How to use it

Take 1 capsule daily

Adults take 1 vegi-capsule daily without food, or as directed by a qualified health care practitioner.

Swallow whole

Do not crush, mix or blend capsules - swallow the capsule whole with water.

Guided long-term use

Consult a health care practitioner for use beyond 8 weeks.

What the research says about L-carnosine

Educational summaries of published research on the amino acid dipeptide L-carnosine (and closely related beta-alanine/histidine research); not product-specific claims. AOR Carnosine-500's claim is the traditional/authorized antioxidant use under NPN 80061724.

Antioxidant & Anti-Glycation Mechanism

Direct and indirect antioxidant pathways

A mechanistic review describes how carnosine directly scavenges reactive carbonyl species and also indirectly activates the Nrf2 antioxidant pathway, helping explain its broad antioxidant and anti-glycation effects.

Mechanism review
Aldini et al., Free Radical Research (2020)
Antioxidant & Anti-Glycation Mechanism

A versatile antioxidant and antiglycating agent

An early review described carnosine as a naturally occurring antioxidant and metal-chelating agent that also inhibits formation of advanced glycation end-products, attenuating cellular oxidative stress.

Review
Reddy et al., Science of Aging Knowledge Environment (2005)
Antioxidant & Anti-Glycation Mechanism

Systematic review of anti-glycation evidence

A systematic review of 36 in vitro, animal and human studies found carnosine consistently helped prevent formation of advanced glycation end-products, supporting its anti-glycating properties.

Systematic review
Ghodsi & Kheirouri, Amino Acids (2018)
Muscle Carnosine & Exercise Performance

Meta-analysis of beta-alanine and exercise capacity

A systematic review and meta-analysis of 40 studies found that beta-alanine supplementation, which raises muscle carnosine, produced a significant overall improvement in exercise capacity and performance.

Meta-analysis
Saunders et al., British Journal of Sports Medicine (2017)
Muscle Carnosine & Exercise Performance

Benefits for maximal-intensity training

A meta-analysis of 18 studies in trained young men found beta-alanine supplementation improved maximal-intensity exercise performance, with the largest effects after at least 4 weeks of use.

Meta-analysis
Georgiou et al., International Journal of Sport Nutrition and Exercise Metabolism (2024)
Muscle Carnosine & Exercise Performance

How muscle carnosine supports performance

A review explains that beta-alanine raises muscle carnosine, increasing the muscle's buffering capacity and improving performance during repeated high-intensity exercise bouts.

Review
Artioli et al., Medicine & Science in Sports & Exercise (2010)
Cognitive Aging & Neuroprotection

Improved cognitive function in aging models

In aged rats, carnosine treatment improved performance on a maze-based cognitive test and reduced markers of aging-related brain protein changes compared to untreated aged animals.

Animal study
Banerjee et al., Journal of Neurochemistry (2021)
Cognitive Aging & Neuroprotection

Meta-analysis on cognitive decline

A systematic review and meta-analysis of human trials found that 12 weeks of carnosine/anserine supplementation (1 g/day) improved global cognitive function scores in elderly subjects.

Meta-analysis
Caruso et al., Biomedicines (2021)
Cognitive Aging & Neuroprotection

Preclinical promise for neurodegeneration

A 2025 review of preclinical research describes carnosine's antioxidant, anti-inflammatory and anti-glycation actions as supporting its investigation for age-related neurodegenerative conditions.

Review
Barbati et al., AIMS Neuroscience (2025)
Cellular pH-Buffering

An intracellular pH buffer in muscle

The International Society of Sports Nutrition's position stand describes carnosine as acting as an intracellular pH buffer in skeletal muscle, helping offset the acidity produced during intense exercise.

Position stand
Trexler et al., Journal of the International Society of Sports Nutrition (2015)
Cellular pH-Buffering

Buffering and calcium regulation

A review of carnosine's biochemical properties highlights its role as an intramuscular pH buffer and calcium regulator, alongside its antiglycation and antioxidant activity.

Review
Blancquaert et al., Current Opinion in Clinical Nutrition and Metabolic Care (2015)
Cellular pH-Buffering

A buffer built from two amino acids

A review of histidine metabolism notes that carnosine, formed from histidine and beta-alanine in muscle and brain tissue, functions as an important cellular buffer and antioxidant.

Review
Brosnan & Brosnan, The Journal of Nutrition (2020)
Safety & Tolerability

Human dose-escalation safety study

A dose-escalation study in healthy adult volunteers found oral carnosine was safe and well tolerated at doses up to 10 g, with long-term twice-daily dosing at 5 g producing no adverse events.

Human study
Ali et al., Nutrients (2025)
Safety & Tolerability

No toxicity in a safety evaluation

In a preclinical safety and efficacy evaluation, carnosine treatment showed no evidence of adverse effects or toxicity across blood counts, organ histology and serum chemistry.

Animal study
Bae et al., Stroke (2013)
Safety & Tolerability

Reviewing the safety evidence

A systematic review of beta-alanine research noted generally favourable tolerability, while highlighting the value of continued monitoring of supplementation safety in athletic populations.

Systematic review
Quesnele et al., International Journal of Sport Nutrition and Exercise Metabolism (2013)
Histidine-Containing Dipeptides Compared

Comparing carnosine, anserine and beta-alanine

A meta-analysis of randomized trials found histidine-containing dipeptide supplementation - including carnosine, anserine and beta-alanine - was associated with reduced depression scores and improved quality-of-life measures.

Meta-analysis
Kabthymer et al., Nutrition Reviews (2025)
Histidine-Containing Dipeptides Compared

Carnosine's chemical relatives

A narrative review compares carnosine to related histidine-containing compounds - anserine, balenine and ergothioneine - each showing antioxidant and exercise-related properties in animal and human research.

Review
Jędrejko et al., Nutrients (2025)
Histidine-Containing Dipeptides Compared

A century of comparative research

An early comparative review of carnosine and anserine describes their shared distribution in skeletal muscle and their antioxidant, membrane-protective properties across species.

Review
Boldyrev & Severin, Advances in Enzyme Regulation (1990)
Foundational Biochemistry

A century of carnosine research

A comprehensive physiology review traces carnosine's discovery in 1900 and details its pH-buffering, metal-chelating and antioxidant biochemistry across muscle and brain tissue.

Comprehensive review
Boldyrev, Aldini & Derave, Physiological Reviews (2013)
Foundational Biochemistry

Rethinking an old molecule

A review traces the evolving scientific understanding of carnosine, from an early view as a simple metabolic byproduct to its modern recognition as an intracellular signaling regulator.

Review
Boldyrev, Biochemistry (Moscow) (2012)
Foundational Biochemistry

Mapping carnosine's therapeutic mechanisms

A 2025 review summarizes carnosine's antioxidant and anti-glycation biochemistry and its mechanisms of interest across neurodegenerative, metabolic and cardiovascular research.

Review
Fang et al., International Journal of Molecular Medicine (2025)
Aging & Longevity

Extending lifespan in a classic model organism

Carnosine supplementation extended the average lifespan of male fruit flies in a dose-dependent manner, an effect attributed to protection against age-related free-radical accumulation.

Animal study
Yuneva et al., Bulletin of Experimental Biology and Medicine (2002)
Aging & Longevity

A dietary antioxidant among longevity pathways

A review of cellular stress-response pathways linked to aging and longevity names carnosine among dietary antioxidants capable of activating protective 'vitagene' pathways.

Review
Calabrese et al., Molecular Aspects of Medicine (2011)
Aging & Longevity

Nutritional support for healthy brain aging

A review of cellular stress responses in aging and neurodegeneration highlights carnosine, alongside other dietary antioxidants, as activating protective pathways of interest for healthy aging.

Review
Calabrese et al., Neurochemical Research (2008)

Frequently asked questions

What is L-carnosine and what does it do?

L-carnosine is a naturally occurring amino acid dipeptide found in muscle and brain tissue. AOR Carnosine-500 provides a source of amino acids involved in muscle protein synthesis and a source of antioxidants.

How do I take AOR Carnosine-500?

Adults take 1 capsule daily without food, or as directed by a qualified health care practitioner. Swallow the capsule whole - do not crush, mix or blend. Consult a health care practitioner for use beyond 8 weeks.

What's the difference between the 60- and 120-capsule sizes?

Both contain the exact same 500 mg L-carnosine formula under the same NPN license - the 60-capsule bottle is a 60-day supply and the 120-capsule bottle is a 120-day supply, at one capsule per day.

Is it vegan and allergen-friendly?

Yes - vegan, non-GMO and gluten-free, with no non-medicinal ingredients besides the hypromellose vegi-capsule shell.

Can vegetarians and vegans use it?

Yes - it's a vegan formula, making it a suitable source of this amino acid derivative for those on plant-based diets, where dietary carnosine (found mainly in meat) may otherwise be limited.

Who should not use it?

Consult a health care practitioner before use if you are pregnant or breastfeeding, or for use beyond 8 weeks.

Is it made in Canada?

Yes - manufactured by Advanced Orthomolecular Research (AOR) in Calgary, Alberta, in a GMP-compliant facility, and licensed by Health Canada under NPN 80061724.

Where do I buy it?

Use the orange button on this page - it takes you to the AOR listing on Amazon.ca for secure checkout and fast delivery.

500 mg high-potency L-carnosine60 vegi-capsules · up to 2-month supplyVegan · Non-GMO · Gluten-freeMade in Canada

Add AOR Carnosine-500 to your daily routine

Get AOR Carnosine-500 on Amazon.ca - fast, protected delivery.

Get it on Amazon.ca

Natural Health Product NPN 80061724. L-Carnosine is a naturally occurring amino acid dipeptide and a source of antioxidants. The research summaries below concern the ingredient L-carnosine (and related beta-alanine/histidine research) generally and are educational - they are not product-specific claims. Read and follow the label. Consult a health care practitioner before use if you are pregnant or breastfeeding, or for use beyond 8 weeks. Results may vary.

Important information

Safety Information

Cautions and Warnings: Consult a health care practitioner before use if you are pregnant or breastfeeding. Consult a health care practitioner for use beyond 8 weeks. Do not use if the safety seal is broken. Store tightly sealed in a cool, dry place, away from children.

Indications

Recommended Use or Purpose: A source of amino acids involved in muscle protein synthesis. A source of antioxidants.

Ingredients

Medicinal Ingredients: Serving Size: 1 Capsule. L-Carnosine 500 mg. Daily Value not established. Non-medical Ingredients: none. Capsule: hypromellose.

Directions

Recommended Dose (Adults 18 years and older): Take 1 capsule daily without food, or as directed by a qualified health care practitioner. Do not crush, mix or blend capsules; swallow the capsule whole. Do not exceed the recommended daily dose unless directed by a health care practitioner. Recommended Duration of Use: Consult a health care practitioner for use beyond 8 weeks.

Legal Disclaimer

Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings and directions before using or consuming a product. Other Information: GMP manufacturing, independent testing, quality assured. Manufactured by Advanced Orthomolecular Research (AOR), Calgary, Alberta. This item is sold and shipped by Amazon.ca.